Translocation of YAP1 to the nucleus

Stable Identifier
R-HSA-2032770
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

In its unphosphorylated state, the YAP1 transcriptional coactivator moves freely into the nucleus. Phosphorylated YAP1, in contrast, is sequestered in the cytosol (Hao et al. 2008).

Literature References
PubMed ID Title Journal Year
18158288 Tumor suppressor LATS1 is a negative regulator of oncogene YAP

Hao, Y, Chun, A, Cheung, K, Rashidi, B, Yang, X

J Biol Chem 2008
Participants
Participant Of
Orthologous Events
Authored
Reviewed
Created
Cite Us!