Internalization of gap junction plaques

Stable Identifier
R-HSA-190519
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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GJ plaques, clusters of GJ channels, can be internalized to form large, double-membrane vesicles (aka AGJs). Internalized AGJ vesicles subdivide into smaller vesicles that are subsequently degraded by endo/lysosomal pathways (Piehl et al., 2007).

Literature References
PubMed ID Title Journal Year
17108328 Internalization of Large Double-Membrane Intercellular Vesicles by a Clathrin-dependent Endocytic Process

Piehl, M, Lehmann, C, Gumpert, A, Denizot, JP, Segretain, D, Falk, MM

Mol Biol Cell 2007
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