4-hydroxybenzoate polyprenyltransferase, mitochondrial (COQ2) catalyses the combination of 4-hydroxybenzoic acid, aka para-hydroxybenzoic acid (PHB) with the polyisoprenoid tail all-trans-decaprenyl diphosphate (all-E-10PrP2) to form 3-decaprenyl-4-hydroxybenzoic acid (DHB) (Forsgren et a l. 2004, Tekle et al. 2008). This reaction is irreversible and occurs in the mitochondria.
Dallner, G, Turunen, M, Swiezewska, E, Tekle, M, Chojnacki, T
Dallner, G, Climent, I, Grünler, J, Attersand, A, Swiezewska, E, Forsgren, M, Lake, S
4-hydroxybenzoate decaprenyltransferase activity of COQ2 [mitochondrial inner membrane]
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