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3,4-Hyp 5-Gal-Hyl-collagen alpha-2(XI) chain [extracellular region]
Stable Identifier
R-HSA-2192871
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
COL11A2, COBA2_HUMAN
Locations in the PathwayBrowser
Expand all
Extracellular matrix organization (Homo sapiens)
Collagen formation (Homo sapiens)
Assembly of collagen fibrils and other multimeric structures (Homo sapiens)
Collagen XI cross-links with collagen II (Homo sapiens)
Collagen type XI fibril [extracellular region] (Homo sapiens)
Tropocollagen type XI [extracellular region] (Homo sapiens)
Collagen alpha-2(XI) chains [extracellular region] (Homo sapiens)
3,4-Hyp 5-Gal-Hyl-collagen alpha-2(XI) chain [extracellular region] (Homo sapiens)
Collagen type XI fibril:Collagen type II fibril [extracellular region] (Homo sapiens)
Collagen type XI fibril [extracellular region] (Homo sapiens)
Tropocollagen type XI [extracellular region] (Homo sapiens)
Collagen alpha-2(XI) chains [extracellular region] (Homo sapiens)
3,4-Hyp 5-Gal-Hyl-collagen alpha-2(XI) chain [extracellular region] (Homo sapiens)
Formation of collagen fibres (Homo sapiens)
Collagen fibres [extracellular region] (Homo sapiens)
Collagen type XI fibre [extracellular region] (Homo sapiens)
Collagen type XI fibril [extracellular region] (Homo sapiens)
Tropocollagen type XI [extracellular region] (Homo sapiens)
Collagen alpha-2(XI) chains [extracellular region] (Homo sapiens)
3,4-Hyp 5-Gal-Hyl-collagen alpha-2(XI) chain [extracellular region] (Homo sapiens)
Collagen fibrils [extracellular region] (Homo sapiens)
Collagen type XI fibril [extracellular region] (Homo sapiens)
Tropocollagen type XI [extracellular region] (Homo sapiens)
Collagen alpha-2(XI) chains [extracellular region] (Homo sapiens)
3,4-Hyp 5-Gal-Hyl-collagen alpha-2(XI) chain [extracellular region] (Homo sapiens)
Formation of collagen fibrils (Homo sapiens)
Collagen fibrils [extracellular region] (Homo sapiens)
Collagen type XI fibril [extracellular region] (Homo sapiens)
Tropocollagen type XI [extracellular region] (Homo sapiens)
Collagen alpha-2(XI) chains [extracellular region] (Homo sapiens)
3,4-Hyp 5-Gal-Hyl-collagen alpha-2(XI) chain [extracellular region] (Homo sapiens)
Tropocollagens [extracellular region] (Homo sapiens)
Tropocollagen type XI [extracellular region] (Homo sapiens)
Collagen alpha-2(XI) chains [extracellular region] (Homo sapiens)
3,4-Hyp 5-Gal-Hyl-collagen alpha-2(XI) chain [extracellular region] (Homo sapiens)
Collagen biosynthesis and modifying enzymes (Homo sapiens)
Removal of fibrillar collagen C-propeptides (Homo sapiens)
Tropocollagens [extracellular region] (Homo sapiens)
Tropocollagen type XI [extracellular region] (Homo sapiens)
Collagen alpha-2(XI) chains [extracellular region] (Homo sapiens)
3,4-Hyp 5-Gal-Hyl-collagen alpha-2(XI) chain [extracellular region] (Homo sapiens)
Degradation of the extracellular matrix (Homo sapiens)
Collagen degradation (Homo sapiens)
Collagen type XI degradation by MMP1,2,3,9 (Homo sapiens)
Collagen type XI fibril [extracellular region] (Homo sapiens)
Tropocollagen type XI [extracellular region] (Homo sapiens)
Collagen alpha-2(XI) chains [extracellular region] (Homo sapiens)
