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3Hyp-4Hyp-COL6A5 [extracellular region]
Stable Identifier
R-HSA-2127518
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
3,4-hydroxyprolyl collagen alpha-5(VI) chain, CO6A5_HUMAN, COL29A1
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Nervous system development (Homo sapiens)
Axon guidance (Homo sapiens)
NCAM signaling for neurite out-growth (Homo sapiens)
NCAM1 interactions (Homo sapiens)
Interaction of NCAM1 with collagens (Homo sapiens)
Collagens [extracellular region] (Homo sapiens)
Tropocollagen type VI [extracellular region] (Homo sapiens)
Collagen alpha 3-6(VI) [extracellular region] (Homo sapiens)
Collagen alpha-5(VI) chains [extracellular region] (Homo sapiens)
3Hyp-4Hyp-COL6A5 [extracellular region] (Homo sapiens)
NCAM-1:Collagen complex [plasma membrane] (Homo sapiens)
Collagens [extracellular region] (Homo sapiens)
Tropocollagen type VI [extracellular region] (Homo sapiens)
Collagen alpha 3-6(VI) [extracellular region] (Homo sapiens)
Collagen alpha-5(VI) chains [extracellular region] (Homo sapiens)
3Hyp-4Hyp-COL6A5 [extracellular region] (Homo sapiens)
Extracellular matrix organization (Homo sapiens)
Collagen formation (Homo sapiens)
Assembly of collagen fibrils and other multimeric structures (Homo sapiens)
Formation of collagen networks (Homo sapiens)
Collagen networks [extracellular region] (Homo sapiens)
Collagen type VI network [extracellular region] (Homo sapiens)
Collagen type VI tetramer [extracellular region] (Homo sapiens)
Tropocollagen type VI dimer [extracellular region] (Homo sapiens)
Tropocollagen type VI [extracellular region] (Homo sapiens)
Collagen alpha 3-6(VI) [extracellular region] (Homo sapiens)
Collagen alpha-5(VI) chains [extracellular region] (Homo sapiens)
3Hyp-4Hyp-COL6A5 [extracellular region] (Homo sapiens)
Network forming tropocollagens [extracellular region] (Homo sapiens)
Collagen type VI tetramer [extracellular region] (Homo sapiens)
Tropocollagen type VI dimer [extracellular region] (Homo sapiens)
Tropocollagen type VI [extracellular region] (Homo sapiens)
Collagen alpha 3-6(VI) [extracellular region] (Homo sapiens)
Collagen alpha-5(VI) chains [extracellular region] (Homo sapiens)
3Hyp-4Hyp-COL6A5 [extracellular region] (Homo sapiens)
Collagen biosynthesis and modifying enzymes (Homo sapiens)
Secretion of collagens (Homo sapiens)
Collagens and tropocollagens [extracellular region] (Homo sapiens)
Collagen type VI tetramer [extracellular region] (Homo sapiens)
Tropocollagen type VI dimer [extracellular region] (Homo sapiens)
Tropocollagen type VI [extracellular region] (Homo sapiens)
Collagen alpha 3-6(VI) [extracellular region] (Homo sapiens)
Collagen alpha-5(VI) chains [extracellular region] (Homo sapiens)
3Hyp-4Hyp-COL6A5 [extracellular region] (Homo sapiens)
Degradation of the extracellular matrix (Homo sapiens)
Collagen degradation (Homo sapiens)
Collagen type VI degradation by MMP2,9,11 (Homo sapiens)
Collagen type VI fibril [extracellular region] (Homo sapiens)
Collagen type VI tetramer [extracellular region] (Homo sapiens)
Tropocollagen type VI dimer [extracellular region] (Homo sapiens)
Tropocollagen type VI [extracellular region] (Homo sapiens)
Collagen alpha 3-6(VI) [extracellular region] (Homo sapiens)
Collagen alpha-5(VI) chains [extracellular region] (Homo sapiens)
3Hyp-4Hyp-COL6A5 [extracellular region] (Homo sapiens)
ECM proteoglycans (Homo sapiens)
BGN binds Collagen types I, VI, (IX) (Homo sapiens)
BGN:Collagen types I, VI, (IX) [extracellular region] (Homo sapiens)
Collagen types I, VI, (IX) [extracellular region] (Homo sapiens)
Collagen type VI network [extracellular region] (Homo sapiens)
