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SIGLEC8 [plasma membrane]
Stable Identifier
R-HSA-197720
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Sialic acid binding Ig-like lectin 8 precursor, SIL8_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell (Homo sapiens)
Sialic acid binds SIGLEC (Homo sapiens)
SIGLEC [plasma membrane] (Homo sapiens)
SIGLEC8 [plasma membrane] (Homo sapiens)
SIGLEC:sialic acid [plasma membrane] (Homo sapiens)
SIGLEC [plasma membrane] (Homo sapiens)
SIGLEC8 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9NYZ4 SIGLEC8
Gene Names
SIGLEC8, SAF2
Chain
signal peptide:1-16, chain:17-499
Reference Genes
BioGPS Gene:27181 SIGLEC8
COSMIC (genes):SIGLEC8 SIGLEC8
CTD Gene:27181 SIGLEC8
dbSNP Gene:27181 SIGLEC8
ENSEMBL:ENSG00000105366 SIGLEC8
ENSEMBL_homo_sapiens_GENE:ENSG00000105366.15 SIGLEC8
HGNC:10877 SIGLEC8
KEGG Gene (Homo sapiens):27181 SIGLEC8
Monarch:27181 SIGLEC8
NCBI Gene:27181 SIGLEC8
OMIM:605639 SIGLEC8
UCSC:Q9NYZ4 SIGLEC8
Reference Transcript
RefSeq:NM_014442.2 SIGLEC8
RefSeq:XM_011526735.2 SIGLEC8
Other Identifiers
11735266_a_at
11735267_at
11750637_a_at
11751435_a_at
11751436_x_at
11762725_at
16874866
208253_3p_at
208253_PM_at
208253_at
216327_PM_s_at
216327_s_at
216328_PM_at
216328_at
27181
3839629
3839633
3839652
3869063
3869064
3869065
3869068
3869069
3869070
3869071
3869072
3869073
3869074
3869075
3869076
3869077
3869084
3869088
8038839
A_24_P40001
GE79897
GO:0004888
GO:0005515
GO:0005886
GO:0007155
GO:0007165
GO:0016020
GO:0023052
GO:0030246
GO:0033691
GO:0060089
HMNXSV003037800
Hs.279751.1.S1_3p_at
ILMN_1730295
PH_hs_0026177
TC19001780.hg
g7657571_3p_at
g7657571_3p_x_at
Participates
as a candidate of
SIGLEC [plasma membrane] (Homo sapiens)
Inferred To
XB5961956 [plasma membrane]
(Xenopus tropicalis)
LOC110261034 [plasma membrane]
(Sus scrofa)
siglecl2 [plasma membrane]
(Xenopus tropicalis)
LOC119881386 [plasma membrane]
(Canis familiaris)
Homologues of SIGLEC8 [plasma membrane]
(Bos taurus)
Homologues of SIGLEC8 [plasma membrane]
(Canis familiaris)
Homologues of SIGLEC8 [plasma membrane]
(Sus scrofa)
Homologues of SIGLEC8 [plasma membrane]
(Xenopus tropicalis)
LOC102152131 [plasma membrane]
(Canis familiaris)
Siglec8 [plasma membrane]
(Rattus norvegicus)
LOC100138951 [plasma membrane]
(Bos taurus)
LOC618268 [plasma membrane]
(Bos taurus)
LOC618463 [plasma membrane]
(Bos taurus)
mag [plasma membrane]
(Danio rerio)
LOC100515551 [plasma membrane]
(Sus scrofa)
LOC484343 [plasma membrane]
(Canis familiaris)
LOC100686511 [plasma membrane]
(Canis familiaris)
SIGLEC11 [plasma membrane]
(Bos taurus)
SIGLEC11 [plasma membrane]
(Canis familiaris)
SIGLEC8 [plasma membrane]
(Bos taurus)
SIGLEC8 [plasma membrane]
(Mus musculus)
SIGLEC8 [plasma membrane]
(Sus scrofa)
Cross References
RefSeq
XP_011525037.1
,
NP_055257.2
Guide to Pharmacology - Targets
3012
OpenTargets
ENSG00000105366
GeneCards
Q9NYZ4
HPA
ENSG00000105366-SIGLEC8
Ensembl
ENST00000340550
,
ENSP00000321077
,
ENSG00000105366
,
ENST00000321424
,
ENSP00000339448
PRO
Q9NYZ4
Pharos - Targets
Q9NYZ4
PDB
2N7B
,
7QUH
,
7QUI
,
7QU6
,
2N7A
HMDB Protein
HMDBP14210
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P04155 TFF1
1
TFF1 [extracellular region]
(R-HSA-9017879)
0.544
3
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