Reactome | Digestion of triacylglycerols by extracellular pancreatic lipase-related protein 2

Digestion of triacylglycerols by extracellular pancreatic lipase-related protein 2

Stable Identifier

R-HSA-192475

Type

Reaction [transition]

Species

Homo sapiens

Compartment

extracellular region

ReviewStatus

5/5

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Digestion of triacylglycerols by extracellular pancreatic lipase-related protein 2

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Pancreatic lipase-related protein 2 catalyzes the hydrolysis of extracellular triacylglycerols to yield diacylglycerols and free long-chain fatty acids. This enzyme, unlike the closely related pancreatic lipase protein, does not require colipase protein for activity. The protein is synthesized in the pancreas, but its role in the digestion of dietary fat has not been established (Giller et al. 1992).

Literature References

PubMed ID	Title	Journal	Year
1379598	Two novel human pancreatic lipase related proteins, hPLRP1 and hPLRP2. Differences in colipase dependence and in lipase activity. Buchwald, P, Giller, T, Hunziker, W, Blum-Kaelin, D	J Biol Chem	1992