CYB5A:heme reduces Asc.- to AscH-

Stable Identifier
R-HSA-198845
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Synonyms
Reduction of semidehydroascorbate to ascorbate
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The reduction of cytosolic semidehydroascorbate (SDA) to ascorbate (AscH-) is catalyzed by cytochrome B5 (CYB5A) associated with the mitochondrial outer membrane. In the course of the reaction, the heme iron of the cytochrome is oxidized (Linster & Van Schaftingen 2007, Shirabe et al. 1995).

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
aldo-keto reductase (NADP) activity of CYB5A:heme [mitochondrial outer membrane]
Physical Entity
Activity
Orthologous Events
Authored
Created