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PTGR1 [cytosol]
Stable Identifier
R-HSA-2142671
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Prostaglandin reductase 1, PTGR1_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Biosynthesis of specialized proresolving mediators (SPMs) (Homo sapiens)
Biosynthesis of Lipoxins (LX) (Homo sapiens)
15k-LXA4 is reduced to dhk-LXA4 by PTGR1 (Homo sapiens)
PTGR1 [cytosol] (Homo sapiens)
Fatty acid metabolism (Homo sapiens)
Arachidonate metabolism (Homo sapiens)
Synthesis of Leukotrienes (LT) and Eoxins (EX) (Homo sapiens)
LTB4 is oxidised to 12-oxoLTB4 by PTGR1 (Homo sapiens)
PTGR1 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q14914 PTGR1
Gene Names
PTGR1, LTB4DH
Chain
chain:1-329
Reference Genes
BioGPS Gene:22949 PTGR1
COSMIC (genes):PTGR1 PTGR1
CTD Gene:22949 PTGR1
dbSNP Gene:22949 PTGR1
ENSEMBL:ENSG00000106853 PTGR1
ENSEMBL_homo_sapiens_GENE:ENSG00000106853.20 PTGR1
HGNC:18429 PTGR1
KEGG Gene (Homo sapiens):22949 PTGR1
Monarch:22949 PTGR1
NCBI Gene:22949 PTGR1
OMIM:601274 PTGR1
UCSC:Q14914 PTGR1
Reference Transcript
RefSeq:NM_012212.3 PTGR1
RefSeq:NM_001146109.1 PTGR1
RefSeq:NM_001146108.1 PTGR1
Other Identifiers
11736655_a_at
17097211
228824_PM_s_at
228824_s_at
22949
231897_PM_at
231897_at
2356786
3220674
3220675
3220676
3220677
3220683
3220685
3220686
3220687
3220688
3220689
3220698
3220699
3220702
3220705
3220706
8163328
89805_at
A_23_P157809
D49387_at
GE61502
GO:0003824
GO:0005515
GO:0005576
GO:0005615
GO:0005737
GO:0006629
GO:0006631
GO:0006691
GO:0006693
GO:0016491
GO:0016628
GO:0032440
GO:0035798
GO:0036102
GO:0036132
GO:0036185
GO:0043226
GO:0047522
GO:0070062
GO:0097257
GO:2001302
HMNXSV003008815
Hs.114670.0.A1_3p_at
Hs.114670.0.A1_3p_s_at
Hs.297143.0.S1_3p_at
ILMN_1704531
ILMN_2225537
PH_hs_0023561
TC09001484.hg
Cross References
RefSeq
NP_001139580.1
,
NP_001139581.1
,
NP_036344.2
OpenTargets
ENSG00000106853
HPA
ENSG00000106853-PTGR1
GeneCards
Q14914
Ensembl
ENSP00000440281
,
ENSG00000106853
,
ENST00000407693
,
ENST00000538962
,
ENSP00000385763
,
ENST00000309195
,
ENSP00000311572
PRO
Q14914
Pharos - Targets
Q14914
HMDB Protein
HMDBP01616
PDB
2Y05
,
1ZSV
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q8WXH2 JPH3
0.556
3
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