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TAF3 [nucleoplasm]
Stable Identifier
R-HSA-212446
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
HIV Infection (Homo sapiens)
HIV Life Cycle (Homo sapiens)
Late Phase of HIV Life Cycle (Homo sapiens)
Transcription of the HIV genome (Homo sapiens)
Fall Back to Closed Pre-initiation Complex (Homo sapiens)
HIV-1 closed pre-initiation complex [nucleoplasm] (Homo sapiens)
HIV-1 promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF complex* [nucleoplasm] (Homo sapiens)
HIV-1 promoter:TFIID:TFIIA:TFIIB complex [nucleoplasm] (Homo sapiens)
HIV-1 promoter:TFIID complex [nucleoplasm] (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
HIV-1 open pre-initiation complex [nucleoplasm] (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
HIV Promoter Opening: First Transition (Homo sapiens)
HIV-1 closed pre-initiation complex [nucleoplasm] (Homo sapiens)
HIV-1 promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF complex* [nucleoplasm] (Homo sapiens)
HIV-1 promoter:TFIID:TFIIA:TFIIB complex [nucleoplasm] (Homo sapiens)
HIV-1 promoter:TFIID complex [nucleoplasm] (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
HIV-1 open pre-initiation complex [nucleoplasm] (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
HIV Transcription Initiation (Homo sapiens)
Abortive HIV-1 initiation after formation of the first phosphodiester bond (Homo sapiens)
HIV-1 transcription complex [nucleoplasm] (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
NTP binds active site of RNA Polymerase II in HIV-1 open pre-initiation complex (Homo sapiens)
HIV-1 initiation complex [nucleoplasm] (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
HIV-1 open pre-initiation complex [nucleoplasm] (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
Newly formed phosphodiester bond stabilized and PPi released (Homo sapiens)
HIV-1 initiation complex with phosphodiester-PPi intermediate [nucleoplasm] (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
HIV-1 transcription complex [nucleoplasm] (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
Nucleophillic attack by 3'-hydroxyl oxygen of nascent HIV-1 transcript on the Alpha phosphate of NTP (Homo sapiens)
HIV-1 initiation complex [nucleoplasm] (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
HIV-1 initiation complex with phosphodiester-PPi intermediate [nucleoplasm] (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
RNA Polymerase II HIV Promoter Escape (Homo sapiens)
Abortive HIV-1 Initiation Before Second Transition (Homo sapiens)
HIV-1 Promoter Escape Complex [nucleoplasm] (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
Addition of nucleotides 5 through 9 on the growing HIV-1 transcript (Homo sapiens)
HIV-1 transcription complex containing 4 nucleotide long transcript [nucleoplasm] (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
Addition of the fourth nucleotide on the nascent HIV-1 transcript: Second Transition (Homo sapiens)
HIV-1 transcription complex containing 3 nucleotide long transcript [nucleoplasm] (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
HIV-1 transcription complex containing 4 nucleotide long transcript [nucleoplasm] (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
Addition of the third nucleotide on the nascent HIV-1 transcript (Homo sapiens)
HIV-1 transcription complex [nucleoplasm] (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
HIV-1 transcription complex containing 3 nucleotide long transcript [nucleoplasm] (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
Unwinding of DNA for the nascent HIV-1 transcript (Homo sapiens)
HIV-1 transcription complex [nucleoplasm] (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
Unwinding of DNA for the nascent HIV-1 transcript: Second Transition (Homo sapiens)
HIV-1 transcription complex containing 3 nucleotide long transcript [nucleoplasm] (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional Regulation by TP53 (Homo sapiens)
Regulation of TP53 Activity (Homo sapiens)
Regulation of TP53 Activity through Phosphorylation (Homo sapiens)
TAF1 phosphorylates TP53 (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
RNA Polymerase II Pre-transcription Events (Homo sapiens)
Abortive Initiation Before Second Transition (Homo sapiens)
Pol II Promoter Escape Complex [nucleoplasm] (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
