Reactome | AOC1 [plasma membrane]

AOC1 [plasma membrane]

Stable Identifier

R-HSA-2889048

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Amiloride-sensitive amine oxidase [copper-containing], ABP1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P19801 AOC1

Gene Names

AOC1, ABP1, DAO1, DAO

Chain

signal peptide:1-19, chain:20-751

Reference Genes

BioGPS Gene:26 AOC1

COSMIC (genes):AOC1 AOC1

COSMIC (genes):DAO AOC1

CTD Gene:26 AOC1

dbSNP Gene:26 AOC1

ENSEMBL:ENSG00000002726 AOC1

HGNC:80 AOC1

KEGG:hsa:26 AOC1

Monarch:26 AOC1

NCBI Gene:26 AOC1

OMIM:104610 AOC1

UCSC:P19801 AOC1

Reference Transcript

Other Identifiers

11719962_s_at

17053436

203559_PM_s_at

203559_s_at

3031651

3031653

3031661

3031662

3031663

3031666

3031667

3031668

3031669

3031671

3031672

3031675

3031676

3031677

37186_s_at

74904_at

8137271

A_14_P114354

A_23_P59452

GE58928

GO:0003824

GO:0005507

GO:0005509

GO:0005515

GO:0005576

GO:0005615

GO:0005777

GO:0005886

GO:0005923

GO:0008131

GO:0008201

GO:0009308

GO:0009445

GO:0016491

GO:0016641

GO:0035580

GO:0042803

GO:0043226

GO:0046677

GO:0046872

GO:0048038

GO:0050232

GO:0052597

GO:0052598

GO:0070062

HMNXSV003019334

ILMN_1731433

PH_hs_0025599

RNA95517|RNS_599_149

TC07001008.hg

U11862_s_at

g4501850_3p_a_at

Participates

as a component of

AOC1 dimer:2xCu2+:4xCa2+ [plasma membrane] (Homo sapiens)

Other forms of this molecule

AOC1 [specific granule lumen]

AOC1 [extracellular region]

Inferred To

aoc1 [plasma membrane] (Danio rerio)

aoc1 [plasma membrane] (Xenopus tropicalis)

AOC1 [plasma membrane] (Bos taurus)

AOC1 [plasma membrane] (Gallus gallus)

AOC1 [plasma membrane] (Mus musculus)

AOC1 [plasma membrane] (Rattus norvegicus)

AOC1 [plasma membrane] (Sus scrofa)

Cross References

OpenTargets

ENSG00000002726

ENSEMBL

ENSP00000411613, ENST00000360937, ENSP00000354193, ENST00000416793, ENST00000467291, ENST00000493429, ENSP00000418328, ENSP00000418614, ENSG00000002726

ZINC - FDA approved

AOC1_HUMAN

ZINC - Substances

AOC1_HUMAN

ZINC target

P19801

ZINC - Biogenic

AOC1_HUMAN

PRO

P19801

GlyGen

P19801

PDB

3K5T, 3HII, 3HIG, 3HI7, 3MPH

ZINC - Investigational

AOC1_HUMAN

HPA

ENSG00000002726-AOC1

GeneCards

AOC1

Pharos - Targets

P19801

ZINC - Predictions - Purchasable

AOC1_HUMAN

HMDB Protein

HMDBP00390

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O75593 FOXH1	1	FOXH1 [nucleoplasm] (R-HSA-1225914)	0.556	3

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