Reactome | WWTR1 (TAZ) binds ZO-2 (TJP2)

WWTR1 (TAZ) binds ZO-2 (TJP2)

Stable Identifier

R-HSA-2064418

Type

Reaction [binding]

Species

Homo sapiens

Compartment

cytosol

ReviewStatus

5/5

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Cytosolic ZO-2 (TJP2) binds WWTR1 (TAZ) to form a complex. This event may play a role in sequestering WWTR1 in the cytosol (Remue et al. 2010). The phosphorylation state of the WWTR1 protein involved in this interaction has not been determined experimentally; it is inferred to be unphosphorylated.

Literature References

PubMed ID	Title	Journal	Year
20850437	TAZ interacts with zonula occludens-1 and -2 proteins in a PDZ-1 dependent manner Meerschaert, K, Vandekerckhove, J, Remue, E, Gettemans, J, Sudol, M, Boucherie, C, Oka, T	FEBS Lett	2010