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p-T12,T35-MOB1A [cytosol]
Stable Identifier
R-HSA-2028628
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
p-MOB1A, phosphorylated MOB kinase activator 1A
Icon
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Hippo (Homo sapiens)
Phosphorylated MOB1A proteins associate with LATS proteins (Homo sapiens)
LATS:p-MOB [cytosol] (Homo sapiens)
p-MOB1 [cytosol] (Homo sapiens)
p-T12,T35-MOB1A [cytosol] (Homo sapiens)
p-MOB1 [cytosol] (Homo sapiens)
p-T12,T35-MOB1A [cytosol] (Homo sapiens)
Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N (Homo sapiens)
LATS:p-MOB [cytosol] (Homo sapiens)
p-MOB1 [cytosol] (Homo sapiens)
p-T12,T35-MOB1A [cytosol] (Homo sapiens)
p-LATS:p-MOB [cytosol] (Homo sapiens)
p-MOB1 [cytosol] (Homo sapiens)
p-T12,T35-MOB1A [cytosol] (Homo sapiens)
Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) (Homo sapiens)
LATS:p-MOB [cytosol] (Homo sapiens)
p-MOB1 [cytosol] (Homo sapiens)
p-T12,T35-MOB1A [cytosol] (Homo sapiens)
p-LATS:p-MOB [cytosol] (Homo sapiens)
p-MOB1 [cytosol] (Homo sapiens)
p-T12,T35-MOB1A [cytosol] (Homo sapiens)
Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) (Homo sapiens)
LATS:p-MOB [cytosol] (Homo sapiens)
p-MOB1 [cytosol] (Homo sapiens)
p-T12,T35-MOB1A [cytosol] (Homo sapiens)
p-LATS:p-MOB [cytosol] (Homo sapiens)
p-MOB1 [cytosol] (Homo sapiens)
p-T12,T35-MOB1A [cytosol] (Homo sapiens)
Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N (Homo sapiens)
LATS:p-MOB [cytosol] (Homo sapiens)
p-MOB1 [cytosol] (Homo sapiens)
p-T12,T35-MOB1A [cytosol] (Homo sapiens)
p-LATS:p-MOB [cytosol] (Homo sapiens)
p-MOB1 [cytosol] (Homo sapiens)
p-T12,T35-MOB1A [cytosol] (Homo sapiens)
Phosphorylation of MOB1A and B by p-STK3 (p-MST2) (Homo sapiens)
p-MOB1 [cytosol] (Homo sapiens)
p-T12,T35-MOB1A [cytosol] (Homo sapiens)
Phosphorylation of MOB1A and B by p-STK3(MST2)/N (Homo sapiens)
p-MOB1 [cytosol] (Homo sapiens)
p-T12,T35-MOB1A [cytosol] (Homo sapiens)
Phosphorylation of MOB1A and B by p-STK4 (p-MST1) (Homo sapiens)
p-MOB1 [cytosol] (Homo sapiens)
p-T12,T35-MOB1A [cytosol] (Homo sapiens)
Phosphorylation of MOB1A and B by p-STK4(MST1)/N (Homo sapiens)
p-MOB1 [cytosol] (Homo sapiens)
p-T12,T35-MOB1A [cytosol] (Homo sapiens)
Phosphorylation of WWTR1 (TAZ) by LATS1 (Homo sapiens)
p-LATS1:p-MOB1 [cytosol] (Homo sapiens)
p-MOB1 [cytosol] (Homo sapiens)
p-T12,T35-MOB1A [cytosol] (Homo sapiens)
Phosphorylation of WWTR1 (TAZ) by LATS2 (Homo sapiens)
p-LATS2:p-MOB1 [cytosol] (Homo sapiens)
p-MOB1 [cytosol] (Homo sapiens)
p-T12,T35-MOB1A [cytosol] (Homo sapiens)
Phosphorylation of YAP by LATS1 (Homo sapiens)
p-LATS1:p-MOB1 [cytosol] (Homo sapiens)
p-MOB1 [cytosol] (Homo sapiens)
p-T12,T35-MOB1A [cytosol] (Homo sapiens)
Phosphorylation of YAP by LATS2 (Homo sapiens)
p-LATS2:p-MOB1 [cytosol] (Homo sapiens)
p-MOB1 [cytosol] (Homo sapiens)
