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3x4Hyp-3Hyp-5Hyl-COL23A1 [endoplasmic reticulum lumen]
Stable Identifier
R-HSA-2173215
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum lumen
Synonyms
3,4-Hyp 5-Hyl-collagen alpha-1(XXIII) chain, COL23A1, CONA1_HUMAN
Locations in the PathwayBrowser
Expand all
Extracellular matrix organization (Homo sapiens)
Collagen formation (Homo sapiens)
Collagen biosynthesis and modifying enzymes (Homo sapiens)
COLGALT1,COLGALT2 bind Lysyl hydroxylated collagen propeptides (Homo sapiens)
COLGALT1,COLGALT2:Lysyl hydroxylated collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
Lysyl hydroxylated collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
3,4-Hyp 5-Hyl collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-3Hyp-5Hyl-COL23A1 [endoplasmic reticulum lumen] (Homo sapiens)
Lysyl hydroxylated collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
3,4-Hyp 5-Hyl collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-3Hyp-5Hyl-COL23A1 [endoplasmic reticulum lumen] (Homo sapiens)
Collagen chain trimerization (Homo sapiens)
Association of procollagen type XXIII (Homo sapiens)
Alpha-1(XXIII) chains [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-3Hyp-5Hyl-COL23A1 [endoplasmic reticulum lumen] (Homo sapiens)
C-linked procollagen type XXIII trimer [endoplasmic reticulum lumen] (Homo sapiens)
Alpha-1(XXIII) chains [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-3Hyp-5Hyl-COL23A1 [endoplasmic reticulum lumen] (Homo sapiens)
Galactosylation of collagen propeptide hydroxylysines by PLOD3 (Homo sapiens)
PLOD3:Fe2+ dimer:Lysyl hydroxylated collagen propeptides [endoplasmic reticulum membrane] (Homo sapiens)
Lysyl hydroxylated collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
3,4-Hyp 5-Hyl collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-3Hyp-5Hyl-COL23A1 [endoplasmic reticulum lumen] (Homo sapiens)
Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2 (Homo sapiens)
COLGALT1,COLGALT2:Lysyl hydroxylated collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
Lysyl hydroxylated collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
3,4-Hyp 5-Hyl collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-3Hyp-5Hyl-COL23A1 [endoplasmic reticulum lumen] (Homo sapiens)
Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases (Homo sapiens)
Lysyl hydroxylases:Lysyl hydroxylated collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
Lysyl hydroxylated collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
3,4-Hyp 5-Hyl collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-3Hyp-5Hyl-COL23A1 [endoplasmic reticulum lumen] (Homo sapiens)
Lysyl hydroxylated collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
3,4-Hyp 5-Hyl collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-3Hyp-5Hyl-COL23A1 [endoplasmic reticulum lumen] (Homo sapiens)
PLOD3 binds Lysyl hydroxylated collagen propeptides (Homo sapiens)
Lysyl hydroxylated collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
3,4-Hyp 5-Hyl collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-3Hyp-5Hyl-COL23A1 [endoplasmic reticulum lumen] (Homo sapiens)
PLOD3:Fe2+ dimer:Lysyl hydroxylated collagen propeptides [endoplasmic reticulum membrane] (Homo sapiens)
