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5Hyl-COL14A1 [endoplasmic reticulum lumen]
Stable Identifier
R-HSA-2173048
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum lumen
Synonyms
5-hydroxylysyl-collagen alpha-1(XIV) chain, Collagen alpha-1(XIV) chain, COL14A1, COEA1_HUMAN
Locations in the PathwayBrowser
Expand all
Extracellular matrix organization (Homo sapiens)
Collagen formation (Homo sapiens)
Collagen biosynthesis and modifying enzymes (Homo sapiens)
COLGALT1,COLGALT2 bind Lysyl hydroxylated collagen propeptides (Homo sapiens)
COLGALT1,COLGALT2:Lysyl hydroxylated collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
Lysyl hydroxylated collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
5-Hyl collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
5Hyl-COL14A1 [endoplasmic reticulum lumen] (Homo sapiens)
Lysyl hydroxylated collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
5-Hyl collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
5Hyl-COL14A1 [endoplasmic reticulum lumen] (Homo sapiens)
Collagen chain trimerization (Homo sapiens)
Association of procollagen type XIV (Homo sapiens)
Alpha-1(XIV) chains [endoplasmic reticulum lumen] (Homo sapiens)
5Hyl-COL14A1 [endoplasmic reticulum lumen] (Homo sapiens)
C-linked procollagen type XIV trimer [endoplasmic reticulum lumen] (Homo sapiens)
Alpha-1(XIV) chains [endoplasmic reticulum lumen] (Homo sapiens)
5Hyl-COL14A1 [endoplasmic reticulum lumen] (Homo sapiens)
Galactosylation of collagen propeptide hydroxylysines by PLOD3 (Homo sapiens)
PLOD3:Fe2+ dimer:Lysyl hydroxylated collagen propeptides [endoplasmic reticulum membrane] (Homo sapiens)
Lysyl hydroxylated collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
5-Hyl collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
5Hyl-COL14A1 [endoplasmic reticulum lumen] (Homo sapiens)
Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2 (Homo sapiens)
COLGALT1,COLGALT2:Lysyl hydroxylated collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
Lysyl hydroxylated collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
5-Hyl collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
5Hyl-COL14A1 [endoplasmic reticulum lumen] (Homo sapiens)
Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases (Homo sapiens)
Lysyl hydroxylases:Lysyl hydroxylated collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
Lysyl hydroxylated collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
5-Hyl collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
5Hyl-COL14A1 [endoplasmic reticulum lumen] (Homo sapiens)
Lysyl hydroxylated collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
5-Hyl collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
5Hyl-COL14A1 [endoplasmic reticulum lumen] (Homo sapiens)
PLOD3 binds Lysyl hydroxylated collagen propeptides (Homo sapiens)
Lysyl hydroxylated collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
5-Hyl collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
5Hyl-COL14A1 [endoplasmic reticulum lumen] (Homo sapiens)
PLOD3:Fe2+ dimer:Lysyl hydroxylated collagen propeptides [endoplasmic reticulum membrane] (Homo sapiens)
Lysyl hydroxylated collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
5-Hyl collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
5Hyl-COL14A1 [endoplasmic reticulum lumen] (Homo sapiens)
Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines (Homo sapiens)
Lysyl hydroxylases:Lysyl hydroxylated collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
