CD47 binds SIRP

Stable Identifier
R-HSA-202703
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane
ReviewStatus
5/5
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CD47 binds SIRP
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Integrin-associated protein (IAP or CD47) is a receptor for thrombospondin family members, a ligand for the transmembrane signaling protein SIRP-alpha and -gamma, and a component of a supramolecular complex containing specific integrins, heterotrimeric G proteins and cholesterol.

Literature References
PubMed ID Title Journal Year
16691243 The SIRP family of receptors and immune regulation

Barclay, AN, Brown, MH

Nat Rev Immunol 2006
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Orthologous Events
CD47 binds SIRP (Bos taurus)
CD47 binds SIRP (Canis familiaris)
CD47 binds SIRP (Gallus gallus)
CD47 binds SIRP (Mus musculus)
CD47 binds SIRP (Rattus norvegicus)
CD47 binds SIRP (Sus scrofa)
Authored
Ouwehand, WH  (2007-11-12)
Reviewed
Zwaginga, JJ  (2007-11-12)
Created
de Bono, B  (2007-11-11)
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