Lysyl hydroxylated collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
3,4-Hyp 5-Hyl collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-3Hyp-5Hyl-COL23A1 [endoplasmic reticulum lumen] (Homo sapiens)
Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines (Homo sapiens)
Lysyl hydroxylases:Lysyl hydroxylated collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
Lysyl hydroxylated collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
3,4-Hyp 5-Hyl collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-3Hyp-5Hyl-COL23A1 [endoplasmic reticulum lumen] (Homo sapiens)
Procollagen triple helix formation (Homo sapiens)
Collagen and procollagen triple helices:Serpin H1 [endoplasmic reticulum lumen] (Homo sapiens)
Collagen and procollagen triple helices [endoplasmic reticulum lumen] (Homo sapiens)
Transmembrane collagens [endoplasmic reticulum lumen] (Homo sapiens)
Collagen type XXIII [endoplasmic reticulum lumen] (Homo sapiens)
Alpha-1(XXIII) chains [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-3Hyp-5Hyl-COL23A1 [endoplasmic reticulum lumen] (Homo sapiens)
Procollagen C-linked trimers [endoplasmic reticulum lumen] (Homo sapiens)
C-linked procollagen type XXIII trimer [endoplasmic reticulum lumen] (Homo sapiens)
Alpha-1(XXIII) chains [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-3Hyp-5Hyl-COL23A1 [endoplasmic reticulum lumen] (Homo sapiens)
Secretion of transmembrane collagens (Homo sapiens)
Transmembrane collagens [endoplasmic reticulum lumen] (Homo sapiens)
Collagen type XXIII [endoplasmic reticulum lumen] (Homo sapiens)
Alpha-1(XXIII) chains [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-3Hyp-5Hyl-COL23A1 [endoplasmic reticulum lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q86Y22 COL23A1
Gene Names
COL23A1
Chain
chain:1-540
Reference Genes
BioGPS Gene:91522 COL23A1
COSMIC (genes):COL23A1 COL23A1
CTD Gene:91522 COL23A1
dbSNP Gene:91522 COL23A1
ENSEMBL:ENSG00000050767 COL23A1
ENSEMBL_homo_sapiens_GENE:ENSG00000050767.18 COL23A1
HGNC:22990 COL23A1
KEGG Gene (Homo sapiens):91522 COL23A1
Monarch:91522 COL23A1
NCBI Gene:91522 COL23A1
OMIM:610043 COL23A1
UCSC:Q86Y22 COL23A1
Reference Transcript
RefSeq:NM_173465.3 COL23A1
Other Identifiers
11725021_at
17003530
229168_PM_at
229168_at
2889545
2889546
2889547
2889548
2889550
2889551
2889552
2889554
2889556
2889557
2889558
2889559
2889560
2889561
2889563
2889564
2889565
2889566
2889567
2889571
2889574
2889576
2889580
2889584
2889585
2889590
2889592
2889599
2889609
2889682
2889692
2889693
2889694
2889695
46106_at
8116195
91522
A_23_P387031
GE56718
GO:0005198
GO:0005515
GO:0005576
GO:0005581
GO:0005604
GO:0005615
GO:0005783
GO:0005788
GO:0005886
GO:0008201
GO:0009986
GO:0016020
GO:0030020
GO:0030198
GO:0030312
GO:0031012
GO:0042802
GO:0043226
GO:0062023
HMNXSV003020095
Hs.55407.0.S1_3p_at
Hs.55407.0.S1_3p_x_at
PH_hs_0024949
TC05002123.hg
Participates
as a member of
Alpha-1(XXIII) chains [endoplasmic reticulum lumen] (Homo sapiens)
as a candidate of
3,4-Hyp 5-Hyl collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
Other forms of this molecule
GalHyl-COL23A1 [endoplasmic reticulum lumen]
3x4Hyp-GlcGalHyl-COL23A1 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-GlcGalHyl-COL23A1 [endoplasmic reticulum lumen]
