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ASIC4 [plasma membrane]
Stable Identifier
R-HSA-2671913
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Acid-sensing ion channel 4, ASIC4_HUMAN
Locations in the PathwayBrowser
Expand all
Transport of small molecules (Homo sapiens)
Ion channel transport (Homo sapiens)
Stimuli-sensing channels (Homo sapiens)
ASIC trimers:H+ transport extracellular Na+ to cytosol (Homo sapiens)
ASIC4 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q96FT7 ASIC4
Gene Names
ASIC4, ACCN4
Chain
chain:1-539
Reference Genes
COSMIC (genes):ASIC4 ASIC4
dbSNP Gene:55515 ASIC4
ENSEMBL:ENSG00000072182 ASIC4
This entity regulates
Negatively
ASIC trimers:H+ transport extracellular Na+ to cytosol
(Homo sapiens)
Inferred To
ppk29 [plasma membrane]
(Drosophila melanogaster)
del-5 [plasma membrane]
(Caenorhabditis elegans)
ppk16 [plasma membrane]
(Drosophila melanogaster)
ppk23 [plasma membrane]
(Drosophila melanogaster)
acd-1 [plasma membrane]
(Caenorhabditis elegans)
ppk [plasma membrane]
(Drosophila melanogaster)
ppk10 [plasma membrane]
(Drosophila melanogaster)
ppk5 [plasma membrane]
(Drosophila melanogaster)
ppk11 [plasma membrane]
(Drosophila melanogaster)
ppk31 [plasma membrane]
(Drosophila melanogaster)
ppk24 [plasma membrane]
(Drosophila melanogaster)
ppk17 [plasma membrane]
(Drosophila melanogaster)
ppk25 [plasma membrane]
(Drosophila melanogaster)
ppk6 [plasma membrane]
(Drosophila melanogaster)
acd-2 [plasma membrane]
(Caenorhabditis elegans)
ppk15 [plasma membrane]
(Drosophila melanogaster)
Asic4 [plasma membrane]
(Mus musculus)
Asic4 [plasma membrane]
(Rattus norvegicus)
ppk30 [plasma membrane]
(Drosophila melanogaster)
Nach [plasma membrane]
(Drosophila melanogaster)
ppk20 [plasma membrane]
(Drosophila melanogaster)
ASIC4 [plasma membrane]
(Bos taurus)
ASIC4 [plasma membrane]
(Canis familiaris)
ASIC4 [plasma membrane]
(Gallus gallus)
ASIC4 [plasma membrane]
(Sus scrofa)
del-7 [plasma membrane]
(Caenorhabditis elegans)
flr-1 [plasma membrane]
(Caenorhabditis elegans)
rpk [plasma membrane]
(Drosophila melanogaster)
ppk19 [plasma membrane]
(Drosophila melanogaster)
ppk26 [plasma membrane]
(Drosophila melanogaster)
ppk7 [plasma membrane]
(Drosophila melanogaster)
ppk13 [plasma membrane]
(Drosophila melanogaster)
del-8 [plasma membrane]
(Caenorhabditis elegans)
ppk8 [plasma membrane]
(Drosophila melanogaster)
acd-3 [plasma membrane]
(Caenorhabditis elegans)
ppk21 [plasma membrane]
(Drosophila melanogaster)
asic4a [plasma membrane]
(Danio rerio)
ppk14 [plasma membrane]
(Drosophila melanogaster)
del-10 [plasma membrane]
(Caenorhabditis elegans)
ppk27 [plasma membrane]
(Drosophila melanogaster)
ppk12 [plasma membrane]
(Drosophila melanogaster)
Homologues of ASIC4 [plasma membrane]
(Caenorhabditis elegans)
Homologues of ASIC4 [plasma membrane]
(Drosophila melanogaster)
del-9 [plasma membrane]
(Caenorhabditis elegans)
ppk9 [plasma membrane]
(Drosophila melanogaster)
ppk22 [plasma membrane]
(Drosophila melanogaster)
ppk18 [plasma membrane]
(Drosophila melanogaster)
ppk28 [plasma membrane]
(Drosophila melanogaster)
acd-4 [plasma membrane]
(Caenorhabditis elegans)
delm-2 [plasma membrane]
(Caenorhabditis elegans)
asic4 [plasma membrane]
(Xenopus tropicalis)
acd-5 [plasma membrane]
(Caenorhabditis elegans)
delm-1 [plasma membrane]
(Caenorhabditis elegans)
ppk3 [plasma membrane]
(Drosophila melanogaster)
Interactors (12)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P32243-2 OTX2
0.556
3
UniProt:Q8IWB1 IPRI
0.527
3
UniProt:Q9NUQ7 UFSP2
0.527
2
UniProt:Q9H0V9 LMAN2L
3
LMAN2L [endoplasmic reticulum membrane]
(R-HSA-5689469)
LMAN2L [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-5689834)
LMAN2L [ER to Golgi transport vesicle membrane]
(R-HSA-5689832)
0.527
2
UniProt:Q8WZA1 POMGNT1
6
POMGNT1 [Golgi membrane]
(R-HSA-5617040)
POMGNT1 S550N [Golgi membrane]
(R-HSA-5617094)
POMGNT1 R605Vfs*29 [Golgi membrane]
(R-HSA-5617081)
POMGNT1 R63* [Golgi membrane]
(R-HSA-5617033)
POMGNT1 W475* [Golgi membrane]
(R-HSA-5617097)
POMGNT1 P493R [Golgi membrane]
(R-HSA-5617048)
0.527
3
UniProt:Q6ZNB6 NFXL1
0.527
2
UniProt:Q96IV0 NGLY1
1
NGLY1 [cytosol]
(R-HSA-8850591)
0.527
2
UniProt:Q5SWX8 ODR4
0.527
2
UniProt:Q9UK22 FBXO2
1
FBXO2 [cytosol]
(R-HSA-976044)
0.527
3
UniProt:Q86X29 LSR
1
LSR [plasma membrane]
(R-HSA-8933138)
0.527
2
UniProt:Q9UBV2 SEL1L
1
SEL1L [endoplasmic reticulum membrane]
(R-HSA-1911545)
0.527
2
UniProt:Q9HD20 ATP13A1
1
ATP13A1 [endoplasmic reticulum membrane]
(R-HSA-939749)
0.527
2
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