LILR-binding HLA Class I

Stable Identifier
R-HSA-199591
Type
Set [CandidateSet]
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
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Summation

A number of MHC Class I molecules a known bind differentially to LILRs, and many more interactions are being explored. This 'Candidate Set' of Class I molecules will be periodically revised as more clear-cut binding affinities emerge from this experimental work.

Literature References
PubMed ID Title Journal Year
15304001 The LILR family: modulators of innate and adaptive immune pathways in health and disease

Brown, D, Trowsdale, J, Allen, R

Tissue Antigens 2004
9842885 The MHC class I binding proteins LIR-1 and LIR-2 inhibit Fc receptor-mediated signaling in monocytes

Fanger, NA, Cosman, D, Peterson, L, Braddy, SC, Maliszewski, CR, Borges, L

Eur J Immunol 1998
Participants
members
candidates
Participant Of
hasComponent