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PAPPA2 [extracellular region]
Stable Identifier
R-HSA-3009046
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
Pappalysin-2 ecNumber3.4.24.-/ecNumber, PAPP2_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) (Homo sapiens)
PAAP-A proteolyzes IGF:IGFBP4 (Homo sapiens)
PAPPA,PAPPA2 [extracellular region] (Homo sapiens)
PAPPA2 [extracellular region] (Homo sapiens)
PAPP-A2 proteolyzes IGF:IGFBP5:ALS (Homo sapiens)
PAPPA,PAPPA2 [extracellular region] (Homo sapiens)
PAPPA2 [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9BXP8 PAPPA2
Gene Names
PAPPA2, PLAC3
Chain
signal peptide:1-22, propeptide:23-234, chain:235-1791
Reference Genes
BioGPS Gene:60676 PAPPA2
COSMIC (genes):PAPPA2 PAPPA2
CTD Gene:60676 PAPPA2
dbSNP Gene:60676 PAPPA2
ENSEMBL:ENSG00000116183 PAPPA2
HGNC:14615 PAPPA2
KEGG:hsa:60676 PAPPA2
Monarch:60676 PAPPA2
NCBI Gene:60676 PAPPA2
OMIM:619485 PAPPA2
UCSC:Q9BXP8 PAPPA2
Reference Transcript
RefSeq:XM_054338083.1 PAPPA2
RefSeq:XM_054338080.1 PAPPA2
RefSeq:XM_054338079.1 PAPPA2
RefSeq:XM_054338085.1 PAPPA2
RefSeq:NM_021936.3 PAPPA2
RefSeq:XM_054338081.1 PAPPA2
RefSeq:XM_047427180.1 PAPPA2
RefSeq:XM_017002025.1 PAPPA2
RefSeq:XM_005245422.4 PAPPA2
RefSeq:XM_054338084.1 PAPPA2
RefSeq:XM_011509858.2 PAPPA2
RefSeq:XM_011509857.1 PAPPA2
RefSeq:XM_017002023.2 PAPPA2
RefSeq:XM_017002024.2 PAPPA2
RefSeq:XM_054338082.1 PAPPA2
RefSeq:NM_020318.3 PAPPA2
Other Identifiers
11737625_a_at
11737867_a_at
11737868_x_at
11751971_a_at
11762391_x_at
16674151
211918_PM_x_at
211918_x_at
213332_PM_at
213332_at
228237_PM_at
228237_at
2368591
2368593
2368594
2368595
2368596
2368597
2368598
2368603
2368608
2368609
2368610
2368611
2368612
2368613
2368614
2368615
2368616
2368617
2368619
2368620
2368621
2368622
2368623
2368629
2368630
2368631
2368635
2368641
2368644
2368645
2368646
2368655
2368656
2368657
2368660
2368670
2368671
2368672
2368673
2368674
2368675
2368676
2368677
39151_at
58487_at
60676
7907572
A_14_P104369
A_14_P114420
A_23_P23873
A_33_P3376838
GE476242
GE56082
GO:0001558
GO:0003824
GO:0004222
GO:0005515
GO:0005576
GO:0005615
GO:0006508
GO:0007166
GO:0008237
GO:0008270
GO:0009651
GO:0016324
GO:0016787
GO:0043226
GO:0046872
GO:0060349
GO:0070062
GO:0140096
HMNXSV003005369
HMNXSV003041762
Hs.106095.0.A1_3p_at
Hs.9654.0.S1_3p_at
ILMN_1708529
ILMN_1792002
PH_hs_0015273
TC01001534.hg
TC01004845.hg
TC01004846.hg
g13569344_3p_s_at
p25708
Participates
as a member of
PAPPA,PAPPA2 [extracellular region] (Homo sapiens)
Inferred To
pappa2 [extracellular region]
(Xenopus tropicalis)
PAPPA2 [extracellular region]
(Bos taurus)
PAPPA2 [extracellular region]
(Canis familiaris)
PAPPA2 [extracellular region]
(Gallus gallus)
PAPPA2 [extracellular region]
(Sus scrofa)
Pappa2 [extracellular region]
(Mus musculus)
Pappa2 [extracellular region]
(Rattus norvegicus)
Cross References
RefSeq
XP_016857514.1
,
XP_054194058.1
,
XP_054194056.1
,
XP_054194059.1
,
XP_054194057.1
,
XP_016857513.1
,
XP_016857512.1
,
NP_064714.2
,
XP_011508160.1
,
XP_011508159.1
,
XP_054194060.1
,
XP_054194054.1
,
XP_054194055.1
,
XP_005245479.1
,
NP_068755.2
,
XP_047283136.1
OpenTargets
ENSG00000116183
ENSEMBL
ENSP00000356634
,
ENSP00000356633
,
ENST00000367661
,
ENST00000367662
,
ENSG00000116183
HPA
ENSG00000116183-PAPPA2
GeneCards
PAPPA2
PRO
Q9BXP8
Pharos - Targets
Q9BXP8
GlyGen
Q9BXP8
PDB
8SL1
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