Lysyl hydroxylated collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
5-Hyl collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
5Hyl-COL14A1 [endoplasmic reticulum lumen] (Homo sapiens)
Procollagen triple helix formation (Homo sapiens)
Collagen and procollagen triple helices:Serpin H1 [endoplasmic reticulum lumen] (Homo sapiens)
Collagen and procollagen triple helices [endoplasmic reticulum lumen] (Homo sapiens)
Non-fibrillar collagens [endoplasmic reticulum lumen] (Homo sapiens)
Collagen type XIV [endoplasmic reticulum lumen] (Homo sapiens)
Alpha-1(XIV) chains [endoplasmic reticulum lumen] (Homo sapiens)
5Hyl-COL14A1 [endoplasmic reticulum lumen] (Homo sapiens)
Procollagen C-linked trimers [endoplasmic reticulum lumen] (Homo sapiens)
C-linked procollagen type XIV trimer [endoplasmic reticulum lumen] (Homo sapiens)
Alpha-1(XIV) chains [endoplasmic reticulum lumen] (Homo sapiens)
5Hyl-COL14A1 [endoplasmic reticulum lumen] (Homo sapiens)
Secretion of collagens (Homo sapiens)
Collagens and tropocollagens:Serpin H1 [endoplasmic reticulum lumen] (Homo sapiens)
Collagens and tropocollagens [endoplasmic reticulum lumen] (Homo sapiens)
Non-fibrillar collagens [endoplasmic reticulum lumen] (Homo sapiens)
Collagen type XIV [endoplasmic reticulum lumen] (Homo sapiens)
Alpha-1(XIV) chains [endoplasmic reticulum lumen] (Homo sapiens)
5Hyl-COL14A1 [endoplasmic reticulum lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q05707 COL14A1
Gene Names
COL14A1, UND
Chain
signal peptide:1-28, chain:29-1796
Reference Genes
BioGPS Gene:7373 COL14A1
COSMIC (genes):COL14A1 COL14A1
CTD Gene:7373 COL14A1
dbSNP Gene:7373 COL14A1
ENSEMBL:ENSG00000187955 COL14A1
ENSEMBL_homo_sapiens_GENE:ENSG00000187955.13 COL14A1
HGNC:2191 COL14A1
KEGG Gene (Homo sapiens):7373 COL14A1
Monarch:7373 COL14A1
NCBI Gene:7373 COL14A1
OMIM:120324 COL14A1
UCSC:Q05707 COL14A1
Reference Transcript
RefSeq:XM_017013809.1 COL14A1
RefSeq:NM_021110.3 COL14A1
RefSeq:XM_006716651.3 COL14A1
RefSeq:XM_005251059.3 COL14A1
Other Identifiers
11749658_a_at
11757921_s_at
11758810_at
17072162
212865_PM_s_at
212865_s_at
216865_PM_at
216865_at
216866_PM_s_at
216866_s_at
228750_PM_at
228750_at
3113360
3113364
3113365
3113366
3113367
3113368
3113370
3113372
3113373
3113374
3113375
3113376
3113377
3113378
3113380
3113382
3113383
3113387
3113388
3113389
3113390
3113392
3113394
3113395
3113397
3113398
3113399
3113401
3113402
3113404
3113407
3113409
3113410
3113411
3113412
3113414
3113416
3113417
3113418
3113419
3113420
3113421
3113422
3113425
3113426
3113429
3113430
3113433
3113438
3113440
3113441
3113442
3113443
3113444
3113445
3113446
3113448
3113449
34388_at
34389_at
44025_at
7373
80069_at
80492_at
8148070
A_23_P216361
A_24_P254789
A_24_P643776
A_32_P80850
GE544996
GE60293
GE842477
GO:0003012
GO:0003229
GO:0003723
GO:0005198
GO:0005201
GO:0005515
GO:0005518
GO:0005576
GO:0005581
GO:0005596
GO:0005614
GO:0005615
GO:0005783
GO:0005788
GO:0007155
GO:0030020
GO:0030154
GO:0030198
GO:0030199
GO:0030312
GO:0030674
GO:0031012
GO:0043226
GO:0048856
GO:0048873
GO:0060090
GO:0061050
GO:0062023
GO:0098609
HMNXSV003047748
HMNXSV003055123
Hs.28625.0.A1_3p_at
Hs.36131.0.S1_3p_a_at
Hs.36131.2.S1_3p_a_at
ILMN_1786598
M64108_at
PH_hs_0019132
TC08000700.hg
Y11709_at
Y11710_rna1_at
Participates
as a member of
Alpha-1(XIV) chains [endoplasmic reticulum lumen] (Homo sapiens)
as a candidate of
5-Hyl collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
Other forms of this molecule