Collagen type VI tetramer [extracellular region] (Homo sapiens)
Tropocollagen type VI dimer [extracellular region] (Homo sapiens)
Tropocollagen type VI [extracellular region] (Homo sapiens)
Collagen alpha 3-6(VI) [extracellular region] (Homo sapiens)
Collagen alpha-5(VI) chains [extracellular region] (Homo sapiens)
3Hyp-4Hyp-COL6A5 [extracellular region] (Homo sapiens)
Collagen types I, VI, (IX) [extracellular region] (Homo sapiens)
Collagen type VI network [extracellular region] (Homo sapiens)
Collagen type VI tetramer [extracellular region] (Homo sapiens)
Tropocollagen type VI dimer [extracellular region] (Homo sapiens)
Tropocollagen type VI [extracellular region] (Homo sapiens)
Collagen alpha 3-6(VI) [extracellular region] (Homo sapiens)
Collagen alpha-5(VI) chains [extracellular region] (Homo sapiens)
3Hyp-4Hyp-COL6A5 [extracellular region] (Homo sapiens)
DCN binds collagen I, II, III, VI fibrils (Homo sapiens)
Collagen type I, II, III, VI fibrils [extracellular region] (Homo sapiens)
Collagen type VI fibril [extracellular region] (Homo sapiens)
Collagen type VI tetramer [extracellular region] (Homo sapiens)
Tropocollagen type VI dimer [extracellular region] (Homo sapiens)
Tropocollagen type VI [extracellular region] (Homo sapiens)
Collagen alpha 3-6(VI) [extracellular region] (Homo sapiens)
Collagen alpha-5(VI) chains [extracellular region] (Homo sapiens)
3Hyp-4Hyp-COL6A5 [extracellular region] (Homo sapiens)
DCN:Collagen type I, II, III, VI fibrils [extracellular region] (Homo sapiens)
Collagen type I, II, III, VI fibrils [extracellular region] (Homo sapiens)
Collagen type VI fibril [extracellular region] (Homo sapiens)
Collagen type VI tetramer [extracellular region] (Homo sapiens)
Tropocollagen type VI dimer [extracellular region] (Homo sapiens)
Tropocollagen type VI [extracellular region] (Homo sapiens)
Collagen alpha 3-6(VI) [extracellular region] (Homo sapiens)
Collagen alpha-5(VI) chains [extracellular region] (Homo sapiens)
3Hyp-4Hyp-COL6A5 [extracellular region] (Homo sapiens)
VTN binds collagens I, IV and VI (Homo sapiens)
Collagen type I,IV,VI [extracellular region] (Homo sapiens)
Collagen type VI fibril [extracellular region] (Homo sapiens)
Collagen type VI tetramer [extracellular region] (Homo sapiens)
Tropocollagen type VI dimer [extracellular region] (Homo sapiens)
Tropocollagen type VI [extracellular region] (Homo sapiens)
Collagen alpha 3-6(VI) [extracellular region] (Homo sapiens)
Collagen alpha-5(VI) chains [extracellular region] (Homo sapiens)
3Hyp-4Hyp-COL6A5 [extracellular region] (Homo sapiens)
VTN:Collagen type I,IV,VI [extracellular region] (Homo sapiens)
Collagen type I,IV,VI [extracellular region] (Homo sapiens)
Collagen type VI fibril [extracellular region] (Homo sapiens)
Collagen type VI tetramer [extracellular region] (Homo sapiens)
Tropocollagen type VI dimer [extracellular region] (Homo sapiens)
Tropocollagen type VI [extracellular region] (Homo sapiens)
Collagen alpha 3-6(VI) [extracellular region] (Homo sapiens)
Collagen alpha-5(VI) chains [extracellular region] (Homo sapiens)
3Hyp-4Hyp-COL6A5 [extracellular region] (Homo sapiens)
Integrin cell surface interactions (Homo sapiens)
Collagen types III, IV, V, VI, VIII, IX, XVI bind integrins alpha1beta1 and alpha2beta1 (Homo sapiens)
Collagen types III, IV, V, VI, VIII, IX, XVI [extracellular region] (Homo sapiens)
Collagen type VI network [extracellular region] (Homo sapiens)
Collagen type VI tetramer [extracellular region] (Homo sapiens)
Tropocollagen type VI dimer [extracellular region] (Homo sapiens)
Tropocollagen type VI [extracellular region] (Homo sapiens)
Collagen alpha 3-6(VI) [extracellular region] (Homo sapiens)
