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CYP11B2 [mitochondrial inner membrane]
Stable Identifier
R-HSA-194019
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
mitochondrial inner membrane
Synonyms
Cytochrome P450 11B2, CPN2_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Biological oxidations (Homo sapiens)
Phase I - Functionalization of compounds (Homo sapiens)
Cytochrome P450 - arranged by substrate type (Homo sapiens)
Endogenous sterols (Homo sapiens)
CYP11B1 oxidises 11DCORT (Homo sapiens)
Cytochrome P450 (CYP11B1 based) [mitochondrial inner membrane] (Homo sapiens)
CYP11B2 [mitochondrial inner membrane] (Homo sapiens)
CYP11B2 18-hydroxylates CORST to 18HCORST (Homo sapiens)
CYP11B2 [mitochondrial inner membrane] (Homo sapiens)
CYP11B2 oxidises 11DCORST to CORST (Homo sapiens)
CYP11B2 [mitochondrial inner membrane] (Homo sapiens)
CYP11B2 oxidises 18HCORST to ALDO (Homo sapiens)
CYP11B2 [mitochondrial inner membrane] (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Metabolism of steroids (Homo sapiens)
Metabolism of steroid hormones (Homo sapiens)
Glucocorticoid biosynthesis (Homo sapiens)
CYP11B1 oxidises 11DCORT (Homo sapiens)
Cytochrome P450 (CYP11B1 based) [mitochondrial inner membrane] (Homo sapiens)
CYP11B2 [mitochondrial inner membrane] (Homo sapiens)
Mineralocorticoid biosynthesis (Homo sapiens)
CYP11B2 18-hydroxylates CORST to 18HCORST (Homo sapiens)
CYP11B2 [mitochondrial inner membrane] (Homo sapiens)
CYP11B2 oxidises 11DCORST to CORST (Homo sapiens)
CYP11B2 [mitochondrial inner membrane] (Homo sapiens)
CYP11B2 oxidises 18HCORST to ALDO (Homo sapiens)
CYP11B2 [mitochondrial inner membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P19099 CYP11B2
Gene Names
CYP11B2
Chain
transit peptide:1-24, chain:25-503
Reference Genes
BioGPS Gene:1585 CYP11B2
COSMIC (genes):CYP11B2 CYP11B2
CTD Gene:1585 CYP11B2
dbSNP Gene:1585 CYP11B2
ENSEMBL:ENSG00000179142 CYP11B2
HGNC:2592 CYP11B2
Monarch:1585 CYP11B2
NCBI Gene:1585 CYP11B2
OMIM:124080 CYP11B2
UCSC:P19099 CYP11B2
Reference Transcript
RefSeq:NM_000498.3 CYP11B2
Other Identifiers
11742070_at
1412_g_at
1585
17082001
214630_3p_at
214630_PM_at
214630_at
3157221
3157223
3157226
3157232
3157234
3157242
3157243
3157244
3157245
3157246
3157247
3157248
3157249
3157251
3157253
3157254
3157255
3157256
3157257
3157258
3157259
3157260
32342_at
34549_g_at
8153373
A_23_P215997
GE59810
GO:0002017
GO:0003014
GO:0003091
GO:0003824
GO:0004497
GO:0004507
GO:0005506
GO:0005739
GO:0005743
GO:0006629
GO:0006694
GO:0006700
GO:0006704
GO:0006705
GO:0008203
GO:0008395
GO:0016125
GO:0016491
GO:0016705
GO:0020037
GO:0032342
GO:0032870
GO:0034650
GO:0034651
GO:0035865
GO:0043226
GO:0046872
GO:0047783
GO:0050886
GO:0055075
GO:0055078
GO:0071375
GO:1901615
HMNXSV003012949
Hs.184927.0.S2_3p_at
Hs.184927.0.S2_3p_x_at
Hs2.377912.1.S1_3p_s_at
ILMN_1752099
M32879_s_at
PH_hs_0034248
TC08001709.hg
X54741_at
Participates
as a candidate of
Cytochrome P450 (CYP11B1 based) [mitochondrial inner membrane] (Homo sapiens)
Other forms of this molecule
CYP11B2 T498A [mitochondrial inner membrane]
CYP11B2 E255* [mitochondrial inner membrane]
CYP11B2 L461P [mitochondrial inner membrane]
CYP11B2 R181W [mitochondrial inner membrane]
CYP11B2 R141_L142dup [mitochondrial inner membrane]
CYP11B2 T185I [mitochondrial inner membrane]
CYP11B2 V386A [mitochondrial inner membrane]
Inferred To
CYP11B2 [mitochondrial inner membrane]
(Bos taurus)
CYP11B2 [mitochondrial inner membrane]
(Canis familiaris)
CYP11B2 [mitochondrial inner membrane]
(Mus musculus)
CYP11B2 [mitochondrial inner membrane]
(Rattus norvegicus)
CYP11B2 [mitochondrial inner membrane]
(Sus scrofa)
CYP11B2 [mitochondrial inner membrane]
(Xenopus tropicalis)
Cross References
ZINC - World Drugs
C11B2_HUMAN
Guide to Pharmacology - Targets
1360
OpenTargets
ENSG00000179142
ENSEMBL
ENSP00000325822
,
ENST00000323110
ZINC - FDA approved
C11B2_HUMAN
ZINC - Substances
C11B2_HUMAN
ZINC - Biogenic
C11B2_HUMAN
ZINC target
P19099
PRO
P19099
PDB
7M8V
,
7M8I
,
6XZ9
,
6XZ8
,
4ZGX
,
4DVQ
,
4FDH
ZINC - Investigational
C11B2_HUMAN
IntEnz
1.14.15.5
HPA
ENSG00000179142-CYP11B2
Pharos - Targets
P19099
ZINC - Predictions - Purchasable
C11B2_HUMAN
Orphanet
CYP11B2
HMDB Protein
HMDBP05268
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