Interaction of integrin alphaXbeta2 with fibrin

Stable Identifier
R-HSA-216082
Type
Reaction
Species
Homo sapiens
Compartment
extracellular region, plasma membrane
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Interaction of integrin alphaXbeta2 with fibrin
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Integrin alphaXbeta2 serves as a cell surface receptor for fibrinogen and plays an important role in leuckocyte functions including phagocytosis and migration.

Literature References
PubMed ID Title Journal Year
10543983 Characteristics of fibrinogen binding to the domain of CD11c, an alpha subunit of p150,95

Nham, SU

Biochem Biophys Res Commun 1999
17339034 Critical residues of alphaX I-domain recognizing fibrinogen central domain

Choi, J, Nham, SU, Lee, JH

Biochem Biophys Res Commun 2007
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Orthologous Events
Interaction of integrin alphaXbeta2 with fibrin (Mus musculus)
Interaction of integrin alphaXbeta2 with fibrin (Rattus norvegicus)
Authored
Geiger, B  (2008-05-07)
Horwitz, AR  (2008-05-07)
Reviewed
Humphries, MJ  (2008-05-07)
Yamada, KM  (2008-05-07)
Hynes, R  (2008-05-07)
Created
Garapati, P V  (2008-03-11)
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