Reactome | TGFBI [plasma membrane]

TGFBI [plasma membrane]

Stable Identifier

R-HSA-204605

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Kerato-epithelin, Transforming growth factor-beta induced protein IG-H3 precursor, BGH3_HUMAN

Locations in the PathwayBrowser

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Metabolism of proteins (Homo sapiens)

- Amyloid fiber formation (Homo sapiens)
  - Amyloid fibrils have additional components (Homo sapiens)
    - Amyloid fibril main peptide chains [extracellular region] (Homo sapiens)
      - Localized amyloid fibril main peptide chains [extracellular region] (Homo sapiens)
        
        Kerato-epithelin amyloid fibril [extracellular region] (Homo sapiens)
        
        TGFBI [plasma membrane] (Homo sapiens)
    - Amyloid fibrils [plasma membrane] (Homo sapiens)
      - Amyloid fibril main peptide chains [extracellular region] (Homo sapiens)
        
        Localized amyloid fibril main peptide chains [extracellular region] (Homo sapiens)
        
        Kerato-epithelin amyloid fibril [extracellular region] (Homo sapiens)
        
        TGFBI [plasma membrane] (Homo sapiens)
  - Amyloid precursor proteins form ordered fibrils (Homo sapiens)
    - Amyloid fibril main peptide chains [extracellular region] (Homo sapiens)
      - Localized amyloid fibril main peptide chains [extracellular region] (Homo sapiens)
        
        Kerato-epithelin amyloid fibril [extracellular region] (Homo sapiens)
        
        TGFBI [plasma membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q15582 TGFBI

Gene Names

TGFBI, BIGH3

Chain

signal peptide:1-23, chain:24-683

Reference Genes

BioGPS Gene:7045 TGFBI

COSMIC (genes):TGFBI TGFBI

CTD Gene:7045 TGFBI

dbSNP Gene:7045 TGFBI

ENSEMBL:ENSG00000120708 TGFBI

HGNC:11771 TGFBI

KEGG Gene (Homo sapiens):7045 TGFBI

Monarch:7045 TGFBI

NCBI Gene:7045 TGFBI

OMIM:601692 TGFBI

UCSC:Q15582 TGFBI

Reference Transcript

RefSeq:NM_000358.2 TGFBI

Other Identifiers

0001850301

11734548_a_at

11734549_s_at

11734550_x_at

11755281_a_at

1385_at

16989496

201506_at

2829948

2829949

2829950

2829951

2829952

2829958

2829959

2829960

2829963

2829964

2829967

2829973

2829974

2829976

2829980

2829982

2829984

2829986

2829989

2829992

2829993

2829994

2829995

68339_at

7045

8108217

A_23_P156327

GE61621

GO:0001525

GO:0002062

GO:0003674

GO:0005178

GO:0005198

GO:0005201

GO:0005515

GO:0005518

GO:0005575

GO:0005576

GO:0005604

GO:0005615

GO:0005622

GO:0005737

GO:0005794

GO:0005802

GO:0005886

GO:0007155

GO:0007162

GO:0007601

GO:0008150

GO:0008283

GO:0030154

GO:0030198

GO:0031012

GO:0042802

GO:0043226

GO:0044267

GO:0048646

GO:0048856

GO:0050839

GO:0050840

GO:0050877

GO:0050896

GO:0062023

GO:0070062

ILMN_1663866

M77349_at

PH_hs_0025144

TC05000682.hg

g4507466_3p_at

Participant Of

repeatedUnit

Kerato-epithelin amyloid fibril [extracellular region]

Other forms of this molecule

TGFBI [extracellular region]

Cross References

RefSeq

NP_000349.1

OpenTargets

ENSG00000120708

GeneCards

Q15582

HPA

ENSG00000120708-TGFBI

Ensembl

ENSG00000120708, ENSP00000416330, ENST00000442011

PRO

Q15582

Orphanet

15609

HMDB Protein

HMDBP07469

PDB

1X3B, 2VXP, 2LTC, 2LTB, 5NV6