OLR1 binds to oxidized LDL

Stable Identifier
Reaction [binding]
Homo sapiens
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The lectin-like oxidized low density lipoprotein receptor- 1 (Lox-1) mediates the recognition and internalization of oxidatively modified low density lipoprotein. This interaction results in a number of pro-atherogenic cellular responses that probably play a significant role in the pathology of atherosclerosis.
Literature References
PubMed ID Title Journal Year
9693095 Identification of the lectin-like receptor for oxidized low-density lipoprotein in human macrophages and its potential role as a scavenger receptor

Yoshida, H, Green, S, Kondratenko, N, Steinberg, D, Quehenberger, O

Biochem J 1998
15000751 Human lectin-like oxidized low-density lipoprotein receptor-1 functions as a dimer in living cells

Tokuyasu, K, Ogawa, S, Xie, Q, Machida, S, Matsunaga, S, Niimi, S, Sakakibara, Y

DNA Cell Biol 2004
9763524 Ligand specificity of LOX-1, a novel endothelial receptor for oxidized low density lipoprotein

Hoshikawa, H, Ochi, H, Sawamura, T, Aoyama, T, Kume, N, Masaki, T, Kita, T, Nishi, E, Moriwaki, H

Arterioscler Thromb Vasc Biol 1998
9052782 An endothelial receptor for oxidized low-density lipoprotein

Tanaka, T, Hoshikawa, H, Miwa, S, Aiba, Y, Sawamura, T, Kume, N, Katsura, Y, Masaki, T, Kita, T, Aoyama, T, Moriwaki, H

Nature 1997
11256994 Characterization of residues and sequences of the carbohydrate recognition domain required for cell surface localization and ligand binding of human lectin-like oxidized LDL receptor

Shi, X, Machida, S, Niimi, S, Ohtani, T

J Cell Sci 2001
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