Integrin alphaXbeta2 binds JAM3

Stable Identifier
R-HSA-202704
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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Although JAM-C is better known for its interaction with MAC-1, an interaction with CD11c/CD18 (known as alpha X beta 2), has also been described.

Literature References
PubMed ID Title Journal Year
17625065 JAM-C regulates unidirectional monocyte transendothelial migration in inflammation

Bradfield, PF, Scheiermann, C, Nourshargh, S, Ody, C, Luscinskas, FW, Rainger, GE, Nash, GB, Miljkovic-Licina, M, Aurrand-Lions, M, Imhof, BA

Blood 2007
12208882 The junctional adhesion molecule 3 (JAM-3) on human platelets is a counterreceptor for the leukocyte integrin Mac-1

Santoso, S, Sachs, UJ, Kroll, H, Linder, M, Ruf, A, Preissner, KT, Chavakis, T

J Exp Med 2002
17525755 The role of junctional adhesion molecules in vascular inflammation

Weber, C, Fraemohs, L, Dejana, E

Nat Rev Immunol 2007
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