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3x4Hyp-GlcGalHyl-COL8A2 [extracellular region]
Stable Identifier
R-HSA-2192744
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
4-Hyp Glu-Gal-Hyl collagen alpha-2(VIII) chain, COL8A2, CO8A2_HUMAN
Locations in the PathwayBrowser
Expand all
Extracellular matrix organization (Homo sapiens)
Collagen formation (Homo sapiens)
Assembly of collagen fibrils and other multimeric structures (Homo sapiens)
Formation of collagen networks (Homo sapiens)
Collagen networks [extracellular region] (Homo sapiens)
Collagen type VIII network [extracellular region] (Homo sapiens)
Tropocollagen type VIII [extracellular region] (Homo sapiens)
Collagen alpha-2(VIII) chains [extracellular region] (Homo sapiens)
3x4Hyp-GlcGalHyl-COL8A2 [extracellular region] (Homo sapiens)
Network forming tropocollagens [extracellular region] (Homo sapiens)
Tropocollagen type VIII [extracellular region] (Homo sapiens)
Collagen alpha-2(VIII) chains [extracellular region] (Homo sapiens)
3x4Hyp-GlcGalHyl-COL8A2 [extracellular region] (Homo sapiens)
Collagen biosynthesis and modifying enzymes (Homo sapiens)
Secretion of collagens (Homo sapiens)
Collagens and tropocollagens [extracellular region] (Homo sapiens)
Non-fibrillar collagens [extracellular region] (Homo sapiens)
Tropocollagen type VIII [extracellular region] (Homo sapiens)
Collagen alpha-2(VIII) chains [extracellular region] (Homo sapiens)
3x4Hyp-GlcGalHyl-COL8A2 [extracellular region] (Homo sapiens)
Degradation of the extracellular matrix (Homo sapiens)
Collagen degradation (Homo sapiens)
Collagen type VIII degradation by ELANE (Homo sapiens)
Collagen type VIII fibril [extracellular region] (Homo sapiens)
Tropocollagen type VIII [extracellular region] (Homo sapiens)
Collagen alpha-2(VIII) chains [extracellular region] (Homo sapiens)
3x4Hyp-GlcGalHyl-COL8A2 [extracellular region] (Homo sapiens)
Collagen type VIII degradation by MMP1 (Homo sapiens)
Collagen type VIII fibril [extracellular region] (Homo sapiens)
Tropocollagen type VIII [extracellular region] (Homo sapiens)
Collagen alpha-2(VIII) chains [extracellular region] (Homo sapiens)
3x4Hyp-GlcGalHyl-COL8A2 [extracellular region] (Homo sapiens)
Integrin cell surface interactions (Homo sapiens)
Collagen types III, IV, V, VI, VIII, IX, XVI bind integrins alpha1beta1 and alpha2beta1 (Homo sapiens)
Collagen types III, IV, V, VI, VIII, IX, XVI [extracellular region] (Homo sapiens)
Collagen type VIII fibril [extracellular region] (Homo sapiens)
Tropocollagen type VIII [extracellular region] (Homo sapiens)
Collagen alpha-2(VIII) chains [extracellular region] (Homo sapiens)
3x4Hyp-GlcGalHyl-COL8A2 [extracellular region] (Homo sapiens)
Collagen types III, IV, V, VI, VIII, IX, XVI:Integrins alpha1beta 1, alpha2beta1 [plasma membrane] (Homo sapiens)
Collagen types III, IV, V, VI, VIII, IX, XVI [extracellular region] (Homo sapiens)
Collagen type VIII fibril [extracellular region] (Homo sapiens)
Tropocollagen type VIII [extracellular region] (Homo sapiens)
Collagen alpha-2(VIII) chains [extracellular region] (Homo sapiens)
3x4Hyp-GlcGalHyl-COL8A2 [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:P25067 COL8A2
Gene Names
COL8A2
Chain
signal peptide:1-28, chain:29-703
Reference Genes
BioGPS Gene:1296 COL8A2
COSMIC (genes):COL8A2 COL8A2
CTD Gene:1296 COL8A2
dbSNP Gene:1296 COL8A2
ENSEMBL:ENSG00000171812 COL8A2
ENSEMBL_homo_sapiens_GENE:ENSG00000171812.13 COL8A2
HGNC:2216 COL8A2
KEGG Gene (Homo sapiens):1296 COL8A2
Monarch:1296 COL8A2
NCBI Gene:1296 COL8A2
OMIM:120252 COL8A2
UCSC:P25067 COL8A2
Reference Transcript
RefSeq:NM_001294347.1 COL8A2
RefSeq:NM_005202.3 COL8A2
Other Identifiers
11743667_at
11752994_a_at
1296
16685201
221900_PM_at
221900_at
2406576
2406578
2406580
2406581
2406582
2406583
2406584
2406585
2406586
2406587
2406588
2406589
2406594
2406595
2406596
52651_PM_at
52651_at
52652_g_at
60876_at
63943_at
7914880
A_24_P365975
A_33_P3297930
GE87831
GO:0001525
GO:0001935
GO:0005198
GO:0005201
GO:0005515
GO:0005576
GO:0005581
GO:0005604
GO:0005615
GO:0005783
GO:0005788
GO:0007155
GO:0030020
GO:0030198