Abortive initiation after formation of the first phosphodiester bond (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
pol II transcription complex [nucleoplasm] (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
Fall Back to Closed Pre-initiation Complex (Homo sapiens)
pol II closed pre-initiation complex [nucleoplasm] (Homo sapiens)
pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF complex [nucleoplasm] (Homo sapiens)
pol II promoter:TFIID:TFIIA:TFIIB complex [nucleoplasm] (Homo sapiens)
pol II promoter:TFIID complex [nucleoplasm] (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
pol II open pre-initiation complex [nucleoplasm] (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
RNA Polymerase II Transcription Initiation And Promoter Clearance (Homo sapiens)
RNA Polymerase II Promoter Escape (Homo sapiens)
Addition of Nucleotides 5 through 9 on the growing Transcript (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
pol II transcription complex containing 4 nucleotide long transcript [nucleoplasm] (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
Addition of the fourth nucleotide on the Nascent Transcript: Second Transition (Homo sapiens)
pol II transcription complex containing 3 Nucleotide long transcript [nucleoplasm] (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
pol II transcription complex containing 4 nucleotide long transcript [nucleoplasm] (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
Addition of the third nucleotide on the nascent transcript (Homo sapiens)
pol II transcription complex [nucleoplasm] (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
pol II transcription complex containing 3 Nucleotide long transcript [nucleoplasm] (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
Unwinding DNA for the nascent transcript (Homo sapiens)
pol II transcription complex [nucleoplasm] (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
Unwinding of DNA for the Nascent Transcript: Second Transition (Homo sapiens)
pol II transcription complex containing 3 Nucleotide long transcript [nucleoplasm] (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
RNA Polymerase II Promoter Opening: First Transition (Homo sapiens)
pol II closed pre-initiation complex [nucleoplasm] (Homo sapiens)
pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF complex [nucleoplasm] (Homo sapiens)
pol II promoter:TFIID:TFIIA:TFIIB complex [nucleoplasm] (Homo sapiens)
pol II promoter:TFIID complex [nucleoplasm] (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
pol II open pre-initiation complex [nucleoplasm] (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
RNA Polymerase II Transcription Initiation (Homo sapiens)
NTP Binds Active Site of RNA Polymerase II (Homo sapiens)
Pol II initiation complex [nucleoplasm] (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
pol II open pre-initiation complex [nucleoplasm] (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
Newly Formed Phosphodiester Bond Stabilized and PPi Released (Homo sapiens)
Pol II Initiation complex with phosphodiester-PPi intermediate [nucleoplasm] (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
pol II transcription complex [nucleoplasm] (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP (Homo sapiens)
Pol II Initiation complex with phosphodiester-PPi intermediate [nucleoplasm] (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
Pol II initiation complex [nucleoplasm] (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening (Homo sapiens)
Binding of TFIIA and TFIIB to the pol II promoter:TFIID complex (Homo sapiens)
pol II promoter:TFIID complex [nucleoplasm] (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
pol II promoter:TFIID:TFIIA:TFIIB complex [nucleoplasm] (Homo sapiens)
pol II promoter:TFIID complex [nucleoplasm] (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
Binding of TFIIE to the growing preinitiation complex (Homo sapiens)
pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF complex [nucleoplasm] (Homo sapiens)
pol II promoter:TFIID:TFIIA:TFIIB complex [nucleoplasm] (Homo sapiens)
pol II promoter:TFIID complex [nucleoplasm] (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF:TFIIE complex [nucleoplasm] (Homo sapiens)
pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF complex [nucleoplasm] (Homo sapiens)
pol II promoter:TFIID:TFIIA:TFIIB complex [nucleoplasm] (Homo sapiens)
pol II promoter:TFIID complex [nucleoplasm] (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
