Reactome | GalHyl-COL2A1(182-1241) [extracellular region]

GalHyl-COL2A1(182-1241) [extracellular region]

Stable Identifier

R-HSA-2127399

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

GalHyl-COL2A1, 5-Gal-Hyl collagen alpha-1(II) chain, Collagen type II alpha 1 chain, Alpha-1 type II collagen

Locations in the PathwayBrowser

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Developmental Biology (Homo sapiens)

- Developmental Cell Lineages (Homo sapiens)
  - Developmental Cell Lineages of the Exocrine Pancreas (Homo sapiens)
    - Developmental Lineage of Pancreatic Ductal Cells (Homo sapiens)
      - Primary multipotent pancreatic progenitor cell produces trunk bipotent pancreatic progenitor cell (Homo sapiens)
        
        (Laminin, Collagen) [extracellular region] (Homo sapiens)
        
        Collagen fibres [extracellular region] (Homo sapiens)
        
        Collagen type II fibre [extracellular region] (Homo sapiens)
        
        Collagen type II fibril [extracellular region] (Homo sapiens)
        
        Tropocollagen type II [extracellular region] (Homo sapiens)
        
        Collagen alpha-1(II) chains [extracellular region] (Homo sapiens)
        
        GalHyl-COL2A1(182-1241) [extracellular region] (Homo sapiens)
        
        Collagen type XI fibre [extracellular region] (Homo sapiens)
        
        Collagen type XI fibril [extracellular region] (Homo sapiens)
        
        Tropocollagen type XI [extracellular region] (Homo sapiens)
        
        Collagen alpha-1(II) chains [extracellular region] (Homo sapiens)
        
        GalHyl-COL2A1(182-1241) [extracellular region] (Homo sapiens)
      - Trunk bipotent pancreatic progenitor cell produces pancreatic ductal cell (Homo sapiens)
        
        (Laminin, Collagen) [extracellular region] (Homo sapiens)
        
        Collagen fibres [extracellular region] (Homo sapiens)
        
        Collagen type II fibre [extracellular region] (Homo sapiens)
        
        Collagen type II fibril [extracellular region] (Homo sapiens)
        
        Tropocollagen type II [extracellular region] (Homo sapiens)
        
        Collagen alpha-1(II) chains [extracellular region] (Homo sapiens)
        
        GalHyl-COL2A1(182-1241) [extracellular region] (Homo sapiens)
        
        Collagen type XI fibre [extracellular region] (Homo sapiens)
        
        Collagen type XI fibril [extracellular region] (Homo sapiens)
        
        Tropocollagen type XI [extracellular region] (Homo sapiens)
        
        Collagen alpha-1(II) chains [extracellular region] (Homo sapiens)
        
        GalHyl-COL2A1(182-1241) [extracellular region] (Homo sapiens)
- Nervous system development (Homo sapiens)
  - Axon guidance (Homo sapiens)
    - NCAM signaling for neurite out-growth (Homo sapiens)
      - NCAM1 interactions (Homo sapiens)
        
        Interaction of NCAM1 with collagens (Homo sapiens)
        
        Collagens [extracellular region] (Homo sapiens)
        
        Collagen type II fibril [extracellular region] (Homo sapiens)
        
        Tropocollagen type II [extracellular region] (Homo sapiens)
        
        Collagen alpha-1(II) chains [extracellular region] (Homo sapiens)
        
        GalHyl-COL2A1(182-1241) [extracellular region] (Homo sapiens)
        
        NCAM-1:Collagen complex [plasma membrane] (Homo sapiens)
        
        Collagens [extracellular region] (Homo sapiens)
        
        Collagen type II fibril [extracellular region] (Homo sapiens)
        
        Tropocollagen type II [extracellular region] (Homo sapiens)
        
        Collagen alpha-1(II) chains [extracellular region] (Homo sapiens)
        