3,4-Hyp 5-Gal-Hyl-collagen alpha-2(XI) chain [extracellular region] (Homo sapiens)
Non-integrin membrane-ECM interactions (Homo sapiens)
DDR1 binds collagen type I, II, III, IV, V, XI fibrils (Homo sapiens)
Collagen type I, II, III, IV, V, XI fibrils [extracellular region] (Homo sapiens)
Collagen type XI fibril [extracellular region] (Homo sapiens)
Tropocollagen type XI [extracellular region] (Homo sapiens)
Collagen alpha-2(XI) chains [extracellular region] (Homo sapiens)
3,4-Hyp 5-Gal-Hyl-collagen alpha-2(XI) chain [extracellular region] (Homo sapiens)
DDR1 dimer:Collagen type I, II, III, IV, V, XI fibrils [plasma membrane] (Homo sapiens)
Collagen type I, II, III, IV, V, XI fibrils [extracellular region] (Homo sapiens)
Collagen type XI fibril [extracellular region] (Homo sapiens)
Tropocollagen type XI [extracellular region] (Homo sapiens)
Collagen alpha-2(XI) chains [extracellular region] (Homo sapiens)
3,4-Hyp 5-Gal-Hyl-collagen alpha-2(XI) chain [extracellular region] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by MET (Homo sapiens)
MET promotes cell motility (Homo sapiens)
MET activates PTK2 signaling (Homo sapiens)
PTK2 binds activated MET (Homo sapiens)
Integrin alpha2beta1,alpha3:beta1:(collagen,laminin,fibronectin) [plasma membrane] (Homo sapiens)
Collagen, laminin, fibronectin [extracellular region] (Homo sapiens)
Collagen fibres [extracellular region] (Homo sapiens)
Collagen type XI fibre [extracellular region] (Homo sapiens)
Collagen type XI fibril [extracellular region] (Homo sapiens)
Tropocollagen type XI [extracellular region] (Homo sapiens)
Collagen alpha-2(XI) chains [extracellular region] (Homo sapiens)
3,4-Hyp 5-Gal-Hyl-collagen alpha-2(XI) chain [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:P13942 COL11A2
Gene Names
COL11A2
Chain
signal peptide:1-27, chain:28-1736, propeptide:1501-1736
Reference Genes
BioGPS Gene:1302 COL11A2
COSMIC (genes):COL11A2 COL11A2
CTD Gene:1302 COL11A2
dbSNP Gene:1302 COL11A2
ENSEMBL:ENSG00000204248 COL11A2
HGNC:2187 COL11A2
KEGG:hsa:1302 COL11A2
Monarch:1302 COL11A2
NCBI Gene:1302 COL11A2
OMIM:120290 COL11A2
UCSC:P13942 COL11A2
Reference Transcript
RefSeq:NM_001163771.1 COL11A2
RefSeq:XM_017010250.1 COL11A2
RefSeq:NM_080680.2 COL11A2
RefSeq:NM_080681.2 COL11A2
Other Identifiers
1026_s_at
1027_at
11743769_a_at
11744676_a_at
11755914_a_at
1302
17018053
17029860
17032547
17034867
17037347
17040053
17042562
213870_PM_at
213870_at
216993_PM_s_at
216993_s_at
2950368
2950389
2950390
2950391
2950392
2950393
2950394
2950396
2950397
2950398
2950399
2950400
2950401
2950402
2950403
2950404
2950405
2950406
2950407
2950408
2950409
2950410
2950412
2950413
2950414
2950415
2950416
2950417
2950418
2950419
2950420
2950421
2950422
2950423
2950424
2950425
2950426
2950427
2950429
2950430
2950431
2950432
2950433
2950434
2950435
2950437
2950438
2950440
2950441
2950442
2950443
2950444
2950445
2950446
2950447
2950448
2950449
2950450
2950451
2950452
2950453
2950454
2950455
2950456
2950458
2950459
2950460
2950461
2950462
2950463
2950465
2950466
2950467
2950468
2950469
2950470
2950471
2950472
2950473
3002979
41652_at
65322_at
8125568
8178897
8180105
A_33_P3216442
A_33_P3216448
GE56078
GO:0001501
GO:0001649
GO:0001894
GO:0002062
