Reactome | p-T12,T35-MOB1A [cytosol]

p-T12,T35-MOB1A [cytosol]

Stable Identifier

R-HSA-2028628

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

p-MOB1A, phosphorylated MOB kinase activator 1A

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External Reference Information

External Reference

UniProt:Q9H8S9 MOB1A

Gene Names

MOB1A, C2orf6, MOB4B, MOBK1B, MOBKL1B

Chain

initiator methionine:1, chain:2-216

Reference Genes

BioGPS Gene:55233 MOB1A

COSMIC (genes):MOB1A MOB1A

CTD Gene:55233 MOB1A

dbSNP Gene:55233 MOB1A

ENSEMBL:ENSG00000114978 MOB1A

HGNC:16015 MOB1A

KEGG Gene (Homo sapiens):55233 MOB1A

Monarch:55233 MOB1A

NCBI Gene:55233 MOB1A

OMIM:609281 MOB1A

UCSC:Q9H8S9 MOB1A

Reference Transcript

Other Identifiers

0002570707

11725636_a_at

11758939_at

11758940_at

11758941_x_at

11758942_s_at

16899096

1PI1

201297_s_at

201298_s_at

201299_s_at

214812_s_at

2559804

2559806

2559808

2559809

2559810

2559811

2559812

2559813

2559814

2559815

2559816

2559817

2559820

2559821

2559822

2559828

2559829

37734_at

47088

4J1V

4JIZ

55233

5BRK

5BRM

5TWF

5TWG

5TWH

5XQZ

63789_at

71690

8053064

A_23_P108922

A_24_P379765

A_24_P719081

A_24_P940499

AAH03398

AAX93060

AB016839

AC073263

AJ577474

AK001650

AK021657

AK023321

BAA91810

BAB13868

BAB14525

BAB19058

BC003398

CAE12093

CCDS46340

D80006_at

ENSG00000114978

ENSP00000379364

ENST00000396049

ENST00000396049.4

EntrezGene:55233

EntrezGene:MOB1A

g13097287_3p_a_at

g8922670_3p_a_at

GE88442

GE88617

GO:0003674

GO:0005515

GO:0005575

GO:0005576

GO:0005615

GO:0005622

GO:0005623

GO:0005634

GO:0005730

GO:0005737

GO:0005829

GO:0007165

GO:0008150

GO:0035329

GO:0043167

GO:0043226

GO:0046872

GO:0070062

HGNC:16015

HPA047088

HPA071690

Hs.196437.0.S2_3p_a_at

Hs.322903.0.S1_3p_s_at

ILMN_1731854

ILMN_3242011

IPR005301

IPR036703

MIM:609281

MOB1A

MOB1A-201

NM_001317110

NM_001317111

NM_001317112

NM_018221

NP_001304039

NP_001304040

NP_001304041

NP_060691

PF03637

PH_hs_0011597

SM01388

TC02001993.hg

UPI0000028995

XM_024452973

XP_024308741

Participant Of

hasMember

p-MOB1 [cytosol]

Other forms of this molecule

MOB1A [cytosol]

Inferred To

phospho-p-T12,T35-MOB1A [cytosol] (Bos taurus)

phospho-p-T12,T35-MOB1A [cytosol] (Canis familiaris)

phospho-p-T12,T35-MOB1A [cytosol] (Danio rerio)

phospho-p-T12,T35-MOB1A [cytosol] (Dictyostelium discoideum)

phospho-p-T12,T35-MOB1A [cytosol] (Gallus gallus)

phospho-p-T12,T35-MOB1A [cytosol] (Mus musculus)

phospho-p-T12,T35-MOB1A [cytosol] (Rattus norvegicus)

phospho-p-T12,T35-MOB1A [cytosol] (Sus scrofa)

phospho-p-T12,T35-MOB1A [cytosol] (Xenopus tropicalis)

Modified Residues

Name

O-phospho-L-threonine at 12

Coordinate

PsiMod Name

O-phospho-L-threonine [MOD:00047]

PsiMod Definition

A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.

Name

O-phospho-L-threonine at 35

Coordinate

PsiMod Name

O-phospho-L-threonine [MOD:00047]

PsiMod Definition

A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.

Cross References

RefSeq

NP_001304041.1, NP_060691.2, NP_001304040.1, NP_001304039.1

OpenTargets

ENSG00000114978

GeneCards

Q9H8S9

PRO

Q9H8S9

PDB

1PI1, 5TWG, 5BRK, 6MCQ, 6MCP, 4J1V, 5TWF, 5TWH, 5BRM, 4JIZ, 5XQZ

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q13043 STK4	4	STK4(1-487) [cytosol] (R-HSA-201627) p-T183-STK4(1-487) [cytosol] (R-HSA-2028258) p-T183-STK4(1-326) [cytosol] (R-HSA-2028682) STK4(327-487) [cytosol] (R-HSA-2028668)	0.753	9
UniProt:Q13188 STK3	4	p-T180-STK3(1-491) [cytosol] (R-HSA-2028274) p-T180-STK3(1-322) [cytosol] (R-HSA-2028696) STK3(323-491) [cytosol] (R-HSA-2028684) STK3(1-491) [cytosol] (R-HSA-2028280)	0.642	7