Formation of the closed pre-initiation complex (Homo sapiens)
pol II closed pre-initiation complex [nucleoplasm] (Homo sapiens)
pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF complex [nucleoplasm] (Homo sapiens)
pol II promoter:TFIID:TFIIA:TFIIB complex [nucleoplasm] (Homo sapiens)
pol II promoter:TFIID complex [nucleoplasm] (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF:TFIIE complex [nucleoplasm] (Homo sapiens)
pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF complex [nucleoplasm] (Homo sapiens)
pol II promoter:TFIID:TFIIA:TFIIB complex [nucleoplasm] (Homo sapiens)
pol II promoter:TFIID complex [nucleoplasm] (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
Recognition and Binding of Core Promoter Elements by TFIID (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
pol II promoter:TFIID complex [nucleoplasm] (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex (Homo sapiens)
pol II promoter:TFIID:TFIIA:TFIIB complex [nucleoplasm] (Homo sapiens)
pol II promoter:TFIID complex [nucleoplasm] (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF complex [nucleoplasm] (Homo sapiens)
pol II promoter:TFIID:TFIIA:TFIIB complex [nucleoplasm] (Homo sapiens)
pol II promoter:TFIID complex [nucleoplasm] (Homo sapiens)
TFIID [nucleoplasm] (Homo sapiens)
TAF3 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q5VWG9 TAF3
Gene Names
TAF3
Chain
chain:1-929
Reference Genes
BioGPS Gene:83860 TAF3
COSMIC (genes):TAF3 TAF3
CTD Gene:83860 TAF3
dbSNP Gene:83860 TAF3
ENSEMBL:ENSG00000165632 TAF3
HGNC:17303 TAF3
KEGG:hsa:83860 TAF3
Monarch:83860 TAF3
NCBI Gene:83860 TAF3
OMIM:606576 TAF3
UCSC:Q5VWG9 TAF3
Reference Transcript
RefSeq:NM_031923.3 TAF3
Other Identifiers
11743081_at
11743082_at
11759431_s_at
16702330
235119_PM_at
235119_at
235154_PM_at
235154_at
3234185
3234187
3234188
3234189
3234190
3234193
3234194
3234195
3234213
3234214
3234215
3234216
3234217
3234223
3234224
3234228
3234229
3234230
3234233
3234234
3234235
3234236
3234237
3234255
3746838
45078_at
77003_at
77419_at
7926096
80352_at
82060_at
83860
A_23_P422922
A_24_P508012
A_32_P153892
GE56532
GE86836
GO:0000122
GO:0001673
GO:0002039
GO:0005515
GO:0005634
GO:0005654
GO:0005669
GO:0006351
GO:0006355
GO:0016071
GO:0016251
GO:0031965
GO:0042789
GO:0043226
GO:0043433
GO:0045944
GO:0046872
GO:0046982
GO:0051123
GO:0051457
GO:0060261
GO:0065003
GO:0098772
GO:0140223
GO:0140416
HMNXSV003005035
Hs.130285.0.A1_3p_at
Hs.165433.0.A1_3p_at
PH_hs_0026369
TC10000068.hg
TC10001880.hg
Participates
as a component of
TFIID [nucleoplasm] (Homo sapiens)
Inferred To
TAF3 [nucleoplasm]
(Bos taurus)
TAF3 [nucleoplasm]
(Canis familiaris)
TAF3 [nucleoplasm]
(Gallus gallus)
TAF3 [nucleoplasm]
(Sus scrofa)
Taf3 [nucleoplasm]
(Drosophila melanogaster)
Taf3 [nucleoplasm]
(Mus musculus)
taf-3 [nucleoplasm]
(Caenorhabditis elegans)
taf3 [nucleoplasm]
(Xenopus tropicalis)
Ghost homologue of TAF3 [nucleoplasm]
(Dictyostelium discoideum)
Ghost homologue of TAF3 [nucleoplasm]
(Rattus norvegicus)
Ghost homologue of TAF3 [nucleoplasm]
(Saccharomyces cerevisiae)
Ghost homologue of TAF3 [nucleoplasm]
(Schizosaccharomyces pombe)
Cross References
RefSeq
NP_114129.1
OpenTargets
ENSG00000165632
ENSEMBL
ENST00000344293
,
ENSP00000340271
HPA
ENSG00000165632-TAF3
PRO
Q5VWG9
Pharos - Targets
Q5VWG9
GlyGen
Q5VWG9
PDB
7ENA
,
7ENC
,
5WXG
,
5XMY
,
6MZL
,
5WXH
,
7EGA
,
8GXQ
,
8WAL
,
8WAR
,
5C13
,
7EGC
,
7EGI
,
8GXS
,
7EG9
,
8WAK
,
7EDX
,
7EG8
,
7EGD
,
8WAS
,
7EGJ
,
6MZD
,
7EG7
,
7EGB
,
8WAQ
,
7EGF
,
7EGE
,
8WAN
,
8WAP
,
8WAO
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P84243 H3-3A
18
H3F3A [nucleoplasm]
(R-HSA-212295)
Me2K5-H3F3A [nucleoplasm]
(R-HSA-1214206)
Me3K-28-H3F3A [nucleoplasm]
(R-HSA-212282)
Me3K-10-H3F3A [nucleoplasm]
(R-HSA-5625747)
p-T12,Me3K-10-H3F3A [nucleoplasm]
(R-HSA-5625758)
p-T12, Me2K-10-H3F3A [nucleoplasm]
(R-HSA-5625800)
p-T12,MeK-H3F3A [nucleoplasm]
(R-HSA-5625858)
p-T12-H3F3A [nucleoplasm]
(R-HSA-5625878)
Me2K-10-H3F3A [nucleoplasm]
(R-HSA-427324)
Me3K5-H3F3A [nucleoplasm]
(R-HSA-1214216)
H3F3A [extracellular region]
(R-HSA-977567)
AcK10-H3F3A [nucleoplasm]
(R-HSA-5250654)
Me2K5,Me2aR2-H3F3A [nucleoplasm]
(R-HSA-8936573)
H3R17me2a [nucleoplasm]
(R-HSA-9822613)
MeK28-H3-3A [nucleoplasm]
(R-HSA-9822942)
Me1K5-H3-3A [nucleoplasm]
(R-HSA-9864864)
2xAcK-H3F3A [nucleoplasm]
(R-HSA-427504)
MeK-H3F3A [nucleoplasm]
(R-HSA-427369)
0.544
3
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