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SLC46A1 [plasma membrane]
Stable Identifier
R-HSA-200673
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Proton-coupled folate transporter
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Heme signaling (Homo sapiens)
SLC46A1 transports hemes from extracellular region to cytosol (Homo sapiens)
SLC46A1 [plasma membrane] (Homo sapiens)
Metabolism (Homo sapiens)
Metabolism of vitamins and cofactors (Homo sapiens)
Metabolism of water-soluble vitamins and cofactors (Homo sapiens)
Metabolism of folate and pterines (Homo sapiens)
Cytosolic folate export across the plasma membrane (Homo sapiens)
SLC46A1 [plasma membrane] (Homo sapiens)
SLC46A1 transports FOLA from extracellular region to cytosol (Homo sapiens)
SLC46A1 [plasma membrane] (Homo sapiens)
Transport of small molecules (Homo sapiens)
Iron uptake and transport (Homo sapiens)
SLC46A1 transports hemes from extracellular region to cytosol (Homo sapiens)
SLC46A1 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q96NT5 SLC46A1
Gene Names
SLC46A1, G21, HCP1, PCFT
Chain
chain:1-459
Reference Genes
BioGPS Gene:113235 SLC46A1
COSMIC (genes):SLC46A1 SLC46A1
CTD Gene:113235 SLC46A1
dbSNP Gene:113235 SLC46A1
ENSEMBL:ENSG00000076351 SLC46A1
HGNC:30521 SLC46A1
KEGG:hsa:113235 SLC46A1
Monarch:113235 SLC46A1
NCBI Gene:113235 SLC46A1
OMIM:611672 SLC46A1
UCSC:Q96NT5 SLC46A1
Reference Transcript
RefSeq:NM_080669.5 SLC46A1
RefSeq:NM_001242366.2 SLC46A1
Other Identifiers
113235
11736680_a_at
11736681_at
11748455_a_at
1552278_PM_a_at
1552278_a_at
1552279_PM_a_at
1552279_a_at
1558703_PM_at
1558703_at
16842618
3750684
3750686
3750687
3750688
3750689
3750690
3750691
3750692
3750693
3750694
3750697
3750698
3750699
3750701
3750702
3750703
3750704
3750705
51553_at
8013616
A_23_P335069
A_24_P159548
A_33_P3235611
GO:0005215
GO:0005542
GO:0005737
GO:0005768
GO:0005886
GO:0006575
GO:0006766
GO:0006879
GO:0008517
GO:0009986
GO:0010008
GO:0015078
GO:0015232
GO:0015293
GO:0015350
GO:0015884
GO:0015886
GO:0016020
GO:0016323
GO:0016324
GO:0022600
GO:0022857
GO:0031410
GO:0031526
GO:0042168
GO:0043226
GO:0046655
GO:0051958
GO:0055085
GO:0098829
GO:0098838
GO:0140211
GO:1902600
GO:1904447
HMNXSV003001322
HMNXSV003026420
Hs2.343553.1.S1_3p_a_at
Hs2.343553.1.S2_3p_a_at
Hs2.343553.2.S1_3p_at
ILMN_1673681
PH_hs_0026128
TC17001297.hg
Inferred To
slcr-46.3 [plasma membrane]
(Caenorhabditis elegans)
Dmel\CG15890 [plasma membrane]
(Drosophila melanogaster)
CG8054 [plasma membrane]
(Drosophila melanogaster)
SLC46A1 [plasma membrane]
(Bos taurus)
SLC46A1 [plasma membrane]
(Canis familiaris)
SLC46A1 [plasma membrane]
(Danio rerio)
SLC46A1 [plasma membrane]
(Gallus gallus)
SLC46A1 [plasma membrane]
(Mus musculus)
SLC46A1 [plasma membrane]
(Rattus norvegicus)
SLC46A1 [plasma membrane]
(Saccharomyces cerevisiae)
SLC46A1 [plasma membrane]
(Schizosaccharomyces pombe)
SLC46A1 [plasma membrane]
(Sus scrofa)
BcDNA:RH31685 [plasma membrane]
(Drosophila melanogaster)
slcr-46.1 [plasma membrane]
(Caenorhabditis elegans)
Dmel\CG15553 [plasma membrane]
(Drosophila melanogaster)
Dmel\CG8008 [plasma membrane]
(Drosophila melanogaster)
Dmel\CG30345 [plasma membrane]
(Drosophila melanogaster)
AC [plasma membrane]
(Drosophila melanogaster)
slc46a1 [plasma membrane]
(Xenopus tropicalis)
slcr-46.2 [plasma membrane]
(Caenorhabditis elegans)
SLC46 [plasma membrane]
(Drosophila melanogaster)
Homologues of SLC46A1 [plasma membrane]
(Caenorhabditis elegans)
Homologues of SLC46A1 [plasma membrane]
(Drosophila melanogaster)
slc-46a [plasma membrane]
(Caenorhabditis elegans)
Cross References
RefSeq
NP_542400.2
,
NP_001229295.1
ZINC - World Drugs
PCFT_HUMAN
Guide to Pharmacology - Targets
1213
ENSEMBL
ENST00000612814
,
ENSP00000483652
,
ENST00000618626
,
ENSP00000480703
OpenTargets
ENSG00000076351
ZINC - FDA approved
PCFT_HUMAN
ZINC - Substances
PCFT_HUMAN
ZINC - Biogenic
PCFT_HUMAN
ZINC target
Q96NT5
PRO
Q96NT5
GlyGen
Q96NT5
HPA
ENSG00000076351-SLC46A1
Pharos - Targets
Q96NT5
Orphanet
SLC46A1
ZINC - Predictions - Purchasable
PCFT_HUMAN
HMDB Protein
HMDBP03060
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