Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
FBN3(32-2689) [extracellular region]
Stable Identifier
R-HSA-2159815
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
Fibrillin-3 peptide, FBN3, FBN3_HUMAN
Locations in the PathwayBrowser
Expand all
Extracellular matrix organization (Homo sapiens)
Degradation of the extracellular matrix (Homo sapiens)
Fibrillin 1, 2,(3) degradation by MMP2, 9, 12 and 13 (Homo sapiens)
Fibrillin 1,2,(3) [extracellular region] (Homo sapiens)
Fibrillin-3 [extracellular region] (Homo sapiens)
FBN3(32-2689) [extracellular region] (Homo sapiens)
Elastic fibre formation (Homo sapiens)
Elastin cross-linking by lysyl oxidase (Homo sapiens)
Elastic fibre [extracellular region] (Homo sapiens)
Fibrilins:MFAP2,MFAP5 [extracellular region] (Homo sapiens)
Fibrillin 1,2,(3) [extracellular region] (Homo sapiens)
Fibrillin-3 [extracellular region] (Homo sapiens)
FBN3(32-2689) [extracellular region] (Homo sapiens)
Fibrillins:MFAP2,MFAP5:Tropoelastin aggregate [extracellular region] (Homo sapiens)
Fibrilins:MFAP2,MFAP5 [extracellular region] (Homo sapiens)
Fibrillin 1,2,(3) [extracellular region] (Homo sapiens)
Fibrillin-3 [extracellular region] (Homo sapiens)
FBN3(32-2689) [extracellular region] (Homo sapiens)
Fibrillin C-terminal processing (Homo sapiens)
Fibrillin peptides [extracellular region] (Homo sapiens)
FBN3(32-2689) [extracellular region] (Homo sapiens)
Fibrillin microfibril assembly (Homo sapiens)
Fibrillin 1,2,(3) [extracellular region] (Homo sapiens)
Fibrillin-3 [extracellular region] (Homo sapiens)
FBN3(32-2689) [extracellular region] (Homo sapiens)
Fibrillin peptides [extracellular region] (Homo sapiens)
FBN3(32-2689) [extracellular region] (Homo sapiens)
MFAP2, MFAP5 bind microfibrils (Homo sapiens)
Fibrilins:MFAP2,MFAP5 [extracellular region] (Homo sapiens)
Fibrillin 1,2,(3) [extracellular region] (Homo sapiens)
Fibrillin-3 [extracellular region] (Homo sapiens)
FBN3(32-2689) [extracellular region] (Homo sapiens)
Fibrillin 1,2,(3) [extracellular region] (Homo sapiens)
Fibrillin-3 [extracellular region] (Homo sapiens)
FBN3(32-2689) [extracellular region] (Homo sapiens)
Molecules associated with elastic fibres (Homo sapiens)
Elastic fibres bind associated proteins (Homo sapiens)
Elastic fibre with associated proteins [extracellular region] (Homo sapiens)
Elastic fibre:Fibulins:Emilins [extracellular region] (Homo sapiens)
Elastic fibre:Fibulins [extracellular region] (Homo sapiens)
Elastic fibre [extracellular region] (Homo sapiens)
Fibrilins:MFAP2,MFAP5 [extracellular region] (Homo sapiens)
Fibrillin 1,2,(3) [extracellular region] (Homo sapiens)
Fibrillin-3 [extracellular region] (Homo sapiens)
FBN3(32-2689) [extracellular region] (Homo sapiens)
Elastic fibre:Fibulins:Emilins [extracellular region] (Homo sapiens)
Elastic fibre:Fibulins [extracellular region] (Homo sapiens)
Elastic fibre [extracellular region] (Homo sapiens)
Fibrilins:MFAP2,MFAP5 [extracellular region] (Homo sapiens)
Fibrillin 1,2,(3) [extracellular region] (Homo sapiens)
Fibrillin-3 [extracellular region] (Homo sapiens)
FBN3(32-2689) [extracellular region] (Homo sapiens)
Emilin is found in elastic fibres (Homo sapiens)
Elastic fibre:Fibulins [extracellular region] (Homo sapiens)
Elastic fibre [extracellular region] (Homo sapiens)
Fibrilins:MFAP2,MFAP5 [extracellular region] (Homo sapiens)
Fibrillin 1,2,(3) [extracellular region] (Homo sapiens)
Fibrillin-3 [extracellular region] (Homo sapiens)
FBN3(32-2689) [extracellular region] (Homo sapiens)
Elastic fibre:Fibulins:Emilins [extracellular region] (Homo sapiens)
Elastic fibre:Fibulins [extracellular region] (Homo sapiens)
Elastic fibre [extracellular region] (Homo sapiens)
Fibrilins:MFAP2,MFAP5 [extracellular region] (Homo sapiens)
Fibrillin 1,2,(3) [extracellular region] (Homo sapiens)
Fibrillin-3 [extracellular region] (Homo sapiens)
FBN3(32-2689) [extracellular region] (Homo sapiens)
Fibrillins bind BMPs (Homo sapiens)
Fibrillin 1,2,(3) [extracellular region] (Homo sapiens)
