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Keratan(2)-PRELP [Golgi lumen]
Stable Identifier
R-HSA-2046219
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi lumen
Synonyms
Prolargin, PRELP_HUMAN, PRELP
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of metabolism (Homo sapiens)
Diseases of glycosylation (Homo sapiens)
Diseases associated with glycosaminoglycan metabolism (Homo sapiens)
Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) (Homo sapiens)
Defective B4GALT1 does not transfer Gal to a branch of keratan (Homo sapiens)
Keratan(2)-PG [Golgi lumen] (Homo sapiens)
Keratan(2)-PRELP [Golgi lumen] (Homo sapiens)
Metabolism (Homo sapiens)
Metabolism of carbohydrates (Homo sapiens)
Glycosaminoglycan metabolism (Homo sapiens)
Keratan sulfate/keratin metabolism (Homo sapiens)
Keratan sulfate biosynthesis (Homo sapiens)
B4GALTs transfer Gal to a branch of keratan (Homo sapiens)
Keratan(2)-PG [Golgi lumen] (Homo sapiens)
Keratan(2)-PRELP [Golgi lumen] (Homo sapiens)
B4GALTs transfer Gal to the keratan chain (Homo sapiens)
Keratan(2)-PG [Golgi lumen] (Homo sapiens)
Keratan(2)-PRELP [Golgi lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:P51888 PRELP
Gene Names
PRELP, SLRR2A
Chain
signal peptide:1-20, chain:21-382
Reference Genes
BioGPS Gene:5549 PRELP
COSMIC (genes):PRELP PRELP
CTD Gene:5549 PRELP
dbSNP Gene:5549 PRELP
ENSEMBL:ENSG00000188783 PRELP
ENSEMBL_homo_sapiens_GENE:ENSG00000188783.6 PRELP
HGNC:9357 PRELP
KEGG Gene (Homo sapiens):5549 PRELP
Monarch:5549 PRELP
NCBI Gene:5549 PRELP
OMIM:601914 PRELP
UCSC:P51888 PRELP
Reference Transcript
RefSeq:NM_201348.1 PRELP
RefSeq:NM_002725.3 PRELP
Other Identifiers
11727891_at
11727892_at
11727893_at
11753893_a_at
16676167
204223_PM_at
204223_at
228224_PM_at
228224_at
37022_3p_at
37022_PM_at
37022_at
4053098
4053101
4053102
4053103
4053104
4053106
4053107
4053108
4053109
4053110
4053112
4901389C_3p_s_at
5549
75826_at
7908924
A_23_P51499
A_33_P3234882
GE60535
GO:0001501
GO:0005198
GO:0005201
GO:0005515
GO:0005576
GO:0005615
GO:0005764
GO:0005773
GO:0005794
GO:0005796
GO:0008201
GO:0030021
GO:0030312
GO:0031012
GO:0043202
GO:0043226
GO:0048856
GO:0062023
GO:0070062
GO:0090398
GO:1903561
HMNXSV003028604
Hs.183860.1.A1_3p_at
ILMN_1707380
ILMN_2395156
PH_hs_0027691
RNA147417|p0521_imsncRNA110
TC01001686.hg
U41344_at
g4506040_3p_s_at
Participates
as a member of
Keratan(2)-PG [Golgi lumen] (Homo sapiens)
Other forms of this molecule
PRELP [lysosomal lumen]
KS(2)-PRELP [lysosomal lumen]
KS(2)-PRELP [extracellular region]
KS(2)-PRELP [Golgi lumen]
KS(1)-PRELP [Golgi lumen]
Keratan(4)-PRELP [Golgi lumen]
Keratan(3)-PRELP [Golgi lumen]
Keratan(1)-PRELP [Golgi lumen]
Gal-glycan PRELP [Golgi lumen]
N-glycan PRELP [Golgi lumen]
Inferred To
prelp [Golgi lumen]
(Xenopus tropicalis)
PRELP [Golgi lumen]
(Bos taurus)
PRELP [Golgi lumen]
(Canis familiaris)
PRELP [Golgi lumen]
(Sus scrofa)
Dmel\CG32055 [Golgi lumen]
(Drosophila melanogaster)
Prelp [Golgi lumen]
(Mus musculus)
Prelp [Golgi lumen]
(Rattus norvegicus)
Modified Residues
Name
N4-(N-acetylamino)glucosyl-L-asparagine (ChEBI:63495) at unknown position
Modification
beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-yl group
PsiMod Name
N4-(N-acetylamino)glucosyl-L-asparagine
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.
Cross References
RefSeq
NP_002716.1
,
NP_958505.1
OpenTargets
ENSG00000188783
HPA
ENSG00000188783-PRELP
GeneCards
P51888
Ensembl
ENSP00000343924
,
ENSG00000188783
,
ENST00000343110
PRO
P51888
Pharos - Targets
P51888
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P17707 AMD1
1
AMD1(1-67) [cytosol]
(R-HSA-351223)
0.527
2
UniProt:Q07065 CKAP4
7
CKAP4 [endoplasmic reticulum lumen]
(R-HSA-8956737)
p-CKAP4 [endoplasmic reticulum lumen]
(R-HSA-8956926)
CKAP4 [azurophil granule membrane]
(R-HSA-6799559)
CKAP4 [plasma membrane]
(R-HSA-5686306)
CKAP4 [specific granule membrane]
(R-HSA-6799552)
PALM-C100-CKAP4 [plasma membrane]
(R-HSA-5686280)
PALM-C100-CKAP4 [lamellar body]
(R-HSA-5686285)
0.527
3
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