p-T12,T35-MOB1A [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9H8S9 MOB1A
Gene Names
MOB1A, C2orf6, MOB4B, MOBK1B, MOBKL1B
Chain
initiator methionine:, chain:2-216
Reference Genes
BioGPS Gene:55233 MOB1A
COSMIC (genes):MOB1A MOB1A
CTD Gene:55233 MOB1A
dbSNP Gene:55233 MOB1A
ENSEMBL:ENSG00000114978 MOB1A
HGNC:16015 MOB1A
KEGG:hsa:55233 MOB1A
Monarch:55233 MOB1A
NCBI Gene:55233 MOB1A
OMIM:609281 MOB1A
UCSC:Q9H8S9 MOB1A
Reference Transcript
RefSeq:NM_001317112.1 MOB1A
RefSeq:NM_001317110.1 MOB1A
RefSeq:NM_001317111.1 MOB1A
RefSeq:NM_018221.4 MOB1A
Other Identifiers
11725636_a_at
11758939_at
11758940_at
11758941_x_at
11758942_s_at
16899096
201297_PM_s_at
201297_s_at
201298_PM_s_at
201298_s_at
201299_PM_s_at
201299_s_at
214812_PM_s_at
214812_s_at
2559804
2559806
2559808
2559809
2559810
2559811
2559812
2559813
2559814
2559815
2559816
2559817
2559819
2559820
2559821
2559822
2559825
2559826
2559827
2559828
2559829
37734_at
55233
63789_at
8053064
A_23_P108922
A_24_P379765
A_24_P719081
A_24_P940499
D80006_at
GE88442
GE88617
GO:0005515
GO:0005634
GO:0005737
GO:0005829
GO:0030295
GO:0035329
GO:0043226
GO:0043539
GO:0046872
GO:0070062
GO:0098772
HMNXSV003011343
HMNXSV003036832
Hs.196437.0.S2_3p_a_at
Hs.322903.0.S1_3p_s_at
PH_hs_0011597
TC02001993.hg
g13097287_3p_a_at
g8922670_3p_a_at
Participates
as a member of
p-MOB1 [cytosol] (Homo sapiens)
Other forms of this molecule
MOB1A [cytosol]
Inferred To
phospho-p-T12,T35-MOB1A [cytosol]
(Dictyostelium discoideum)
phospho-p-T12,T35-MOB1A [cytosol]
(Drosophila melanogaster)
phospho-p-T12,T35-MOB1A [cytosol]
(Mus musculus)
phospho-p-T12,T35-MOB1A [cytosol]
(Rattus norvegicus)
phospho-p-T12,T35-MOB1A [cytosol]
(Saccharomyces cerevisiae)
phospho-mob-1 [cytosol]
(Caenorhabditis elegans)
phospho-MOB1A [cytosol]
(Bos taurus)
phospho-MOB1A [cytosol]
(Canis familiaris)
phospho-MOB1A [cytosol]
(Gallus gallus)
phospho-MOB1A [cytosol]
(Sus scrofa)
phospho-mob1 [cytosol]
(Schizosaccharomyces pombe)
Modified Residues
Name
O-phospho-L-threonine at 12
Coordinate
12
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-threonine at 35
Coordinate
35
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Cross References
RefSeq
NP_001304041.1
,
NP_001304040.1
,
NP_001304039.1
,
NP_060691.2
ENSEMBL
ENSP00000379364
,
ENST00000396049
OpenTargets
ENSG00000114978
HPA
ENSG00000114978-MOB1A
PRO
Q9H8S9
Pharos - Targets
Q9H8S9
PDB
5BRK
,
4JIZ
,
5XQZ
,
5TWG
,
5TWF
,
1PI1
,
5BRM
,
5TWH
,
6MCQ
,
6MCP
,
4J1V
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q13043 STK4
4
STK4(1-487) [cytosol]
(R-HSA-201627)
STK4(327-487) [cytosol]
(R-HSA-2028668)
p-T183-STK4(1-487) [cytosol]
(R-HSA-2028258)
p-T183-STK4(1-326) [cytosol]
(R-HSA-2028682)
0.747
9
UniProt:Q13188 STK3
4
STK3(1-491) [cytosol]
(R-HSA-2028280)
p-T180-STK3(1-491) [cytosol]
(R-HSA-2028274)
STK3(323-491) [cytosol]
(R-HSA-2028684)
p-T180-STK3(1-322) [cytosol]
(R-HSA-2028696)
0.629
7
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