Collagen alpha-5(VI) chains [extracellular region] (Homo sapiens)
3Hyp-4Hyp-COL6A5 [extracellular region] (Homo sapiens)
Collagen types III, IV, V, VI, VIII, IX, XVI:Integrins alpha1beta 1, alpha2beta1 [plasma membrane] (Homo sapiens)
Collagen types III, IV, V, VI, VIII, IX, XVI [extracellular region] (Homo sapiens)
Collagen type VI network [extracellular region] (Homo sapiens)
Collagen type VI tetramer [extracellular region] (Homo sapiens)
Tropocollagen type VI dimer [extracellular region] (Homo sapiens)
Tropocollagen type VI [extracellular region] (Homo sapiens)
Collagen alpha 3-6(VI) [extracellular region] (Homo sapiens)
Collagen alpha-5(VI) chains [extracellular region] (Homo sapiens)
3Hyp-4Hyp-COL6A5 [extracellular region] (Homo sapiens)
Collagen types VI, IX bind integrin alpha10beta1 (Homo sapiens)
Collagen tupe VI network, Collagen type IX:Integrin alpha10beta1 [plasma membrane] (Homo sapiens)
Collagen type VI network, Collagen type IX [extracellular region] (Homo sapiens)
Collagen type VI network [extracellular region] (Homo sapiens)
Collagen type VI tetramer [extracellular region] (Homo sapiens)
Tropocollagen type VI dimer [extracellular region] (Homo sapiens)
Tropocollagen type VI [extracellular region] (Homo sapiens)
Collagen alpha 3-6(VI) [extracellular region] (Homo sapiens)
Collagen alpha-5(VI) chains [extracellular region] (Homo sapiens)
3Hyp-4Hyp-COL6A5 [extracellular region] (Homo sapiens)
Collagen type VI network, Collagen type IX [extracellular region] (Homo sapiens)
Collagen type VI network [extracellular region] (Homo sapiens)
Collagen type VI tetramer [extracellular region] (Homo sapiens)
Tropocollagen type VI dimer [extracellular region] (Homo sapiens)
Tropocollagen type VI [extracellular region] (Homo sapiens)
Collagen alpha 3-6(VI) [extracellular region] (Homo sapiens)
Collagen alpha-5(VI) chains [extracellular region] (Homo sapiens)
3Hyp-4Hyp-COL6A5 [extracellular region] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by PDGF (Homo sapiens)
PDGF binds to extracellular matrix proteins (Homo sapiens)
Extracellular matrix ligands [extracellular region] (Homo sapiens)
Collagens [extracellular region] (Homo sapiens)
Tropocollagen type VI [extracellular region] (Homo sapiens)
Collagen alpha 3-6(VI) [extracellular region] (Homo sapiens)
Collagen alpha-5(VI) chains [extracellular region] (Homo sapiens)
3Hyp-4Hyp-COL6A5 [extracellular region] (Homo sapiens)
PDGF A and B chains:ECM complex [extracellular region] (Homo sapiens)
Extracellular matrix ligands [extracellular region] (Homo sapiens)
Collagens [extracellular region] (Homo sapiens)
Tropocollagen type VI [extracellular region] (Homo sapiens)
Collagen alpha 3-6(VI) [extracellular region] (Homo sapiens)
Collagen alpha-5(VI) chains [extracellular region] (Homo sapiens)
3Hyp-4Hyp-COL6A5 [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:A8TX70 COL6A5
Gene Names
COL6A5, COL29A1, VWA4
Chain
signal peptide:1-18, chain:19-2615
Reference Genes
BioGPS Gene:256076 COL6A5
COSMIC (genes):COL6A5 COL6A5
CTD Gene:256076 COL6A5
dbSNP Gene:256076 COL6A5
ENSEMBL:ENSG00000172752 COL6A5
ENSEMBL_homo_sapiens_GENE:ENSG00000172752.16 COL6A5
HGNC:26674 COL6A5
KEGG Gene (Homo sapiens):256076 COL6A5
Monarch:256076 COL6A5
NCBI Gene:256076 COL6A5
OMIM:611916 COL6A5
UCSC:A8TX70 COL6A5
Reference Transcript
RefSeq:NM_153264.6 COL6A5
RefSeq:NM_001278298.1 COL6A5
Other Identifiers
11734466_a_at
1553834_3p_at
1553834_PM_at
1553834_at
1553835_PM_a_at
1553835_a_at
16945497
256076
2642113
2642115
2642124
2642127
2642128
2642131
2642133
2642135
2642136
2642139
2642140
2642141
2642142
2642143
2642144
2642145
2642146
2642147
2642148
2642149
2642150
2642151
