Reactome | KCNJ11 [plasma membrane]

KCNJ11 [plasma membrane]

Stable Identifier

R-HSA-265561

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Potassium Channel Kir6.2

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q14654 KCNJ11

Gene Names

KCNJ11

Chain

chain:1-390

Reference Genes

BioGPS Gene:3767 KCNJ11

COSMIC (genes):KCNJ11 KCNJ11

CTD Gene:3767 KCNJ11

dbSNP Gene:3767 KCNJ11

ENSEMBL:ENSG00000187486 KCNJ11

HGNC:6257 KCNJ11

KEGG:hsa:3767 KCNJ11

Monarch:3767 KCNJ11

NCBI Gene:3767 KCNJ11

OMIM:600937 KCNJ11

UCSC:Q14654 KCNJ11

Reference Transcript

Other Identifiers

11734293_a_at

11734294_at

11748661_a_at

16736268

231740_PM_at

231740_at

3364859

3364870

3364871

3364872

3364873

3364874

3364875

3364876

3364877

3767

67681_at

68911_at

7946853

A_23_P1973

D50582_at

GE80922

GO:0001508

GO:0001666

GO:0001669

GO:0002931

GO:0003229

GO:0005215

GO:0005242

GO:0005249

GO:0005515

GO:0005524

GO:0005635

GO:0005737

GO:0005768

GO:0005886

GO:0005975

GO:0006006

GO:0006813

GO:0006915

GO:0006950

GO:0008092

GO:0008282

GO:0008340

GO:0009410

GO:0012501

GO:0014704

GO:0015272

GO:0016020

GO:0019829

GO:0030315

GO:0030506

GO:0030673

GO:0030955

GO:0031072

GO:0031410

GO:0031669

GO:0032355

GO:0033198

GO:0033574

GO:0034220

GO:0034702

GO:0034765

GO:0042383

GO:0042391

GO:0042734

GO:0043025

GO:0043226

GO:0044325

GO:0046676

GO:0048856

GO:0050796

GO:0050877

GO:0055085

GO:0061762

GO:0070852

GO:0071316

GO:0071333

GO:0071356

GO:0071805

GO:0098655

GO:0098662

GO:0098978

GO:0099505

GO:0099508

GO:0140657

GO:1903078

GO:1904638

GO:1990573

HMNXSV003017071

Hs.248141.0.S1_3p_at

ILMN_1699057

PH_hs_0032311

TC11001456.hg

Participates

as a member of

ATP sensitive Potassium channels [plasma membrane] (Homo sapiens)

as a component of

Inferred To

Homologues of KCNJ11 [plasma membrane] (Drosophila melanogaster)

KCNJ11 [plasma membrane] (Bos taurus)

KCNJ11 [plasma membrane] (Canis familiaris)

KCNJ11 [plasma membrane] (Gallus gallus)

KCNJ11 [plasma membrane] (Sus scrofa)

kcnj21 [plasma membrane] (Xenopus tropicalis)

Irk1 [plasma membrane] (Drosophila melanogaster)

Irk3 [plasma membrane] (Drosophila melanogaster)

Irk2 [plasma membrane] (Drosophila melanogaster)

Kcnj11 [plasma membrane] (Mus musculus)

Kcnj11 [plasma membrane] (Rattus norvegicus)

Cross References

Guide to Pharmacology - Targets

442

ENSEMBL

ENST00000339994, ENSP00000434755, ENSP00000506780, ENST00000528731, ENST00000682764, ENSP00000345708, ENSP00000508090, ENST00000682350

OpenTargets

ENSG00000187486

HPA

ENSG00000187486-KCNJ11

ZINC target

Q14654

PRO

Q14654

Pharos - Targets

Q14654

Orphanet

KCNJ11

HMDB Protein

HMDBP02918

PDB

6C3O, 7S61, 7S60, 7S5T, 6C3P, 7S5X, 7S5Z, 7S5Y

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8WTR4 GDPD5	1	GDPD5 [endoplasmic reticulum membrane] (R-HSA-6814136)	0.527	2