CD47 binds SIRP

Stable Identifier
R-HSA-202703
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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Integrin-associated protein (IAP or CD47) is a receptor for thrombospondin family members, a ligand for the transmembrane signaling protein SIRP-alpha and -gamma, and a component of a supramolecular complex containing specific integrins, heterotrimeric G proteins and cholesterol.

Literature References
PubMed ID Title Journal Year
16691243 The SIRP family of receptors and immune regulation

Barclay, AN, Brown, MH

Nat Rev Immunol 2006
Participants
Participant Of
Orthologous Events
Authored
Reviewed
Created