Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
Docs
User Guide
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
Data Model
Computational inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyze Data
Species Comparison
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site map
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
Docs
User Guide
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
Data Model
Computational inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyze Data
Species Comparison
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site map
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Download
Search ...
Go!
SLC46A1 [plasma membrane]
Stable Identifier
R-HSA-200673
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Proton-coupled folate transporter
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of vitamins and cofactors (Homo sapiens)
Metabolism of water-soluble vitamins and cofactors (Homo sapiens)
Metabolism of folate and pterines (Homo sapiens)
Cytosolic folate export across the plasma membrane (Homo sapiens)
SLC46A1 [plasma membrane] (Homo sapiens)
Extracellular folate import across the plasma membrane (Homo sapiens)
SLC46A1 [plasma membrane] (Homo sapiens)
Transport of small molecules (Homo sapiens)
Iron uptake and transport (Homo sapiens)
SLC46A1 transports FeHM from extracellular region to cytosol (Homo sapiens)
SLC46A1 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q96NT5 SLC46A1
Gene Names
SLC46A1, HCP1, PCFT
Chain
chain:1-459
Reference Genes
BioGPS Gene:113235 SLC46A1
COSMIC (genes):SLC46A1 SLC46A1
CTD Gene:113235 SLC46A1
dbSNP Gene:113235 SLC46A1
ENSEMBL:ENSG00000076351 SLC46A1
ENSEMBL_homo_sapiens_GENE:ENSG00000076351 SLC46A1
HGNC:30521 SLC46A1
KEGG Gene (Homo sapiens):113235 SLC46A1
Monarch:113235 SLC46A1
NCBI Gene:113235 SLC46A1
OMIM:611672 SLC46A1
UCSC:Q96NT5 SLC46A1
Reference Transcript
RefSeq:NM_001242366.2 SLC46A1
RefSeq:NM_080669.5 SLC46A1
Other Identifiers
0005360746
113235
11614
11736680_a_at
11736681_at
11748455_a_at
1552278_a_at
1552279_a_at
1558703_at
16842618
3750687
3750688
3750689
3750690
3750692
3750693
3750697
3750699
3750701
3750702
3750703
8013616
A0A024QZ15
A0A024QZ44
A_23_P335069
A_24_P159548
AAH10691
ABF47092
AK054669
AK074161
AL832613
BAB70789
BAB84987
BC010691
CAB011614
CAD89945
CCDS74019
CCDS74020
CH471159
DQ496103
EAW51085
EAW51086
EAW51087
EAW51089
ENSG00000076351
ENSP00000480703
ENSP00000483652
ENST00000612814
ENST00000618626
EntrezGene:113235
GO:0003674
GO:0005215
GO:0005542
GO:0005575
GO:0005622
GO:0005623
GO:0005737
GO:0005886
GO:0006810
GO:0006879
GO:0008150
GO:0008517
GO:0009986
GO:0015078
GO:0015232
GO:0015350
GO:0015884
GO:0015886
GO:0016020
GO:0016021
GO:0016324
GO:0022857
GO:0031526
GO:0034641
GO:0042592
GO:0043167
GO:0044281
GO:0046655
GO:0051186
GO:0051958
GO:0055085
GO:0098829
GO:1902600
GO:1904447
HGNC:30521
Hs2.343553.1.S1_3p_a_at
Hs2.343553.1.S2_3p_a_at
ILMN_1673681
IPR005829
IPR011701
IPR020846
IPR036259
J3KTE6
J3QRF7
K7EPJ7
LRG_183
MIM:229050
MIM:611672
NM_001242366
NM_080669
NP_001229295
NP_542400
PF07690
PH_hs_0026128
SLC46A1
SLC46A1-207
SLC46A1-208
TC17001297.hg
uc032ezi.2
uc032ezj.2
UPI0000050394
UPI00000728A8
XM_005277786
XM_017024110
XP_005277843
XP_016879599
Inferred To
SLC46A1 [plasma membrane] (Bos taurus)
SLC46A1 [plasma membrane] (Caenorhabditis elegans)
SLC46A1 [plasma membrane] (Canis familiaris)
SLC46A1 [plasma membrane] (Danio rerio)
SLC46A1 [plasma membrane] (Gallus gallus)
SLC46A1 [plasma membrane] (Mus musculus)
SLC46A1 [plasma membrane] (Rattus norvegicus)
SLC46A1 [plasma membrane] (Sus scrofa)
SLC46A1 [plasma membrane] (Taeniopygia guttata)
SLC46A1 [plasma membrane] (Xenopus tropicalis)
Homologues of SLC46A1 [plasma membrane] (Caenorhabditis elegans)
Cross References
RefSeq
NP_001229295.1
,
NP_542400.2
ZINC - World Drugs
PCFT_HUMAN
OpenTargets
ENSG00000076351
ZINC - FDA approved
PCFT_HUMAN
GeneCards
Q96NT5
ZINC - Substances
PCFT_HUMAN
ZINC target
Q96NT5
ZINC - Biogenic
PCFT_HUMAN
PRO
Q96NT5
ZINC - Predictions - Purchasable
PCFT_HUMAN
Orphanet
16874
HMDB Protein
HMDBP03060
© 2019
Reactome