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3x4Hyp-COL26A1 [endoplasmic reticulum lumen]
Stable Identifier
R-HSA-2172929
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum lumen
Synonyms
3x4Hyp-EMID2, 4-hydroxyprolyl collagen alpha-1(XXVI) chain, EMID2, EMID2_HUMAN
Locations in the PathwayBrowser
Expand all
Extracellular matrix organization (Homo sapiens)
Collagen formation (Homo sapiens)
Collagen biosynthesis and modifying enzymes (Homo sapiens)
Collagen chain trimerization (Homo sapiens)
Association of procollagen type XXVI (Homo sapiens)
Alpha-1(XXVI) chains [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-COL26A1 [endoplasmic reticulum lumen] (Homo sapiens)
C-linked procollagen type XXVI trimer [endoplasmic reticulum lumen] (Homo sapiens)
Alpha-1(XXVI) chains [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-COL26A1 [endoplasmic reticulum lumen] (Homo sapiens)
Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen (Homo sapiens)
Prolyl 3-hydroxylases:Fe2+:4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-COL26A1 [endoplasmic reticulum lumen] (Homo sapiens)
P3HB binds 4-Hyp-collagen propeptides (Homo sapiens)
4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-COL26A1 [endoplasmic reticulum lumen] (Homo sapiens)
Prolyl 3-hydroxylases:Fe2+:4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-COL26A1 [endoplasmic reticulum lumen] (Homo sapiens)
P4HB:4-Hyp collagen propeptides dissociates (Homo sapiens)
4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-COL26A1 [endoplasmic reticulum lumen] (Homo sapiens)
4-Hyp collagen propeptides:P4HB [endoplasmic reticulum lumen] (Homo sapiens)
4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-COL26A1 [endoplasmic reticulum lumen] (Homo sapiens)
Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines (Homo sapiens)
Lysyl hydroxylases:Lysyl hydroxylase procollagen substrates [endoplasmic reticulum membrane] (Homo sapiens)
Lysyl hydroxylase procollagen substrates [endoplasmic reticulum lumen] (Homo sapiens)
4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-COL26A1 [endoplasmic reticulum lumen] (Homo sapiens)
Procollagen triple helix formation (Homo sapiens)
Collagen and procollagen triple helices:Serpin H1 [endoplasmic reticulum lumen] (Homo sapiens)
Collagen and procollagen triple helices [endoplasmic reticulum lumen] (Homo sapiens)
Non-fibrillar collagens [endoplasmic reticulum lumen] (Homo sapiens)
Tropocollagen type XXVI [endoplasmic reticulum lumen] (Homo sapiens)
Alpha-1(XXVI) chains [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-COL26A1 [endoplasmic reticulum lumen] (Homo sapiens)
Procollagen C-linked trimers [endoplasmic reticulum lumen] (Homo sapiens)
C-linked procollagen type XXVI trimer [endoplasmic reticulum lumen] (Homo sapiens)
Alpha-1(XXVI) chains [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-COL26A1 [endoplasmic reticulum lumen] (Homo sapiens)
Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines (Homo sapiens)
4-Hyp collagen propeptides:P4HB [endoplasmic reticulum lumen] (Homo sapiens)
4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-COL26A1 [endoplasmic reticulum lumen] (Homo sapiens)
Secretion of collagens (Homo sapiens)
Collagens and tropocollagens:Serpin H1 [endoplasmic reticulum lumen] (Homo sapiens)
Collagens and tropocollagens [endoplasmic reticulum lumen] (Homo sapiens)
Non-fibrillar collagens [endoplasmic reticulum lumen] (Homo sapiens)
Tropocollagen type XXVI [endoplasmic reticulum lumen] (Homo sapiens)
Alpha-1(XXVI) chains [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-COL26A1 [endoplasmic reticulum lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q96A83 COL26A1
