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SEC61G [endoplasmic reticulum membrane]
Stable Identifier
R-HSA-265003
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum membrane
Synonyms
SEC61 gamma
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Translation (Homo sapiens)
SRP-dependent cotranslational protein targeting to membrane (Homo sapiens)
Signal peptidase hydrolyzes signal peptide from ribosome-associated nascent protein (Homo sapiens)
cleaved polypeptide:Translocon [endoplasmic reticulum membrane] (Homo sapiens)
Translocon:TRAP [endoplasmic reticulum membrane] (Homo sapiens)
SEC61 translocon [endoplasmic reticulum membrane] (Homo sapiens)
SEC61G [endoplasmic reticulum membrane] (Homo sapiens)
polypeptide+signal:Translocon [endoplasmic reticulum membrane] (Homo sapiens)
Translocon:TRAP [endoplasmic reticulum membrane] (Homo sapiens)
SEC61 translocon [endoplasmic reticulum membrane] (Homo sapiens)
SEC61G [endoplasmic reticulum membrane] (Homo sapiens)
Signal-containing nascent peptide translocates to endoplasmic reticulum (Homo sapiens)
Translocon:TRAP [endoplasmic reticulum membrane] (Homo sapiens)
SEC61 translocon [endoplasmic reticulum membrane] (Homo sapiens)
SEC61G [endoplasmic reticulum membrane] (Homo sapiens)
polypeptide+signal:Translocon [endoplasmic reticulum membrane] (Homo sapiens)
Translocon:TRAP [endoplasmic reticulum membrane] (Homo sapiens)
SEC61 translocon [endoplasmic reticulum membrane] (Homo sapiens)
SEC61G [endoplasmic reticulum membrane] (Homo sapiens)
Protein localization (Homo sapiens)
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane (Homo sapiens)
Tail-anchored protein:ASNA1:ADP:WRB:CAMLG dissociates yielding Tail-anchored protein in the endoplasmic reticulum membrane (Homo sapiens)
Tail-anchored proteins [endoplasmic reticulum membrane] (Homo sapiens)
SEC61G [endoplasmic reticulum membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P60059 SEC61G
Gene Names
SEC61G
Chain
chain:1-68
Reference Genes
BioGPS Gene:23480 SEC61G
COSMIC (genes):SEC61G SEC61G
CTD Gene:23480 SEC61G
dbSNP Gene:23480 SEC61G
ENSEMBL:ENSG00000132432 SEC61G
ENSEMBL_homo_sapiens_GENE:ENSG00000132432.14 SEC61G
HGNC:18277 SEC61G
KEGG Gene (Homo sapiens):23480 SEC61G
Monarch:23480 SEC61G
NCBI Gene:23480 SEC61G
OMIM:609215 SEC61G
UCSC:P60059 SEC61G
Reference Transcript
RefSeq:NM_001012456.1 SEC61G
RefSeq:NM_014302.3 SEC61G
Other Identifiers
11716223_a_at
17057884
203484_PM_at
203484_at
23480
3051400
3051405
3051407
3051409
3051410
3051411
39169_at
8139706
A_23_P71241
GE61207
GO:0005215
GO:0005515
GO:0005783
GO:0005789
GO:0005829
GO:0006605
GO:0006886
GO:0008320
GO:0015031
GO:0016020
GO:0031204
GO:0043022
GO:0043226
GO:0045047
GO:0055085
GO:0071261
HMNXSV003055707
ILMN_1787026
ILMN_2367020
PH_hs_0001028
g7657545_3p_at
Participates
as a member of
Tail-anchored proteins [endoplasmic reticulum membrane] (Homo sapiens)
as a component of
SEC61 translocon [endoplasmic reticulum membrane] (Homo sapiens)
Other forms of this molecule
SEC61G [phagocytic vesicle membrane]
SEC61G [cytosol]
Cross References
RefSeq
NP_001012474.1
,
NP_055117.1
OpenTargets
ENSG00000132432
HPA
ENSG00000132432-SEC61G
GeneCards
P60059
Ensembl
ENSP00000341538
,
ENST00000352861
,
ENSP00000378906
,
ENSP00000409884
,
ENST00000395535
,
ENST00000415949
,
ENSG00000132432
,
ENST00000450622
,
ENSP00000388337
PRO
P60059
Pharos - Targets
P60059
PDB
8DNX
,
8DO1
,
8DNZ
,
8DNW
,
8OJ0
,
8DO2
,
8B6L
,
8DNV
,
8OJ8
,
8DO3
,
8DNY
,
6W6L
,
8DO0
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q96BA8 CREB3L1
7
CREB3L1 [Golgi membrane]
(R-HSA-8874155)
CREB3L1(427-519) [Golgi membrane]
(R-HSA-8874139)
CREB3L1(1-426) [Golgi membrane]
(R-HSA-8874153)
CREB3L1 [endoplasmic reticulum membrane]
(R-HSA-8874157)
CREB3L1(1-375) [cytosol]
(R-HSA-8874215)
CREB3L1(376-426) [Golgi membrane]
(R-HSA-8874213)
CREB3L1(1-375) [nucleoplasm]
(R-HSA-8874222)
0.556
5
UniProt:P11686 SFTPC
9
pro-SFTPC P115L [endoplasmic reticulum membrane]
(R-HSA-5688352)
pro-SFTPC P30L [endoplasmic reticulum membrane]
(R-HSA-5688365)
pro-SFTPC [endoplasmic reticulum membrane]
(R-HSA-5683842)
pro-SFTPC [multivesicular body lumen]
(R-HSA-5685298)
SFTPC [extracellular region]
(R-HSA-5683685)
SFTPC [clathrin-coated endocytic vesicle]
(R-HSA-5686342)
SFTPC [lamellar body]
(R-HSA-5683717)
SFTPC(24-58) [multivesicular body lumen]
(R-HSA-5685899)
SFTPC(59-197) [multivesicular body lumen]
(R-HSA-5685871)
0.556
3
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