Reactome | CACNA2D3 [extracellular region]

CACNA2D3 [extracellular region]

Stable Identifier

R-HSA-210402

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

Alpha 2 delta-3 subunit of VGCC

Locations in the PathwayBrowser

Expand all

Neuronal System (Homo sapiens)

- Transmission across Chemical Synapses (Homo sapiens)
  - Presynaptic depolarization and calcium channel opening (Homo sapiens)
    - Ca2+ influx through voltage gated Ca2+ channels (Homo sapiens)
      - Voltage Gated Ca2+ Channel [plasma membrane] (Homo sapiens)
        
        calcium channel multimer of N type VGCC [plasma membrane] (Homo sapiens)
        
        Alpha 2 delta subunits of VGCC [extracellular region] (Homo sapiens)
        
        CACNA2D3 [extracellular region] (Homo sapiens)
        
        calcium channel multimer of P/Q type VGCC [plasma membrane] (Homo sapiens)
        
        Alpha 2 delta subunits of VGCC [extracellular region] (Homo sapiens)
        
        CACNA2D3 [extracellular region] (Homo sapiens)
        
        calcium channel multimer of R type VGCC [plasma membrane] (Homo sapiens)
        
        Alpha 2 delta subunits of VGCC [extracellular region] (Homo sapiens)
        
        CACNA2D3 [extracellular region] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q8IZS8 CACNA2D3

Gene Names

CACNA2D3

Chain

signal peptide:1-28, chain:29-1091, chain:29-, chain:-1091

Reference Genes

BioGPS Gene:55799 CACNA2D3

COSMIC (genes):CACNA2D3 CACNA2D3

CTD Gene:55799 CACNA2D3

dbSNP Gene:55799 CACNA2D3

ENSEMBL:ENSG00000157445 CACNA2D3

ENSEMBL_homo_sapiens_GENE:ENSG00000157445.16 CACNA2D3

HGNC:15460 CACNA2D3

KEGG Gene (Homo sapiens):55799 CACNA2D3

Monarch:55799 CACNA2D3

NCBI Gene:55799 CACNA2D3

OMIM:606399 CACNA2D3

UCSC:Q8IZS8 CACNA2D3

Reference Transcript

RefSeq:NM_018398.2 CACNA2D3

Other Identifiers

11730501_a_at

11746736_a_at

16941885

219714_PM_s_at

219714_s_at

2624640

2624641

2624642

2624643

2624670

2624671

2624677

2624681

2624684

2624685

2624686

2624688

2624695

2624696

2624698

2624699

2624719

2624722

2624728

2624729

2624730

2624737

2624738

2624740

2624743

2624745

2624746

2624747

2624748

2624750

2624751

2624752

2624764

2624765

2624767

2624768

2624772

2624773

2624774

2624777

2624784

2624787

2624789

2624790

55799

63591_at

74322_s_at

8080578

81701_at

A_14_P129304

A_24_P402825

A_33_P3373259

GE55319

GO:0005215

GO:0005245

GO:0005262

GO:0005886

GO:0005891

GO:0006811

GO:0006816

GO:0016020

GO:0034220

GO:0034702

GO:0046872

GO:0055085

GO:0070588

HMNXSV003045308

ILMN_1754076

PH_hs_0033362

TC03000353.hg

g8923764_3p_a_at

Participates

as a candidate of

Alpha 2 delta subunits of VGCC [extracellular region] (Homo sapiens)

Inferred To

CACNA2D3 [extracellular region] (Bos taurus)

CACNA2D3 [extracellular region] (Canis familiaris)

CACNA2D3 [extracellular region] (Gallus gallus)

CACNA2D3 [extracellular region] (Mus musculus)

CACNA2D3 [extracellular region] (Rattus norvegicus)

CACNA2D3 [extracellular region] (Sus scrofa)

stj [extracellular region] (Drosophila melanogaster)

Ca-Ma2d [extracellular region] (Drosophila melanogaster)

Homologues of CACNA2D3 [extracellular region] (Drosophila melanogaster)

stol [extracellular region] (Drosophila melanogaster)

unc-36 [extracellular region] (Caenorhabditis elegans)

Cross References

RefSeq

NP_060868.2

OpenTargets

ENSG00000157445

GeneCards

Q8IZS8

HPA

ENSG00000157445-CACNA2D3

Ensembl

ENSG00000157445, ENST00000490478, ENSP00000418228, ENST00000474759, ENSP00000419101, ENSP00000417279, ENST00000471363

PRO

Q8IZS8

Pharos - Targets

Q8IZS8

Orphanet

28183

HMDB Protein

HMDBP07486