GO:0030312
GO:0030674
GO:0031012
GO:0043226
GO:0048593
GO:0048856
GO:0060090
GO:0062023
GO:0098609
HMNXSV003015532
Hs.249239.0.S1_3p_at
Hs.249239.0.S1_3p_s_at
ILMN_1674050
ILMN_2102330
PH_hs_0017115
TC01002503.hg
Participates
as a member of
Collagen alpha-2(VIII) chains [extracellular region] (Homo sapiens)
Other forms of this molecule
3x4Hyp-GalHyl-COL8A2 [endoplasmic reticulum lumen]
GalHyl-COL8A2 [endoplasmic reticulum lumen]
3x4Hyp-GlcGalHyl-COL8A2 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-GalHyl-COL8A2 [endoplasmic reticulum lumen]
GlcGalHyl-COL8A2 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-GlcGalHyl-COL8A2 [endoplasmic reticulum lumen]
COL8A2 [endoplasmic reticulum lumen]
3x4Hyp-COL8A2 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-COL8A2 [endoplasmic reticulum lumen]
3x4Hyp-5Hyl-COL8A2 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-5Hyl-COL8A2 [endoplasmic reticulum lumen]
5Hyl-COL8A2 [endoplasmic reticulum lumen]
GlcGalHyl-COL8A2(?-703) [extracellular region]
3x4Hyp-GalHyl-COL8A2(?-703) [extracellular region]
3x4Hyp-GlcGalHyl-COL8A2(29-?) [extracellular region]
GalHyl-COL8A2(29-?) [extracellular region]
3x4Hyp-3Hyp-COL8A2(?-703) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL8A2(?-703) [extracellular region]
5Hyl-COL8A2(29-?) [extracellular region]
5Hyl-COL8A2(?-703) [extracellular region]
GalHyl-COL8A2(?-703) [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL8A2(?-703) [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL8A2(?-703) [extracellular region]
3x4Hyp-GalHyl-COL8A2(29-?) [extracellular region]
3x4Hyp-5Hyl-COL8A2(29-?) [extracellular region]
3x4Hyp-3Hyp-COL8A2(29-?) [extracellular region]
3x4Hyp-COL8A2(?-703) [extracellular region]
COL8A2(29-?) [extracellular region]
3x4Hyp-5Hyl-COL8A2(?-703) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL8A2(29-?) [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL8A2(29-?) [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL8A2(29-?) [extracellular region]
COL8A2(?-703) [extracellular region]
3x4Hyp-3Hyp-COL8A2 [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL8A2 [extracellular region]
GlcGalHyl-COL8A2 [extracellular region]
3x4Hyp-COL8A2 [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL8A2 [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL8A2 [extracellular region]
GalHyl-COL8A2 [extracellular region]
5Hyl-COL8A2 [extracellular region]
3x4Hyp-GalHyl-COL8A2 [extracellular region]
COL8A2 [extracellular region]
3x4Hyp-5Hyl-COL8A2 [extracellular region]
3x4Hyp-COL8A2(29-?) [extracellular region]
GlcGalHyl-COL8A2(29-?) [extracellular region]
3x4Hyp-GlcGalHyl-COL8A2(?-703) [extracellular region]
Inferred To
COL8A2 [extracellular region]
(Bos taurus)
COL8A2 [extracellular region]
(Canis familiaris)
COL8A2 [extracellular region]
(Sus scrofa)
col-99 [extracellular region]
(Caenorhabditis elegans)
Col8a2 [extracellular region]
(Mus musculus)
Col8a2 [extracellular region]
(Rattus norvegicus)
Mp [extracellular region]
(Drosophila melanogaster)
3x4Hyp-GlcGalHyl-COL8A2 [extracellular region]
(Gallus gallus)
Modified Residues
Name
(2S,4R)-4-hydroxyproline at unknown position
PsiMod Name
(2S,4R)-4-hydroxyproline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline
Name
(2S,4R)-4-hydroxyproline at unknown position
PsiMod Name
(2S,4R)-4-hydroxyproline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline
Name
(2S,4R)-4-hydroxyproline at unknown position
PsiMod Name
(2S,4R)-4-hydroxyproline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline
Name
O5-glucosylgalactosyl-L-hydroxylysine at unknown position
PsiMod Name
O5-glucosylgalactosyl-L-hydroxylysine
PsiMod Definition
A protein modification that effectively converts an L-lysine residue to O5-glucosylgalactosyl-L-hydroxylysine.
Cross References
RefSeq
NP_001281276.1
,
NP_005193.1
OpenTargets
ENSG00000171812
GeneCards
P25067
HPA
ENSG00000171812-COL8A2
Ensembl
ENST00000303143
,
ENSP00000380901
,
ENSG00000171812
,
ENSP00000305913
,
ENST00000397799
PRO
P25067
Pharos - Targets
P25067
Orphanet
15782
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