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TYRO3 [plasma membrane]
Stable Identifier
R-HSA-197626
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Tyrosine-protein kinase receptor TYRO3 precursor, TYO3_HUMAN, Sky
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
Dengue Virus Infection (Homo sapiens)
Dengue Virus Attachment and Entry (Homo sapiens)
Dengue virion envelope phosphatidylserine binds liganded TAM-family receptor (Homo sapiens)
DENV-2 virion:TAM receptor ligands:TAM receptor [plasma membrane] (Homo sapiens)
TAM receptors:TAM receptor ligands [plasma membrane] (Homo sapiens)
TAM family receptors [plasma membrane] (Homo sapiens)
TYRO3 [plasma membrane] (Homo sapiens)
TAM receptors:TAM receptor ligands [plasma membrane] (Homo sapiens)
TAM family receptors [plasma membrane] (Homo sapiens)
TYRO3 [plasma membrane] (Homo sapiens)
Dengue virion gets internalized (Homo sapiens)
DENV receptors [plasma membrane] (Homo sapiens)
TAM family receptors [plasma membrane] (Homo sapiens)
TYRO3 [plasma membrane] (Homo sapiens)
DENV-2 virion:Receptor [plasma membrane] (Homo sapiens)
DENV-2 virion:TAM receptor ligands:TAM receptor [plasma membrane] (Homo sapiens)
TAM receptors:TAM receptor ligands [plasma membrane] (Homo sapiens)
TAM family receptors [plasma membrane] (Homo sapiens)
TYRO3 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q06418 TYRO3
Gene Names
TYRO3, BYK, DTK, RSE, SKY, TIF
Chain
signal peptide:1-40, chain:41-890
Reference Genes
BioGPS Gene:7301 TYRO3
COSMIC - genes:TYRO3 TYRO3
CTD Gene:7301 TYRO3
dbSNP Gene:7301 TYRO3
ENSEMBL:ENSG00000092445 TYRO3
HGNC:12446 TYRO3
KEGG:hsa:7301 TYRO3
Monarch:7301 TYRO3
NCBI Gene:7301 TYRO3
OMIM:600341 TYRO3
UCSC:Q06418 TYRO3
Reference Transcript
RefSeq:NM_001330264.1 TYRO3
RefSeq:NM_006293.3 TYRO3
Other Identifiers
1063_s_at
11722101_a_at
11722102_a_at
1399_at
16799852
17121176
2086_s_at
211431_PM_s_at
211431_s_at
211432_PM_s_at
211432_s_at
3140841
3140844
3140847
35246_at
3590502
3590503
3590504
3590505
3590506
3590507
3590508
3590509
3590511
3590512
3590513
3590514
3590515
3590516
3590517
3590518
3590520
3590521
3590522
3590523
3590524
3590525
3590526
3590527
3590528
3590529
3590530
3590531
3590532
3590533
3590534
3590535
3590536
3590537
3590538
3590539
3590544
3590545
3590547
3633817
3633823
3633828
3633832
3633834
3904613
7301
7982935
7982938
8180298
A_14_P112523
A_23_P54517
A_32_P191285
A_32_P32923
GE58986
GO:0000166
GO:0001618
GO:0001764
GO:0001779
GO:0002376
GO:0003824
GO:0004672
GO:0004713
GO:0004714
GO:0005515
GO:0005524
GO:0005634
GO:0005635
GO:0005789
GO:0005886
GO:0006468
GO:0006909
GO:0007155
GO:0007165
GO:0007169
GO:0007218
GO:0007283
GO:0007399
GO:0009986
GO:0016020
GO:0016192
GO:0016301
GO:0016477
GO:0016740
GO:0021885
GO:0022414
GO:0030154
GO:0030168
GO:0032940
GO:0034122
GO:0034446
GO:0042698
GO:0043235
GO:0043277
GO:0043491
GO:0043524
GO:0043548
GO:0045824
GO:0046649
GO:0046718
GO:0046872
GO:0048856
GO:0048870
GO:0050728
GO:0051250
GO:0051402
GO:0051649
GO:0051897
GO:0060068
GO:0070050
GO:0070527
GO:0140096
GO:1903902
HMNXSV003036839
ILMN_1740169
PH_hs_0024341
TC15000310.hg
TC15002166.hg
U02566_s_at
U18934_at
g2329844_3p_a_at
g463469_3p_a_at
Participates
as a member of
TAM family receptors [plasma membrane] (Homo sapiens)
Other forms of this molecule
TYRO3 [endosome membrane]
Cross References
RefSeq
NP_006284.2
,
NP_001317193.1
ZINC - World Drugs
TYRO3_HUMAN
Guide to Pharmacology - Targets
1836
ENSEMBL
ENST00000263798
,
ENSP00000263798
,
ENSG00000092445
OpenTargets
ENSG00000092445
ZINC - FDA approved
TYRO3_HUMAN
ZINC - Substances
TYRO3_HUMAN
ZINC - Biogenic
TYRO3_HUMAN
ZINC target
Q06418
PRO
Q06418
PDB
1RHF
ZINC - Investigational
TYRO3_HUMAN
IntEnz
2.7.10.1
GeneCards
TYRO3
HPA
ENSG00000092445-TYRO3
Pharos - Targets
Q06418
ZINC - Predictions - Purchasable
TYRO3_HUMAN
HMDB Protein
HMDBP01218
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P62993 GRB2
1
GRB2 [cytosol]
(R-HSA-8983328)
0.666
4
UniProt:P08238 HSP90AB1
6
HSP90AB1 [lysosomal lumen]
(R-HSA-9622846)
HSP90AB1 [nucleoplasm]
(R-HSA-5082399)
HSP90AB1 [cytosol]
(R-HSA-419617)
HSP90AB1 [ficolin-1-rich granule lumen]
(R-HSA-6801491)
HSP90AB1 [extracellular region]
(R-HSA-6806463)
HSP90AB1 [secretory granule lumen]
(R-HSA-6801477)
0.564
2
UniProt:Q9H8X2 IPPK
2
IPPK [cytosol]
(R-HSA-1604598)
IPPK [nucleoplasm]
(R-HSA-2023949)
0.527
2
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