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Keratan(2)-OMD [Golgi lumen]
Stable Identifier
R-HSA-2046196
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi lumen
Synonyms
Osteomodulin, OMD_HUMAN, OMD
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of metabolism (Homo sapiens)
Diseases of glycosylation (Homo sapiens)
Diseases associated with glycosaminoglycan metabolism (Homo sapiens)
Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) (Homo sapiens)
Defective B4GALT1 does not transfer Gal to a branch of keratan (Homo sapiens)
Keratan(2)-PG [Golgi lumen] (Homo sapiens)
Keratan(2)-OMD [Golgi lumen] (Homo sapiens)
Metabolism (Homo sapiens)
Metabolism of carbohydrates (Homo sapiens)
Glycosaminoglycan metabolism (Homo sapiens)
Keratan sulfate/keratin metabolism (Homo sapiens)
Keratan sulfate biosynthesis (Homo sapiens)
B4GALTs transfer Gal to a branch of keratan (Homo sapiens)
Keratan(2)-PG [Golgi lumen] (Homo sapiens)
Keratan(2)-OMD [Golgi lumen] (Homo sapiens)
B4GALTs transfer Gal to the keratan chain (Homo sapiens)
Keratan(2)-PG [Golgi lumen] (Homo sapiens)
Keratan(2)-OMD [Golgi lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q99983 OMD
Gene Names
OMD, SLRR2C, UNQ190/PRO216
Chain
signal peptide:1-20, chain:21-421
Reference Genes
BioGPS Gene:4958 OMD
COSMIC (genes):OMD OMD
CTD Gene:4958 OMD
dbSNP Gene:4958 OMD
ENSEMBL:ENSG00000127083 OMD
HGNC:8134 OMD
KEGG:hsa:4958 OMD
Monarch:4958 OMD
NCBI Gene:4958 OMD
OMIM:618926 OMD
UCSC:Q99983 OMD
Reference Transcript
RefSeq:NM_005014.2 OMD
Other Identifiers
11728327_at
11728328_at
17095882
205907_PM_s_at
205907_s_at
205908_PM_s_at
205908_s_at
3214820
3214821
3214823
3214824
3214826
3214827
3214828
3214829
3214830
3214831
3214834
41031_at
4958
8162388
AB000114_at
A_23_P94397
GE53008
GO:0005515
GO:0005576
GO:0005615
GO:0005796
GO:0007155
GO:0030312
GO:0031012
GO:0043202
GO:0043226
GO:0070062
HMNXSV003044661
Hs.94070.0.S1_3p_a_at
ILMN_1749846
PH_hs_0005164
TC09001335.hg
g4826875_3p_a_at
Participates
as a member of
Keratan(2)-PG [Golgi lumen] (Homo sapiens)
Other forms of this molecule
N-glycan OMD [Golgi lumen]
Gal-glycan OMD [Golgi lumen]
Keratan(1)-OMD [Golgi lumen]
Keratan(3)-OMD [Golgi lumen]
Keratan(4)-OMD [Golgi lumen]
KS(2)-OMD [Golgi lumen]
KS(1)-OMD [Golgi lumen]
KS(2)-OMD [extracellular region]
OMD [lysosomal lumen]
KS(2)-OMD [lysosomal lumen]
Inferred To
omd [Golgi lumen]
(Xenopus tropicalis)
Omd [Golgi lumen]
(Mus musculus)
Omd [Golgi lumen]
(Rattus norvegicus)
Keratan(2)-OMD [Golgi lumen]
(Gallus gallus)
Dmel\CG32055 [Golgi lumen]
(Drosophila melanogaster)
OMD [Golgi lumen]
(Bos taurus)
OMD [Golgi lumen]
(Canis familiaris)
OMD [Golgi lumen]
(Sus scrofa)
Modified Residues
Name
N4-(N-acetylamino)glucosyl-L-asparagine (ChEBI:63495) at unknown position
Modification
beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-yl group
PsiMod Name
N4-(N-acetylamino)glucosyl-L-asparagine
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.
Cross References
ENSEMBL
ENST00000375550
,
ENSP00000364700
,
ENSP00000516806
,
ENST00000707247
OpenTargets
ENSG00000127083
HPA
ENSG00000127083-OMD
PRO
Q99983
Pharos - Targets
Q99983
HMDB Protein
HMDBP10801
PDB
5YQ5
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