SREBP1A,2 binds the SQLE promoter

Stable Identifier
R-HSA-2426151
Type
Reaction
Species
Homo sapiens
Compartment
Synonyms
SREBF1A,2 binds the SQLE promoter
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Summation

SREBP1A (SREBF1A) or SREBP2 binds and transactivates the promoter of the SQLE gene (Reed et al. 2008). The promoter also contains a consensus binding site for NF-Y (Nagai et al. 2002).

Literature References
PubMed ID Title Journal Year
12083769 SREBP-2 and NF-Y are involved in the transcriptional regulation of squalene epoxidase

Nagai, M, Sakakibara, J, Nakamura, Y, Gejyo, F, Ono, T

Biochem Biophys Res Commun 2002
18559965 Microarray analyses of SREBP-1a and SREBP-1c target genes identify new regulatory pathways in muscle

Rome, S, Lecomte, V, Meugnier, E, Rieusset, J, Debard, C, Euthine, V, Vidal, H, Lefai, E

Physiol Genomics 2008
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