NEUROD1- and PDX1-dependent synthesis of glucokinase (GCK) protein

Stable Identifier
R-HSA-211346
Type
Reaction [BlackBoxEvent]
Species
Homo sapiens
Compartment
nucleoplasm, cytosol
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NEUROD1- and PDX1-dependent synthesis of glucokinase (GCK) protein
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The glucokinase (GCK) gene is transcribed and its mRNA is translated. GCK transcription is positively regulated by the activity of the NEUROD1 and PDX1 transcription factors. These events and interactions are inferred from corresponding ones studied in molecular detail in the mouse.

Participants
Input
Output
Participates
as an event of
This event is regulated
Positively by
Regulator
PDX1 [nucleoplasm] (Homo sapiens)
Regulator
NEUROD1 [nucleoplasm] (Homo sapiens)
Inferred From
NeuroD1- and Pdx1-dependent synthesis of glucokinase (Gck) protein (Mus musculus)
Authored
Tello-Ruiz, MK  (2008-05-23)
Ferrer, J  (2008-05-23)
Reviewed
Jensen, J  (2008-05-12)
Created
D'Eustachio, P  (2008-02-01)
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