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Translocation of DFF to the nucleus
Stable Identifier
R-HSA-211206
Type
Reaction [transition]
Species
Homo sapiens
Compartment
nuclear envelope
ReviewStatus
5/5
Locations in the PathwayBrowser
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Programmed Cell Death (Homo sapiens)
Apoptosis (Homo sapiens)
Apoptotic execution phase (Homo sapiens)
Apoptosis induced DNA fragmentation (Homo sapiens)
Translocation of DFF to the nucleus (Homo sapiens)
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
DFF associated with alpha-importin:beta-importin is translocated to the nucleus (Neimanis et al., 2007)
Literature References
PubMed ID
Title
Journal
Year
17938174
Sequence elements in both subunits of the DNA fragmentation factor are essential for its nuclear transport
Kahle, J
,
Neimanis, S
,
Doenecke, D
,
Albig, W
J Biol Chem
2007
Participants
Input
DFF:associated with the importin-alpha:importin-beta complex [cytosol]
(Homo sapiens)
Output
DFF:associated with the importin-alpha:importin-beta complex [nucleoplasm]
(Homo sapiens)
Participates
as an event of
Apoptosis induced DNA fragmentation (Homo sapiens)
Orthologous Events
Translocation of DFF to the nucleus (Bos taurus)
Translocation of DFF to the nucleus (Canis familiaris)
Translocation of DFF to the nucleus (Drosophila melanogaster)
Translocation of DFF to the nucleus (Gallus gallus)
Translocation of DFF to the nucleus (Mus musculus)
Translocation of DFF to the nucleus (Rattus norvegicus)
Translocation of DFF to the nucleus (Sus scrofa)
Translocation of DFF to the nucleus (Xenopus tropicalis)
Authored
Matthews, L (2008-01-29)
Reviewed
Widlak, P (2008-05-08)
Created
Matthews, L (2008-01-29)
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