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SCN4B [plasma membrane]
Stable Identifier
R-HSA-2671926
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Sodium channel subunit beta-4, SCN4B_HUMAN
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Nervous system development (Homo sapiens)
Axon guidance (Homo sapiens)
L1CAM interactions (Homo sapiens)
Interaction between L1 and Ankyrins (Homo sapiens)
Ankyrins link voltage-gated sodium and potassium channels to spectrin and L1 (Homo sapiens)
KCNQ2,3, SCNAs:SCNBs [plasma membrane] (Homo sapiens)
SCNAs:SCNBs [plasma membrane] (Homo sapiens)
SCNBs [plasma membrane] (Homo sapiens)
SCN4B [plasma membrane] (Homo sapiens)
NFASC:NRCAM:ANK1-3:SPTA:SPTB:F-actin:KCNQ2,3, SCNAs:SCNBs [plasma membrane] (Homo sapiens)
KCNQ2,3, SCNAs:SCNBs [plasma membrane] (Homo sapiens)
SCNAs:SCNBs [plasma membrane] (Homo sapiens)
SCNBs [plasma membrane] (Homo sapiens)
SCN4B [plasma membrane] (Homo sapiens)
Muscle contraction (Homo sapiens)
Cardiac conduction (Homo sapiens)
Phase 0 - rapid depolarisation (Homo sapiens)
SCNAs:SNCBs transport Na+ from extracellular region to cytosol (Homo sapiens)
SCNAs:SCNBs [plasma membrane] (Homo sapiens)
SCNBs [plasma membrane] (Homo sapiens)
SCN4B [plasma membrane] (Homo sapiens)
Sensory Perception (Homo sapiens)
Sensory perception of taste (Homo sapiens)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Homo sapiens)
SCN2A:SCN1B,2B,4B transports Na+ from the extracellular region to the cytosol (Homo sapiens)
SCN2A:SCN1B,2B,4B [plasma membrane] (Homo sapiens)
SCN1B,2B,4B [plasma membrane] (Homo sapiens)
SCN4B [plasma membrane] (Homo sapiens)
SCN3A:SCN2B,4B transports Na+ from the extracellular region to the cytosol (Homo sapiens)
SCN3A:SCN2B,4B [plasma membrane] (Homo sapiens)
SCN2B,4B [plasma membrane] (Homo sapiens)
SCN4B [plasma membrane] (Homo sapiens)
SCN9A:SCN1B,2B,4B transports Na+ from the extracellular region to the cytosol (Homo sapiens)
SCN9A:SCN1B,2B,4B [plasma membrane] (Homo sapiens)
SCN1B,2B,4B [plasma membrane] (Homo sapiens)
SCN4B [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8IWT1 SCN4B
Gene Names
SCN4B
Chain
signal peptide:1-30, chain:31-228
Reference Genes
BioGPS Gene:6330 SCN4B
COSMIC (genes):SCN4B SCN4B
CTD Gene:6330 SCN4B
dbSNP Gene:6330 SCN4B
ENSEMBL:ENSG00000177098 SCN4B
ENSEMBL_homo_sapiens_GENE:ENSG00000177098.9 SCN4B
HGNC:10592 SCN4B
KEGG Gene (Homo sapiens):6330 SCN4B
Monarch:6330 SCN4B
NCBI Gene:6330 SCN4B
OMIM:608256 SCN4B
UCSC:Q8IWT1 SCN4B
Reference Transcript
RefSeq:NM_174934.3 SCN4B
RefSeq:NM_001142348.1 SCN4B
RefSeq:NM_001142349.1 SCN4B
Other Identifiers
11755649_a_at
16744949
236359_PM_at
236359_at
3393623
3393624
3393625
3393626
3393627
3393629
3393630
3393631
3393632
3393637
3393638
3393639
53687_at
6330
7952004
A_23_P303833
GE533860
GO:0001518
GO:0003012
GO:0003013
GO:0005215
GO:0005248
GO:0005272
GO:0005515
GO:0005886
GO:0006811
GO:0006814
GO:0010765
GO:0014704
GO:0016020
GO:0017080
GO:0019228
GO:0023052
GO:0034220
GO:0034702
GO:0035725
GO:0044325
GO:0050877
GO:0051649
GO:0055085
GO:0060048
GO:0060307
GO:0086002
GO:0086006
GO:0086012
GO:0086016
GO:0086091
GO:0098772
GO:2000649
HMNXSV003050032
Hs.65239.0.A1_3p_at
ILMN_1695947
PH_hs_0004007
TC11002342.hg
TC11003372.hg
Participates
as a candidate of
SCN2B,4B [plasma membrane] (Homo sapiens)
SCN1B,2B,4B [plasma membrane] (Homo sapiens)
SCNBs [plasma membrane] (Homo sapiens)
Inferred To
SCN4B [plasma membrane]
(Bos taurus)
Cross References
RefSeq
NP_001135821.1
,
NP_777594.1
,
NP_001135820.1
OpenTargets
ENSG00000177098
HPA
ENSG00000177098-SCN4B
GeneCards
Q8IWT1
Ensembl
ENST00000324727
,
ENSP00000436343
,
ENSP00000322460
,
ENSG00000177098
,
ENST00000529878
PRO
Q8IWT1
Pharos - Targets
Q8IWT1
Orphanet
17441
HMDB Protein
HMDBP09085
PDB
6VSV
,
4MZ2
,
4MZ3
,
5XAW
,
7DTD
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O95070 YIF1A
1
YIF1A [endoplasmic reticulum membrane]
(R-HSA-535599)
0.556
3
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