Internalization of gap junction plaques

Stable Identifier
R-HSA-190519
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane
ReviewStatus
5/5
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Internalization of gap junction plaques
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GJ plaques, clusters of GJ channels, can be internalized to form large, double-membrane vesicles (aka AGJs). Internalized AGJ vesicles subdivide into smaller vesicles that are subsequently degraded by endo/lysosomal pathways (Piehl et al., 2007).

Literature References
PubMed ID Title Journal Year
17108328 Internalization of Large Double-Membrane Intercellular Vesicles by a Clathrin-dependent Endocytic Process

Gumpert, A, Segretain, D, Falk, MM, Piehl, M, Denizot, JP, Lehmann, C

Mol Biol Cell 2007
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Orthologous Events
Internalization of gap junction plaques (Bos taurus)
Internalization of gap junction plaques (Caenorhabditis elegans)
Internalization of gap junction plaques (Canis familiaris)
Internalization of gap junction plaques (Danio rerio)
Internalization of gap junction plaques (Drosophila melanogaster)
Internalization of gap junction plaques (Gallus gallus)
Internalization of gap junction plaques (Mus musculus)
Internalization of gap junction plaques (Rattus norvegicus)
Internalization of gap junction plaques (Sus scrofa)
Internalization of gap junction plaques (Xenopus tropicalis)
Authored
Gilleron, J  (2007-01-03)
Segretain, D  (2007-01-03)
Falk, MM  (2007-01-03)
Reviewed
Falk, MM  (2007-02-02)
Created
Matthews, L  (2007-01-09)
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