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Association of Golgi transport vesicles with microtubules
Stable Identifier
R-HSA-190520
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
Locations in the PathwayBrowser
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Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Gap junction trafficking and regulation (Homo sapiens)
Gap junction trafficking (Homo sapiens)
Gap junction assembly (Homo sapiens)
Transport of connexons to the plasma membrane (Homo sapiens)
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane (Homo sapiens)
Association of Golgi transport vesicles with microtubules (Homo sapiens)
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
One mechanism of transport of connexon-containing vesicles involves movement along microtubules (Segretain and Falk, 2004). Such a transport system has been described for similar secretory vesicles (Toomre et al., 1999). Direct microtubule-dependent transport of connexons to GJ-assembly sites has recently been reported as well (Shaw et al., 2007).
Literature References
PubMed ID
Title
Journal
Year
12149451
Dynamic trafficking and delivery of connexons to the plasma membrane and accretion to gap junctions in living cells
Braconnot, S
,
Lauf, U
,
Chen, SC
,
Giepmans, BN
,
Lopez, P
,
Falk, MM
Proc Natl Acad Sci U S A
2002
Participants
Input
Connexin 43 connexon in Golgi transport vesicle [Golgi-associated vesicle membrane]
(Homo sapiens)
Microtubule [cytosol]
(Homo sapiens)
Output
connexons in Golgi transport vesicle docked to microtubules [Golgi-associated vesicle membrane]
(Homo sapiens)
Participates
as an event of
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane (Homo sapiens)
Orthologous Events
Association of Golgi transport vesicles with microtubules (Bos taurus)
Association of Golgi transport vesicles with microtubules (Canis familiaris)
Association of Golgi transport vesicles with microtubules (Mus musculus)
Association of Golgi transport vesicles with microtubules (Rattus norvegicus)
Association of Golgi transport vesicles with microtubules (Sus scrofa)
Association of Golgi transport vesicles with microtubules (Xenopus tropicalis)
Authored
Gilleron, J (2007-01-03)
Segretain, D (2007-01-03)
Falk, MM (2007-01-03)
Created
Matthews, L (2007-01-09)
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