Reactome | Integrin alphaXbeta2 binds JAM3

Integrin alphaXbeta2 binds JAM3

Stable Identifier

R-HSA-202704

Type

Reaction [binding]

Species

Homo sapiens

Compartment

plasma membrane

ReviewStatus

5/5

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Although JAM-C is better known for its interaction with MAC-1, an interaction with CD11c/CD18 (known as alpha X beta 2), has also been described.

Literature References

PubMed ID	Title	Journal	Year
12208882	The junctional adhesion molecule 3 (JAM-3) on human platelets is a counterreceptor for the leukocyte integrin Mac-1 Santoso, S, Sachs, UJ, Kroll, H, Linder, M, Ruf, A, Preissner, KT, Chavakis, T	J Exp Med	2002
17625065	JAM-C regulates unidirectional monocyte transendothelial migration in inflammation Bradfield, PF, Scheiermann, C, Nourshargh, S, Ody, C, Luscinskas, FW, Rainger, GE, Nash, GB, Miljkovic-Licina, M, Aurrand-Lions, M, Imhof, BA	Blood	2007
17525755	The role of junctional adhesion molecules in vascular inflammation Weber, C, Fraemohs, L, Dejana, E	Nat Rev Immunol	2007