Reactome | p-T12,T35-MOB1A [cytosol]

p-T12,T35-MOB1A [cytosol]

Stable Identifier

R-HSA-2028628

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

p-MOB1A, phosphorylated MOB kinase activator 1A

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External Reference Information

External Reference

UniProt:Q9H8S9 MOB1A

Gene Names

MOB1A, C2orf6, MOB4B, MOBK1B, MOBKL1B

Chain

initiator methionine:1, chain:2-216

Reference Genes

BioGPS Gene:55233 MOB1A

COSMIC (genes):MOB1A MOB1A

CTD Gene:55233 MOB1A

dbSNP Gene:55233 MOB1A

ENSEMBL:ENSG00000114978.18 MOB1A

HGNC:16015 MOB1A

KEGG Gene (Homo sapiens):55233 MOB1A

Monarch:55233 MOB1A

NCBI Gene:55233 MOB1A

OMIM:609281 MOB1A

UCSC:Q9H8S9 MOB1A

Reference Transcript

Other Identifiers

0002570707

11725636_a_at

11758939_at

11758940_at

11758941_x_at

11758942_s_at

16899096

201297_PM_s_at

201297_s_at

201298_PM_s_at

201298_s_at

201299_PM_s_at

201299_s_at

214812_PM_s_at

214812_s_at

2559804

2559806

2559808

2559809

2559810

2559811

2559812

2559813

2559814

2559815

2559816

2559817

2559820

2559821

2559822

2559828

2559829

37734_at

55233

63789_at

8053064

A_23_P108922

A_24_P379765

A_24_P719081

A_24_P940499

D80006_at

GE88442

GE88617

GO:0001934

GO:0005515

GO:0005576

GO:0005615

GO:0005622

GO:0005634

GO:0005654

GO:0005730

GO:0005737

GO:0005829

GO:0007165

GO:0023052

GO:0030295

GO:0032147

GO:0035329

GO:0036211

GO:0043226

GO:0046872

GO:0070062

GO:0098772

HMNXSV003011343

HMNXSV003036832

Hs.196437.0.S2_3p_a_at

Hs.322903.0.S1_3p_s_at

ILMN_1731854

ILMN_3242011

PH_hs_0011597

TC02001993.hg

g13097287_3p_a_at

g8922670_3p_a_at

Participates

as a member of

p-MOB1 [cytosol] (Homo sapiens)

Other forms of this molecule

MOB1A [cytosol]

Inferred To

phospho-p-T12,T35-MOB1A [cytosol] (Canis familiaris)

phospho-p-T12,T35-MOB1A [cytosol] (Danio rerio)

phospho-p-T12,T35-MOB1A [cytosol] (Dictyostelium discoideum)

phospho-p-T12,T35-MOB1A [cytosol] (Drosophila melanogaster)

phospho-p-T12,T35-MOB1A [cytosol] (Mus musculus)

phospho-p-T12,T35-MOB1A [cytosol] (Rattus norvegicus)

phospho-p-T12,T35-MOB1A [cytosol] (Saccharomyces cerevisiae)

phospho-mob-1 [cytosol] (Caenorhabditis elegans)

phospho-MOB1A [cytosol] (Bos taurus)

phospho-MOB1A [cytosol] (Gallus gallus)

phospho-MOB1A [cytosol] (Sus scrofa)

phospho-mob1a [cytosol] (Xenopus tropicalis)

phospho-mob1 [cytosol] (Schizosaccharomyces pombe)

Modified Residues

Name

O-phospho-L-threonine at 12

Coordinate

PsiMod Name

O-phospho-L-threonine [MOD:00047]

PsiMod Definition

A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.

Name

O-phospho-L-threonine at 35

Coordinate

PsiMod Name

O-phospho-L-threonine [MOD:00047]

PsiMod Definition

A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.

Cross References

RefSeq

NP_001304039.1, NP_001304041.1, NP_060691.2, NP_001304040.1

OpenTargets

ENSG00000114978

GeneCards

Q9H8S9

HPA

ENSG00000114978-MOB1A

Ensembl

ENSP00000379364, ENST00000396049, ENSG00000114978

PRO

Q9H8S9

Pharos - Targets

Q9H8S9

PDB

4J1V, 1PI1, 5TWH, 6MCQ, 5BRK, 6MCP, 4JIZ, 5BRM, 5XQZ, 5TWG, 5TWF

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q13043 STK4	4	STK4(1-487) [cytosol] (R-HSA-201627) p-T183-STK4(1-487) [cytosol] (R-HSA-2028258) STK4(327-487) [cytosol] (R-HSA-2028668) p-T183-STK4(1-326) [cytosol] (R-HSA-2028682)	0.747	9
UniProt:Q13188 STK3	4	p-T180-STK3(1-322) [cytosol] (R-HSA-2028696) STK3(323-491) [cytosol] (R-HSA-2028684) p-T180-STK3(1-491) [cytosol] (R-HSA-2028274) STK3(1-491) [cytosol] (R-HSA-2028280)	0.629	7