3x4Hyp-GalHyl-COL23A1 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-GalHyl-COL23A1 [endoplasmic reticulum lumen]
GlcGalHyl-COL23A1 [endoplasmic reticulum lumen]
COL23A1 [endoplasmic reticulum lumen]
3x4Hyp-COL23A1 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-COL23A1 [endoplasmic reticulum lumen]
3x4Hyp-5Hyl-COL23A1 [endoplasmic reticulum lumen]
5Hyl-COL23A1 [endoplasmic reticulum lumen]
3x4Hyp-GalHyl-COL23A1(?-540) [extracellular region]
COL23A1(?-540) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL23A1(?-540) [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL23A1(?-540) [extracellular region]
GlcGalHyl-COL23A1(?-540) [extracellular region]
3x4Hyp-3Hyp-COL23A1(?-540) [extracellular region]
3x4Hyp-COL23A1(?-540) [extracellular region]
3x4Hyp-5Hyl-COL23A1(?-540) [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL23A1(?-540) [extracellular region]
GalHyl-COL23A1(?-540) [extracellular region]
3x4Hyp-GlcGalHyl-COL23A1(?-540) [extracellular region]
5Hyl-COL23A1(?-540) [extracellular region]
GalHyl-COL23A1(1-?) [plasma membrane]
3x4Hyp-GlcGalHyl-COL23A1(1-?) [plasma membrane]
COL23A1(1-?) [plasma membrane]
3x4Hyp-3Hyp-5Hyl-COL23A1(1-?) [plasma membrane]
GlcGalHyl-COL23A1(1-?) [plasma membrane]
3x4Hyp-GalHyl-COL23A1 [plasma membrane]
3x4Hyp-3Hyp-COL23A1 [plasma membrane]
COL23A1 [plasma membrane]
3x4Hyp-3Hyp-5Hyl-COL23A1 [plasma membrane]
3x4Hyp-GlcGalHyl-COL23A1 [plasma membrane]
GalHyl-COL23A1 [plasma membrane]
GlcGalHyl-COL23A1 [plasma membrane]
5Hyl-COL23A1 [plasma membrane]
3x4Hyp-5Hyl-COL23A1 [plasma membrane]
3x4Hyp-3Hyp-GalHyl-COL23A1 [plasma membrane]
3x4Hyp-COL23A1 [plasma membrane]
3x4Hyp-3Hyp-GlcGalHyl-COL23A1 [plasma membrane]
3x4Hyp-COL23A1(1-?) [plasma membrane]
3x4Hyp-5Hyl-COL23A1(1-?) [plasma membrane]
3x4Hyp-GalHyl-COL23A1(1-?) [plasma membrane]
5Hyl-COL23A1(1-?) [plasma membrane]
3x4Hyp-3Hyp-GalHyl-COL23A1(1-?) [plasma membrane]
3x4Hyp-3Hyp-GlcGalHyl-COL23A1(1-?) [plasma membrane]
3x4Hyp-3Hyp-COL23A1(1-?) [plasma membrane]
Inferred To
Col23a1 [endoplasmic reticulum lumen]
(Mus musculus)
Col23a1 [endoplasmic reticulum lumen]
(Rattus norvegicus)
COL23A1 [endoplasmic reticulum lumen]
(Bos taurus)
COL23A1 [endoplasmic reticulum lumen]
(Canis familiaris)
COL23A1 [endoplasmic reticulum lumen]
(Sus scrofa)
Modified Residues
Name
(2S,4R)-4-hydroxyproline at unknown position
PsiMod Name
(2S,4R)-4-hydroxyproline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline
Name
(2S,4R)-4-hydroxyproline at unknown position
PsiMod Name
(2S,4R)-4-hydroxyproline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline
Name
(2S,4R)-4-hydroxyproline at unknown position
PsiMod Name
(2S,4R)-4-hydroxyproline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline
Name
(2S,3S)-3-hydroxyproline at unknown position
PsiMod Name
(2S,3S)-3-hydroxyproline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to 3-hydroxy-L-proline.
Name
(2S,5R)-5-hydroxylysine at unknown position
PsiMod Name
(2S,5R)-5-hydroxylysine
PsiMod Definition
A protein modification that effectively converts an L-lysine residue to 5-hydroxy-L-lysine.
Cross References
RefSeq
NP_775736.2
OpenTargets
ENSG00000050767
HPA
ENSG00000050767-COL23A1
GeneCards
Q86Y22
Ensembl
ENST00000390654
,
ENSP00000375069
,
ENSG00000050767
PRO
Q86Y22
Pharos - Targets
Q86Y22
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