2642152
2642153
2642154
2642155
2642156
2642157
2642158
2642161
2642164
2642165
2642166
2642167
2642170
2642262
2642263
2642266
2642267
2642268
2642269
2642270
2642271
2642272
2642273
2642274
2642275
2642276
2642278
2642279
8082585
A_14_P108064
A_14_P201019
A_14_P201688
A_23_P404698
GE906554
GO:0005198
GO:0005515
GO:0005576
GO:0005581
GO:0007155
GO:0030020
GO:0030312
GO:0031012
GO:0062023
HMNXSV003012023
ILMN_1768919
ILMN_1845693
ILMN_1889404
ILMN_1906482
PH_hs_0012018
TC03000704.hg
TC03002543.hg
Participates
as a member of
Collagen alpha-5(VI) chains [extracellular region] (Homo sapiens)
Other forms of this molecule
3Hyp-4Hyp-GlcGalHyl-COL6A5 [endoplasmic reticulum lumen]
4Hyp-GalHyl-COL6A5 [endoplasmic reticulum lumen]
GlcGalHyl-COL6A5 [endoplasmic reticulum lumen]
3Hyp-4Hyp-GalHyl-COL6A5 [endoplasmic reticulum lumen]
4Hyp-GlcGalHyl-COL6A5 [endoplasmic reticulum lumen]
GalHyl-COL6A5 [endoplasmic reticulum lumen]
COL6A5 [endoplasmic reticulum lumen]
4Hyp-COL6A5 [endoplasmic reticulum lumen]
3Hyp-4Hyp-COL6A5 [endoplasmic reticulum lumen]
4Hyp-5Hyl-COL6A5 [endoplasmic reticulum lumen]
3Hyp-4Hyp-5Hyl-COL6A5 [endoplasmic reticulum lumen]
5Hyl-COL6A5 [endoplasmic reticulum lumen]
COL6A5(19-?) [extracellular region]
3Hyp-4Hyp-GlcGalHyl-COL6A5(19-?) [extracellular region]
GlcGalHyl-COL6A5(?-2615) [extracellular region]
3Hyp-4Hyp-COL6A5(?-2615) [extracellular region]
4Hyp-GlcGalHyl-COL6A5(?-2615) [extracellular region]
COL6A5(?-2615) [extracellular region]
3Hyp-4Hyp-GalHyl-COL6A5(19-?) [extracellular region]
5Hyl-COL6A5(?-2615) [extracellular region]
4Hyp-5Hyl-COL6A5(?-2615) [extracellular region]
3Hyp-4Hyp-5Hyl-COL6A5(19-?) [extracellular region]
4Hyp-COL6A5(19-?) [extracellular region]
3Hyp-4Hyp-GalHyl-COL6A5(?-2615) [extracellular region]
4Hyp-5Hyl-COL6A5(19-?) [extracellular region]
4Hyp-COL6A5(?-2615) [extracellular region]
4Hyp-GalHyl-COL6A5(?-2615) [extracellular region]
GalHyl-COL6A5(19-?) [extracellular region]
5Hyl-COL6A5(19-?) [extracellular region]
GalHyl-COL6A5(?-2615) [extracellular region]
4Hyp-GalHyl-COL6A5(19-?) [extracellular region]
3Hyp-4Hyp-5Hyl-COL6A5(?-2615) [extracellular region]
3Hyp-4Hyp-5Hyl-COL6A5 [extracellular region]
GalHyl-COL6A5 [extracellular region]
4Hyp-GlcGalHyl-COL6A5 [extracellular region]
4Hyp-5Hyl-COL6A5 [extracellular region]
3Hyp-4Hyp-GalHyl-COL6A5 [extracellular region]
4Hyp-GalHyl-COL6A5 [extracellular region]
4Hyp-COL6A5 [extracellular region]
COL6A5 [extracellular region]
GlcGalHyl-COL6A5 [extracellular region]
3Hyp-4Hyp-GlcGalHyl-COL6A5 [extracellular region]
5Hyl-COL6A5 [extracellular region]
4Hyp-GlcGalHyl-COL6A5(19-?) [extracellular region]
3Hyp-4Hyp-GlcGalHyl-COL6A5(?-2615) [extracellular region]
GlcGalHyl-COL6A5(19-?) [extracellular region]
3Hyp-4Hyp-COL6A5(19-?) [extracellular region]
Inferred To
Homologues of 3Hyp-4Hyp-COL6A5 [extracellular region]
(Caenorhabditis elegans)
COL6A5 [extracellular region]
(Bos taurus)
COL6A5 [extracellular region]
(Sus scrofa)
Col6a5 [extracellular region]
(Mus musculus)
3Hyp-4Hyp-COL6A5 [extracellular region]
(Caenorhabditis elegans)
Modified Residues
Name
(2S,4R)-4-hydroxyproline at unknown position
PsiMod Name
(2S,4R)-4-hydroxyproline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline
Name
(2S,3S)-3-hydroxyproline at unknown position
PsiMod Name
(2S,3S)-3-hydroxyproline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to 3-hydroxy-L-proline.
Cross References
RefSeq
NP_001265227.1
,
NP_694996.5
OpenTargets
ENSG00000172752
GeneCards
A8TX70
Ensembl
ENSP00000422898
,
ENST00000312481
,
ENST00000512836
,
ENSG00000172752
,
ENSP00000309762
PRO
A8TX70
Pharos - Targets
A8TX70
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