Phosphorylation of MOB1A and B by p-STK3(MST2)/N

Stable Identifier
R-HSA-2028675
Type
Reaction [transition]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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Cytosolic MOB1A and MOB1B are phosphorylated by phospho-STK3(MST2)/N (Lee et al. 2001). Threonine residues 12 and 35 have been experimentally identifed as the targets of MOB1A phosphorylation; the homologous residues of MOB1B are inferred likewise to be targets.
Literature References
PubMed ID Title Journal Year
11278283 MST, a physiological caspase substrate, highly sensitizes apoptosis both upstream and downstream of caspase activation

Tsubuki, S, Yajima, N, Lee, KK, Ohyama, T, Yonehara, S

J Biol Chem 2001
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Participates
Catalyst Activity

protein serine/threonine kinase activity of p-STK3/N:p-SAV1 [cytosol]

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