Gene Names
COL26A1, EMID2, EMU2
Chain
signal peptide:1-20, chain:21-441
Reference Genes
BioGPS Gene:136227 COL26A1
COSMIC (genes):COL26A1 COL26A1
CTD Gene:136227 COL26A1
dbSNP Gene:136227 COL26A1
ENSEMBL:ENSG00000160963 COL26A1
ENSEMBL_homo_sapiens_GENE:ENSG00000160963.14 COL26A1
HGNC:18038 COL26A1
KEGG Gene (Homo sapiens):136227 COL26A1
Monarch:136227 COL26A1
NCBI Gene:136227 COL26A1
OMIM:608927 COL26A1
UCSC:Q96A83 COL26A1
Reference Transcript
RefSeq:NM_133457.4 COL26A1
RefSeq:NM_001278563.2 COL26A1
Other Identifiers
11725179_at
136227
17049717
229080_PM_at
229080_at
233894_PM_x_at
233894_x_at
3016263
3016264
3016273
3016277
3016286
3016287
3016288
3016290
3016291
3016292
3016293
3016295
3016296
3016298
3016299
3016300
3016301
3016302
3016303
3016304
3016305
3016306
50115_at
52360_at
56557_at
8135099
A_23_P134627
GE812150
GE876293
GO:0005515
GO:0005576
GO:0005581
GO:0005783
GO:0005788
GO:0005794
GO:0005886
GO:0007155
GO:0010811
GO:0030312
GO:0031012
GO:0043226
GO:0062023
HMNXSV003045497
Hs.247832.0.S1_3p_at
Hs.247832.0.S1_3p_x_at
Hs.27115.0.A1_3p_at
TC07000649.hg
Participates
as a member of
Alpha-1(XXVI) chains [endoplasmic reticulum lumen] (Homo sapiens)
as a candidate of
4-Hyp collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
Other forms of this molecule
3x4Hyp-5Hyl-COL26A1 [extracellular region]
3x4Hyp-GalHyl-COL26A1 [extracellular region]
3x4Hyp-3Hyp-COL26A1 [extracellular region]
5Hyl-COL26A1 [extracellular region]
3x4Hyp-GlcGalHyl-COL26A1 [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL26A1 [extracellular region]
GlcGalHyl-COL26A1 [extracellular region]
3x4Hyp-COL26A1 [extracellular region]
COL26A1 [extracellular region]
GalHyl-COL26A1 [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL26A1 [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL26A1 [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL26A1 [endoplasmic reticulum lumen]
3x4Hyp-GlcGalHyl-COL26A1 [endoplasmic reticulum lumen]
GlcGalHyl-COL26A1 [endoplasmic reticulum lumen]
COL26A1 [plasma membrane]
5Hyl-COL26A1 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-5Hyl-COL26A1 [endoplasmic reticulum lumen]
3x4Hyp-5Hyl-COL26A1 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-COL26A1 [endoplasmic reticulum lumen]
COL26A1 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-GalHyl-COL26A1 [endoplasmic reticulum lumen]
3x4Hyp-GalHyl-COL26A1 [endoplasmic reticulum lumen]
GalHyl-COL26A1 [endoplasmic reticulum lumen]
Inferred To
Col26a1 [endoplasmic reticulum lumen]
(Mus musculus)
Col26a1 [endoplasmic reticulum lumen]
(Rattus norvegicus)
3x4Hyp-COL26A1 [endoplasmic reticulum lumen]
(Gallus gallus)
COL26A1 [endoplasmic reticulum lumen]
(Bos taurus)
COL26A1 [endoplasmic reticulum lumen]
(Canis familiaris)
Modified Residues
Name
(2S,4R)-4-hydroxyproline at unknown position
PsiMod Name
(2S,4R)-4-hydroxyproline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline
Name
(2S,4R)-4-hydroxyproline at unknown position
PsiMod Name
(2S,4R)-4-hydroxyproline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline
Name
(2S,4R)-4-hydroxyproline at unknown position
PsiMod Name
(2S,4R)-4-hydroxyproline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline
Cross References
RefSeq
NP_001265492.1
,
NP_597714.2
OpenTargets
ENSG00000160963
GeneCards
Q96A83
HPA
ENSG00000160963-COL26A1
Ensembl
ENSP00000482102
,
ENSG00000160963
,
ENST00000313669
,
ENST00000613501
,
ENSP00000318234
PRO
Q96A83
Pharos - Targets
Q96A83
PDB
4AU2
,
4AU3
,
4BJ3
,
7BEE
,
7BFI
,
7BDU
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