Fibrillin-3 [extracellular region] (Homo sapiens)
FBN3(32-2689) [extracellular region] (Homo sapiens)
Fibrillins:BMP2,4,7,10,GF5 [extracellular region] (Homo sapiens)
Fibrillin 1,2,(3) [extracellular region] (Homo sapiens)
Fibrillin-3 [extracellular region] (Homo sapiens)
FBN3(32-2689) [extracellular region] (Homo sapiens)
Fibulin binds elastic fibres (Homo sapiens)
Elastic fibre [extracellular region] (Homo sapiens)
Fibrilins:MFAP2,MFAP5 [extracellular region] (Homo sapiens)
Fibrillin 1,2,(3) [extracellular region] (Homo sapiens)
Fibrillin-3 [extracellular region] (Homo sapiens)
FBN3(32-2689) [extracellular region] (Homo sapiens)
Elastic fibre:Fibulins [extracellular region] (Homo sapiens)
Elastic fibre [extracellular region] (Homo sapiens)
Fibrilins:MFAP2,MFAP5 [extracellular region] (Homo sapiens)
Fibrillin 1,2,(3) [extracellular region] (Homo sapiens)
Fibrillin-3 [extracellular region] (Homo sapiens)
FBN3(32-2689) [extracellular region] (Homo sapiens)
Tropoelastin associates with microfibrils (Homo sapiens)
Fibrilins:MFAP2,MFAP5 [extracellular region] (Homo sapiens)
Fibrillin 1,2,(3) [extracellular region] (Homo sapiens)
Fibrillin-3 [extracellular region] (Homo sapiens)
FBN3(32-2689) [extracellular region] (Homo sapiens)
Fibrillins:MFAP2,MFAP5:Tropoelastin aggregate [extracellular region] (Homo sapiens)
Fibrilins:MFAP2,MFAP5 [extracellular region] (Homo sapiens)
Fibrillin 1,2,(3) [extracellular region] (Homo sapiens)
Fibrillin-3 [extracellular region] (Homo sapiens)
FBN3(32-2689) [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q75N90 FBN3
Gene Names
FBN3, KIAA1776
Chain
signal peptide:1-31, propeptide:32-48, chain:49-2689, chain:2690-2809
Reference Genes
BioGPS Gene:84467 FBN3
COSMIC (genes):FBN3 FBN3
CTD Gene:84467 FBN3
dbSNP Gene:84467 FBN3
ENSEMBL:ENSG00000142449 FBN3
ENSEMBL_homo_sapiens_GENE:ENSG00000142449.13 FBN3
HGNC:18794 FBN3
KEGG Gene (Homo sapiens):84467 FBN3
Monarch:84467 FBN3
NCBI Gene:84467 FBN3
OMIM:608529 FBN3
UCSC:Q75N90 FBN3
Reference Transcript
RefSeq:XM_017027372.1 FBN3
RefSeq:NM_032447.4 FBN3
RefSeq:NM_001321431.1 FBN3
Other Identifiers
11732438_a_at
16868063
240117_PM_at
240117_at
3848746
3848747
3848748
3848751
3848752
3848754
3848755
3848757
3848758
3848759
3848761
3848762
3848763
3848764
3848766
3848767
3848769
3848771
3848773
3848774
3848777
3848778
3848780
3848781
3848783
3848784
3848785
3848786
3848787
3848788
3848789
3848790
3848792
3848793
3848794
3848796
3848797
3848798
3848799
3848802
3848804
3848805
3848806
3848809
3848810
3848811
3848812
3848813
3848814
3848815
3848818
3848820
3848821
3848822
3848823
3848824
3848825
3848826
3848827
3848828
3848829
3848830
3848831
3848832
3848834
3848835
3848836
3848837
3848838
3848839
3848841
3848842
3848843
3848844
56445_at
8033487
84467
A_23_P101893
A_33_P3300430
GE83421
GO:0001527
GO:0005198
GO:0005201
GO:0005509
GO:0005576
GO:0009653
GO:0030312
GO:0031012
GO:0048856
HMNXSV003002311
Hs.116265.0.A1_3p_at
ILMN_1719755
PH_hs_0024137
TC19001126.hg
Participates
as a candidate of
Fibrillin peptides [extracellular region] (Homo sapiens)
as a repeated unit of
Fibrillin-3 [extracellular region] (Homo sapiens)
Other forms of this molecule
FBN3(2690-2809) [extracellular region]
FBN3 [extracellular region]
FBN3(32-?) [extracellular region]
FBN3(1-2689) [extracellular region]
Inferred To
Homologues of FBN3(32-2689) [extracellular region]
(Dictyostelium discoideum)
FBN3 [extracellular region]
(Canis familiaris)
FBN3 [extracellular region]
(Sus scrofa)
fbn2b [extracellular region]
(Danio rerio)
FBN3(32-2689) [extracellular region]
(Bos taurus)
FBN3(32-2689) [extracellular region]
(Dictyostelium discoideum)
Cross References
RefSeq
NP_115823.3
,
NP_001308360.1
,
XP_016882861.1
OpenTargets
ENSG00000142449
HPA
ENSG00000142449-FBN3
GeneCards
Q75N90
Ensembl
ENST00000600128
,
ENST00000270509
,
ENST00000601739
,
ENSG00000142449
,
ENSP00000470498
,
ENSP00000472324
,
ENSP00000270509
PRO
Q75N90
Pharos - Targets
Q75N90
HMDB Protein
HMDBP07681
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text