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GRB2 and GAB1 bound to activated FGFR and FRS2-alpha [plasma membrane]
Stable Identifier
R-HSA-190399
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by Insulin receptor (Homo sapiens)
Insulin receptor signalling cascade (Homo sapiens)
IRS-mediated signalling (Homo sapiens)
PI3K Cascade (Homo sapiens)
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Homo sapiens)
PI3K-containing complexes [cytosol] (Homo sapiens)
Activated FGFR bound to PI3K [cytosol] (Homo sapiens)
GRB2 and GAB1 bound to activated FGFR and FRS2-alpha [plasma membrane] (Homo sapiens)
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Homo sapiens)
IGF1R signaling cascade (Homo sapiens)
IRS-related events triggered by IGF1R (Homo sapiens)
IRS-mediated signalling (Homo sapiens)
PI3K Cascade (Homo sapiens)
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Homo sapiens)
PI3K-containing complexes [cytosol] (Homo sapiens)
Activated FGFR bound to PI3K [cytosol] (Homo sapiens)
GRB2 and GAB1 bound to activated FGFR and FRS2-alpha [plasma membrane] (Homo sapiens)
Participants
components
Activated FGFR:p-FRS2:p-PTPN11 [plasma membrane]
(Homo sapiens)
GAB1 [cytosol]
(Homo sapiens)
GRB2-1 [cytosol]
(Homo sapiens)
Participates
as a component of
Activated FGFR bound to PI3K [cytosol] (Homo sapiens)
Inferred To
GRB2 and GAB1 bound to activated FGFR and FRS2-alpha [plasma membrane]
(Bos taurus)
GRB2 and GAB1 bound to activated FGFR and FRS2-alpha [plasma membrane]
(Canis familiaris)
GRB2 and GAB1 bound to activated FGFR and FRS2-alpha [plasma membrane]
(Drosophila melanogaster)
GRB2 and GAB1 bound to activated FGFR and FRS2-alpha [plasma membrane]
(Gallus gallus)
GRB2 and GAB1 bound to activated FGFR and FRS2-alpha [plasma membrane]
(Mus musculus)
GRB2 and GAB1 bound to activated FGFR and FRS2-alpha [plasma membrane]
(Rattus norvegicus)
GRB2 and GAB1 bound to activated FGFR and FRS2-alpha [plasma membrane]
(Sus scrofa)
GRB2 and GAB1 bound to activated FGFR and FRS2-alpha [plasma membrane]
(Xenopus tropicalis)
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