Digestion of triacylglycerols by extracellular pancreatic lipase-related protein 2

Stable Identifier
R-HSA-192475
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Pancreatic lipase-related protein 2 catalyzes the hydrolysis of extracellular triacylglycerols to yield diacylglycerols and free long-chain fatty acids. This enzyme, unlike the closely related pancreatic lipase protein, does not require colipase protein for activity. The protein is synthesized in the pancreas, but its role in the digestion of dietary fat has not been established (Giller et al. 1992).

Literature References
PubMed ID Title Journal Year
1379598 Two novel human pancreatic lipase related proteins, hPLRP1 and hPLRP2. Differences in colipase dependence and in lipase activity.

Giller, T, Buchwald, P, Blum-Kaelin, D, Hunziker, W

J Biol Chem 1992
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
acylglycerol lipase activity of PNLIPRP2-like proteins [extracellular region]
Physical Entity
Activity
Orthologous Events
Authored
Created
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