Reactome | p-SAV1 [cytosol]

p-SAV1 [cytosol]

Stable Identifier

R-HSA-2028276

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

phosphorylated SAV1, phosphorylated Protein salvador homolog 1

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9H4B6 SAV1

Gene Names

SAV1, WW45

Chain

chain:1-383

Reference Genes

BioGPS Gene:60485 SAV1

COSMIC (genes):SAV1 SAV1

CTD Gene:60485 SAV1

dbSNP Gene:60485 SAV1

ENSEMBL:ENSG00000151748 SAV1

HGNC:17795 SAV1

KEGG:hsa:60485 SAV1

Monarch:60485 SAV1

NCBI Gene:60485 SAV1

OMIM:607203 SAV1

UCSC:Q9H4B6 SAV1

Reference Transcript

RefSeq:NM_021818.3 SAV1

Other Identifiers

11722240_a_at

11722241_x_at

11749806_a_at

16792798

218276_PM_s_at

218276_s_at

222573_PM_s_at

222573_s_at

234491_PM_s_at

234491_s_at

238729_PM_x_at

238729_x_at

2787957

3564028

3564029

3564030

3564031

3564032

3564033

3564034

3564035

3564036

3564037

3564041

3564042

3564048

3564049

3564050

3564051

3564052

3564053

3564054

3564055

3564056

3564057

3564058

3564059

42427_i_at

42428_r_at

60485

61871_r_at

65587_at

77275_at

7979033

A_23_P65555

A_24_P287473

GE61843

GO:0001942

GO:0005515

GO:0005634

GO:0005737

GO:0005829

GO:0006915

GO:0007165

GO:0008285

GO:0010468

GO:0012501

GO:0030154

GO:0030216

GO:0035329

GO:0042127

GO:0042802

GO:0043065

GO:0043226

GO:0043539

GO:0045600

GO:0046620

GO:0048856

GO:0050673

GO:0050680

GO:0050821

GO:0060038

GO:0060044

GO:0060090

GO:0060412

GO:0060487

GO:0060575

GO:0097283

GO:0098772

GO:0140537

GO:1902174

GO:2000036

HMNXSV003004185

Hs.155335.0.A1_3p_a_at

Hs.155335.1.A1_3p_a_at

Hs.288906.0.A1_3p_a_at

Hs.288906.1.A1_3p_a_at

ILMN_2050654

PH_hs_0023289

PH_hs_0040761

TC14001122.hg

g11141888_3p_a_at

Participates

as a component of

p-SAV1 dimer [cytosol] (Homo sapiens)

Other forms of this molecule

SAV1 [cytosol]

Inferred To

phospho-sav-1 [cytosol] (Caenorhabditis elegans)

phospho-Sav1 [cytosol] (Mus musculus)

phospho-Sav1 [cytosol] (Rattus norvegicus)

phospho-sav [cytosol] (Drosophila melanogaster)

phospho-sav1 [cytosol] (Danio rerio)

phospho-sav1 [cytosol] (Xenopus tropicalis)

phospho-SAV1 [cytosol] (Bos taurus)

phospho-SAV1 [cytosol] (Canis familiaris)

phospho-SAV1 [cytosol] (Gallus gallus)

phospho-SAV1 [cytosol] (Sus scrofa)

Modified Residues

Name

phosphorylated residue at unknown position

PsiMod Name

phosphorylated residue [MOD:00696]

PsiMod Definition

A protein modification that effectively replaces a hydrogen atom with a phosphate group.

Cross References

ENSEMBL

ENST00000324679, ENSP00000324729, ENSG00000151748

OpenTargets

ENSG00000151748

GeneCards

SAV1

HPA

ENSG00000151748-SAV1

PRO

Q9H4B6

Pharos - Targets

Q9H4B6

PDB

6AO5

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q13188 STK3	4	p-T180-STK3(1-491) [cytosol] (R-HSA-2028274) STK3(1-491) [cytosol] (R-HSA-2028280) STK3(323-491) [cytosol] (R-HSA-2028684) p-T180-STK3(1-322) [cytosol] (R-HSA-2028696)	0.957	29
UniProt:Q13043 STK4	4	p-T183-STK4(1-487) [cytosol] (R-HSA-2028258) STK4(327-487) [cytosol] (R-HSA-2028668) p-T183-STK4(1-326) [cytosol] (R-HSA-2028682) STK4(1-487) [cytosol] (R-HSA-201627)	0.942	23
UniProt:O14544 SOCS6	1	SOCS6 [cytosol] (R-HSA-1469969)	0.527	2
UniProt:P49674 CSNK1E	2	CSNK1E [cytosol] (R-HSA-205877) CSNK1E [nucleoplasm] (R-HSA-421306)	0.527	2
UniProt:Q8TAQ5 ZNF420	2	p-S68-ZNF420 [nucleoplasm] (R-HSA-6799095) ZNF420 [nucleoplasm] (R-HSA-1247509)	0.527	2
UniProt:P18509 ADCYAP1	4	ADCYAP1(132-158) [extracellular region] (R-HSA-420144) ADCYAP1(82-129) [extracellular region] (R-HSA-420254) ADCYAP1(132-169) [extracellular region] (R-HSA-420282) ADCYAP1(2-742) [Golgi membrane] (R-HSA-187679)	0.527	2

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