GO:0005198
GO:0005201
GO:0005515
GO:0005576
GO:0005581
GO:0005592
GO:0005615
GO:0005788
GO:0005840
GO:0007605
GO:0008201
GO:0030020
GO:0030154
GO:0030198
GO:0030199
GO:0030312
GO:0030674
GO:0031012
GO:0043226
GO:0046872
GO:0048705
GO:0048856
GO:0050877
GO:0051216
GO:0060021
GO:0060023
GO:0060090
GO:0062023
HMNXSV003006397
HMNXSV003055751
Hs.121509.0.S1_3p_at
Hs.121509.1.S1_3p_a_at
ILMN_1748166
ILMN_2311456
PH_hs_0024520
TC06001579.hg
TC6_cox_hap2000203.hg
TC6_dbb_hap3000189.hg
TC6_mann_hap4000171.hg
TC6_mcf_hap5000178.hg
TC6_qbl_hap6000191.hg
TC6_ssto_hap7000173.hg
U41068_cds2_s_at
Participates
as a member of
Collagen alpha-2(XI) chains [extracellular region] (Homo sapiens)
Other forms of this molecule
3x4Hyp-3Hyp-GlcGalHyl-COL11A2 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-GalHyl-COL11A2 [endoplasmic reticulum lumen]
3x4Hyp-GalHyl-COL11A2 [endoplasmic reticulum lumen]
GalHyl-COL11A2 [endoplasmic reticulum lumen]
GlcGalHyl-COL11A2 [endoplasmic reticulum lumen]
3x4Hyp-GlcGalHyl-COL11A2 [endoplasmic reticulum lumen]
COL11A2 [endoplasmic reticulum lumen]
3x4Hyp-COL11A2 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-COL11A2 [endoplasmic reticulum lumen]
3x4Hyp-5Hyl-COL11A2 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-5Hyl-COL11A2 [endoplasmic reticulum lumen]
5Hyl-COL11A2 [endoplasmic reticulum lumen]
3x4Hyp-GlcGalHyl-COL11A2 [extracellular region]
3x4Hyp-3Hyp-COL11A2 [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL11A2 [extracellular region]
GalHyl-COL11A2 [extracellular region]
3x4Hyp-5Hyl-COL11A2 [extracellular region]
GlcGalHyl-COL11A2(28-1736) [extracellular region]
GalHyl-COL11A2(?-1736) [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL11A2(28-1736) [extracellular region]
3x4Hyp-GalHyl-COL11A2(28-1736) [extracellular region]
3x4Hyp-5Hyl-COL11A2(?-1736) [extracellular region]
5Hyl-COL11A2(28-1736) [extracellular region]
3x4Hyp-3Hyp-COL11A2(?-1736) [extracellular region]
3,4-Hyp Glu-Gal-Hyl-collagen alpha-2(XI) chain [extracellular region]
3,4-hydroxyprolyl collagen alpha-2(XI) chain [extracellular region]
5-Gal-Hyl collagen alpha-2(XI) chain [extracellular region]
4-Hyp Glu-Gal-Hyl collagen alpha-2(XI) chain [extracellular region]
5-hydroxylysyl-collagen alpha-2(XI) chain [extracellular region]
4-hydroxyprolyl collagen alpha-2(XI) chain [extracellular region]
Glu-Gal-Hyl collagen alpha-2(XI) chain [extracellular region]
4-Hyp 5-Gal-Hyl collagen alpha-2(XI) chain [extracellular region]
4-Hyp 5-Hyl collagen alpha-2(XI) chain [extracellular region]
Collagen alpha-2(XI) chain [extracellular region]
3,4-Hyp 5-Hyl-collagen alpha-2(XI) chain [extracellular region]
4-Hyp Glu-Gal-Hyl collagen alpha-2(XI) chain C-term fragment [extracellular region]
Glu-Gal-Hyl collagen alpha-2(XI) chain N-term fragment [extracellular region]
5-hydroxylysyl-collagen alpha-2(XI) chain C-term fragment [extracellular region]
4-Hyp Glu-Gal-Hyl collagen alpha-2(XI) chain N-term fragment [extracellular region]
5-Gal-Hyl collagen alpha-2(XI) chain N-term fragment [extracellular region]
3,4-Hyp Glu-Gal-Hyl-collagen alpha-2(XI) chain C-term fragment [extracellular region]
3,4-hydroxyprolyl collagen alpha-2(XI) chain N-term fragment [extracellular region]