        GalHyl-COL2A1(182-1241) [extracellular region] (Homo sapiens)

Immune System (Homo sapiens)

- Adaptive Immune System (Homo sapiens)
  - Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell (Homo sapiens)
    - OSCAR binds collagen and SP-D (Homo sapiens)
      - Collagen types I,II,III/SP-D [extracellular region] (Homo sapiens)
        
        Collagen types I,II,III [extracellular region] (Homo sapiens)
        
        Collagen type II fibril [extracellular region] (Homo sapiens)
        
        Tropocollagen type II [extracellular region] (Homo sapiens)
        
        Collagen alpha-1(II) chains [extracellular region] (Homo sapiens)
        
        GalHyl-COL2A1(182-1241) [extracellular region] (Homo sapiens)
      - OSCAR:Collagen I,II,III/SP-D [extracellular region] (Homo sapiens)
        
        Collagen types I,II,III/SP-D [extracellular region] (Homo sapiens)
        
        Collagen types I,II,III [extracellular region] (Homo sapiens)
        
        Collagen type II fibril [extracellular region] (Homo sapiens)
        
        Tropocollagen type II [extracellular region] (Homo sapiens)
        
        Collagen alpha-1(II) chains [extracellular region] (Homo sapiens)
        
        GalHyl-COL2A1(182-1241) [extracellular region] (Homo sapiens)

Signal Transduction (Homo sapiens)

- Signaling by Receptor Tyrosine Kinases (Homo sapiens)
  - Signaling by MET (Homo sapiens)
    - MET promotes cell motility (Homo sapiens)
      - MET activates PTK2 signaling (Homo sapiens)
        
        PTK2 binds activated MET (Homo sapiens)
        
        Integrin alpha2beta1,alpha3:beta1:(collagen,laminin,fibronectin) [plasma membrane] (Homo sapiens)
        
        Collagen, laminin, fibronectin [extracellular region] (Homo sapiens)
        
        Collagen fibres [extracellular region] (Homo sapiens)
        
        Collagen type II fibre [extracellular region] (Homo sapiens)
        
        Collagen type II fibril [extracellular region] (Homo sapiens)
        
        Tropocollagen type II [extracellular region] (Homo sapiens)
        
        Collagen alpha-1(II) chains [extracellular region] (Homo sapiens)
        
        GalHyl-COL2A1(182-1241) [extracellular region] (Homo sapiens)
        
        Collagen type XI fibre [extracellular region] (Homo sapiens)
        
        Collagen type XI fibril [extracellular region] (Homo sapiens)
        
        Tropocollagen type XI [extracellular region] (Homo sapiens)
        
        Collagen alpha-1(II) chains [extracellular region] (Homo sapiens)
        
        GalHyl-COL2A1(182-1241) [extracellular region] (Homo sapiens)
  - Signaling by PDGF (Homo sapiens)
    - PDGF binds to extracellular matrix proteins (Homo sapiens)
      - Extracellular matrix ligands [extracellular region] (Homo sapiens)
        
        Collagens [extracellular region] (Homo sapiens)
        
        Collagen type II fibril [extracellular region] (Homo sapiens)
        
        Tropocollagen type II [extracellular region] (Homo sapiens)
        
        Collagen alpha-1(II) chains [extracellular region] (Homo sapiens)
        
        GalHyl-COL2A1(182-1241) [extracellular region] (Homo sapiens)
      - PDGF A and B chains:ECM complex [extracellular region] (Homo sapiens)
        
        Extracellular matrix ligands [extracellular region] (Homo sapiens)
        
        Collagens [extracellular region] (Homo sapiens)
        
        Collagen type II fibril [extracellular region] (Homo sapiens)
        
        Tropocollagen type II [extracellular region] (Homo sapiens)
        
        Collagen alpha-1(II) chains [extracellular region] (Homo sapiens)
        
        GalHyl-COL2A1(182-1241) [extracellular region] (Homo sapiens)