GlcGalHyl-COL14A1 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-GlcGalHyl-COL14A1 [endoplasmic reticulum lumen]
3x4Hyp-GalHyl-COL14A1 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-GalHyl-COL14A1 [endoplasmic reticulum lumen]
3x4Hyp-GlcGalHyl-COL14A1 [endoplasmic reticulum lumen]
GalHyl-COL14A1 [endoplasmic reticulum lumen]
COL14A1 [endoplasmic reticulum lumen]
3x4Hyp-COL14A1 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-COL14A1 [endoplasmic reticulum lumen]
3x4Hyp-5Hyl-COL14A1 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-5Hyl-COL14A1 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-GlcGalHyl-COL14A1(29-?) [extracellular region]
3x4Hyp-COL14A1(?-1796) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL14A1(?-1796) [extracellular region]
COL14A1(?-1796) [extracellular region]
5Hyl-COL14A1(29-?) [extracellular region]
GlcGalHyl-COL14A1(?-1796) [extracellular region]
GlcGalHyl-COL14A1(29-?) [extracellular region]
3x4Hyp-5Hyl-COL14A1(29-?) [extracellular region]
3x4Hyp-GalHyl-COL14A1(29-?) [extracellular region]
GalHyl-COL14A1(29-?) [extracellular region]
3x4Hyp-3Hyp-COL14A1(29-?) [extracellular region]
COL14A1(29-?) [extracellular region]
3x4Hyp-COL14A1(29-?) [extracellular region]
3x4Hyp-GalHyl-COL14A1(?-1796) [extracellular region]
3x4Hyp-3Hyp-COL14A1(?-1796) [extracellular region]
GalHyl-COL14A1(?-1796) [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL14A1(29-?) [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL14A1(?-1796) [extracellular region]
3x4Hyp-GlcGalHyl-COL14A1(?-1796) [extracellular region]
3x4Hyp-GlcGalHyl-COL14A1(29-?) [extracellular region]
5Hyl-COL14A1(?-1796) [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL14A1(?-1796) [extracellular region]
3x4Hyp-5Hyl-COL14A1(?-1796) [extracellular region]
3x4Hyp-GalHyl-COL14A1 [extracellular region]
3x4Hyp-COL14A1 [extracellular region]
3x4Hyp-GlcGalHyl-COL14A1 [extracellular region]
3x4Hyp-3Hyp-COL14A1 [extracellular region]
GalHyl-COL14A1 [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL14A1 [extracellular region]
3x4Hyp-5Hyl-COL14A1 [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL14A1 [extracellular region]
5Hyl-COL14A1 [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL14A1 [extracellular region]
COL14A1 [extracellular region]
GlcGalHyl-COL14A1 [extracellular region]
Inferred To
COL14A1 [endoplasmic reticulum lumen]
(Bos taurus)
COL14A1 [endoplasmic reticulum lumen]
(Canis familiaris)
COL14A1 [endoplasmic reticulum lumen]
(Sus scrofa)
slc35c2 [endoplasmic reticulum lumen]
(Danio rerio)
5Hyl-COL14A1 [endoplasmic reticulum lumen]
(Caenorhabditis elegans)
5Hyl-COL14A1 [endoplasmic reticulum lumen]
(Dictyostelium discoideum)
5Hyl-COL14A1 [endoplasmic reticulum lumen]
(Gallus gallus)
Col14a1 [endoplasmic reticulum lumen]
(Mus musculus)
Col14a1 [endoplasmic reticulum lumen]
(Rattus norvegicus)
Modified Residues
Name
(2S,5R)-5-hydroxylysine at unknown position
PsiMod Name
(2S,5R)-5-hydroxylysine
PsiMod Definition
A protein modification that effectively converts an L-lysine residue to 5-hydroxy-L-lysine.
Cross References
RefSeq
XP_005251116.1
,
XP_016869298.1
,
NP_066933.1
,
XP_006716714.1
OpenTargets
ENSG00000187955
HPA
ENSG00000187955-COL14A1
GeneCards
Q05707
Ensembl
ENST00000309791
,
ENST00000297848
,
ENSP00000297848
,
ENSG00000187955
,
ENSP00000311809
PRO
Q05707
Pharos - Targets
Q05707
Orphanet
21446
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P32119 PRDX2
2
p-T89-PRDX2 [cytosol]
(R-HSA-8868574)
PRDX2 [cytosol]
(R-HSA-3341292)
0.508
2
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