3,4-Hyp 5-Hyl-collagen alpha-2(XI) chain C-term fragment [extracellular region]
3,4-Hyp 5-Gal-Hyl-collagen alpha-2(XI) chain C-term fragment [extracellular region]
5-Gal-Hyl collagen alpha-2(XI) chain C-term fragment [extracellular region]
3,4-Hyp 5-Hyl-collagen alpha-2(XI) chain N-term fragment [extracellular region]
4-Hyp 5-Gal-Hyl collagen alpha-2(XI) chain C-term fragment [extracellular region]
3,4-hydroxyprolyl collagen alpha-2(XI) chain C-term fragment [extracellular region]
Collagen alpha-2(XI) chain C-term fragment [extracellular region]
3,4-Hyp Glu-Gal-Hyl-collagen alpha-2(XI) chain N-term fragment [extracellular region]
Glu-Gal-Hyl collagen alpha-2(XI) chain C-term fragment [extracellular region]
4-Hyp 5-Hyl collagen alpha-2(XI) chain N-term fragment [extracellular region]
Collagen alpha-2(XI) chain N-term fragment [extracellular region]
4-hydroxyprolyl collagen alpha-2(XI) chain C-term fragment [extracellular region]
5-hydroxylysyl-collagen alpha-2(XI) chain N-term fragment [extracellular region]
4-Hyp 5-Gal-Hyl collagen alpha-2(XI) chain N-term fragment [extracellular region]
4-hydroxyprolyl collagen alpha-2(XI) chain N-term fragment [extracellular region]
3,4-Hyp 5-Gal-Hyl-collagen alpha-2(XI) chain N-term fragment [extracellular region]
4-Hyp 5-Hyl collagen alpha-2(XI) chain C-term fragment [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL11A2(28-1736) [extracellular region]
3x4Hyp-GlcGalHyl-COL11A2(?-1736) [extracellular region]
3x4Hyp-COL11A2(28-1736) [extracellular region]
COL11A2(28-1736) [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL11A2(?-1736) [extracellular region]
Inferred To
Col11a2 [extracellular region]
(Rattus norvegicus)
3,4-Hyp 5-Gal-Hyl-collagen alpha-2(XI) chain [extracellular region]
(Mus musculus)
COL11A2 [extracellular region]
(Bos taurus)
COL11A2 [extracellular region]
(Canis familiaris)
COL11A2 [extracellular region]
(Sus scrofa)
Modified Residues
Name
(2S,4R)-4-hydroxyproline at unknown position
PsiMod Name
(2S,4R)-4-hydroxyproline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline
Name
(2S,4R)-4-hydroxyproline at unknown position
PsiMod Name
(2S,4R)-4-hydroxyproline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline
Name
(2S,4R)-4-hydroxyproline at unknown position
PsiMod Name
(2S,4R)-4-hydroxyproline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline
Name
(2S,3S)-3-hydroxyproline at unknown position
PsiMod Name
(2S,3S)-3-hydroxyproline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to 3-hydroxy-L-proline.
Name
O5-galactosyl-L-hydroxylysine at unknown position
PsiMod Name
O5-galactosyl-L-hydroxylysine
PsiMod Definition
A protein modification that effectively converts an L-lysine residue to O5-galactosyl-L-hydroxylysine.
Cross References
OpenTargets
ENSG00000204248
ENSEMBL
ENSP00000372566
,
ENST00000395194
,
ENSP00000372565
,
ENSP00000449275
,
ENST00000452937
,
ENST00000549811
,
ENSP00000410284
,
ENSP00000378620
,
ENST00000551542
,
ENST00000447741
,
ENSP00000400813
,
ENST00000439039
,
ENST00000383088
,
ENST00000383087
,
ENSP00000406347
,
ENSP00000447864
HPA
ENSG00000204248-COL11A2
PRO
P13942
Pharos - Targets
P13942
GlyGen
P13942
Orphanet
COL11A2
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