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What is Reactome ?
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Digital Preservation
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TLR10 homodimer [plasma membrane]
Stable Identifier
R-HSA-188112
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of Immune System (Homo sapiens)
Diseases associated with the TLR signaling cascade (Homo sapiens)
IRAK4 deficiency (TLR5) (Homo sapiens)
IRAK4 deficiency blocks formation of the MyD88-IRAK4 Myddosome in the TLR5 pathway (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR10 homodimer bound to ligand [plasma membrane] (Homo sapiens)
TLR10 homodimer [plasma membrane] (Homo sapiens)
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Toll-like Receptor Cascades (Homo sapiens)
Toll Like Receptor 10 (TLR10) Cascade (Homo sapiens)
Ligand binds to TLR10 (Homo sapiens)
TLR10 homodimer bound to ligand [plasma membrane] (Homo sapiens)
TLR10 homodimer [plasma membrane] (Homo sapiens)
MyD88 cascade initiated on plasma membrane (Homo sapiens)
Dissociation of hp-IRAK1:TRAF6 or IRAK2:TRAF6-oligomer from the activated TLR5 or 10:oligo-Myd88:p-IRAK4 complex (Homo sapiens)
TRAF6:hp-IRAK1/or p-IRAK2:p-IRAK4:oligo-MyD88 :activated TLR5 or 10 [plasma membrane] (Homo sapiens)
hp-IRAK1 or p-IRAK2 : pIRAK4:MyD88:activated TLR5/10 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR10 homodimer bound to ligand [plasma membrane] (Homo sapiens)
TLR10 homodimer [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR10 homodimer bound to ligand [plasma membrane] (Homo sapiens)
TLR10 homodimer [plasma membrane] (Homo sapiens)
First phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR (Homo sapiens)
IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR5/10 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR10 homodimer bound to ligand [plasma membrane] (Homo sapiens)
TLR10 homodimer [plasma membrane] (Homo sapiens)
p-IRAK1:p-IRAK4:oligo-MyD88l:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR10 homodimer bound to ligand [plasma membrane] (Homo sapiens)
TLR10 homodimer [plasma membrane] (Homo sapiens)
IRAK1/or IRAK2 binds to the activated IRAK4 :oligo MyD88:activated TLR5 or 10 complex (Homo sapiens)
IRAK1 or IRAK2 :p-IRAK4:MyD88 oligomer:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR10 homodimer bound to ligand [plasma membrane] (Homo sapiens)
TLR10 homodimer [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR10 homodimer bound to ligand [plasma membrane] (Homo sapiens)
TLR10 homodimer [plasma membrane] (Homo sapiens)
IRAK4 autophosphorylation within the complex activated TLR:MyD88 (Homo sapiens)
IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR10 homodimer bound to ligand [plasma membrane] (Homo sapiens)
TLR10 homodimer [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR10 homodimer bound to ligand [plasma membrane] (Homo sapiens)
TLR10 homodimer [plasma membrane] (Homo sapiens)
IRAK4 binds to MyD88 bound to the activated TLR5 or 10 receptor (Homo sapiens)
IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR10 homodimer bound to ligand [plasma membrane] (Homo sapiens)
TLR10 homodimer [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR10 homodimer bound to ligand [plasma membrane] (Homo sapiens)
TLR10 homodimer [plasma membrane] (Homo sapiens)
Multiple IRAK1 autophosphorylation within the complex p-IRAK4:oligo MyD88:activated TLR (Homo sapiens)
hp-IRAK1:activated IRAK4:MyD88oligomer:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR10 homodimer bound to ligand [plasma membrane] (Homo sapiens)
TLR10 homodimer [plasma membrane] (Homo sapiens)
pp-IRAK1:p-IRAK4:oligo-MyD88 :activated TLR5 or 10 complex [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR10 homodimer bound to ligand [plasma membrane] (Homo sapiens)
TLR10 homodimer [plasma membrane] (Homo sapiens)
MyD88 forms a complex with the activated TLR receptor (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR10 homodimer bound to ligand [plasma membrane] (Homo sapiens)
TLR10 homodimer [plasma membrane] (Homo sapiens)
MyD88 complexed with the activated TLR5 or 10 receptor [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR10 homodimer bound to ligand [plasma membrane] (Homo sapiens)
TLR10 homodimer [plasma membrane] (Homo sapiens)
MyD88 oligomerization within the complex of activated TLR:MyD88 (Homo sapiens)
MyD88 complexed with the activated TLR5 or 10 receptor [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR10 homodimer bound to ligand [plasma membrane] (Homo sapiens)
TLR10 homodimer [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR10 homodimer bound to ligand [plasma membrane] (Homo sapiens)
TLR10 homodimer [plasma membrane] (Homo sapiens)
Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomerl:activated TLR5 or 10 complex (Homo sapiens)
IRAK2:p-S,2T-IRAK4:oligo-MyD88:activated TLR5/10 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR10 homodimer bound to ligand [plasma membrane] (Homo sapiens)
TLR10 homodimer [plasma membrane] (Homo sapiens)
p-IRAK2:p-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR10 homodimer bound to ligand [plasma membrane] (Homo sapiens)
TLR10 homodimer [plasma membrane] (Homo sapiens)
Second phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR complex (Homo sapiens)
p-IRAK1:p-IRAK4:oligo-MyD88l:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR10 homodimer bound to ligand [plasma membrane] (Homo sapiens)
TLR10 homodimer [plasma membrane] (Homo sapiens)
pp-IRAK1:p-IRAK4:oligo-MyD88 :activated TLR5 or 10 complex [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR10 homodimer bound to ligand [plasma membrane] (Homo sapiens)
TLR10 homodimer [plasma membrane] (Homo sapiens)
TRAF6 binds to hp- IRAK1 or p-IRAK2 (Homo sapiens)
TRAF6:hp-IRAK1/or p-IRAK2:p-IRAK4:oligo-MyD88 :activated TLR5 or 10 [plasma membrane] (Homo sapiens)
hp-IRAK1 or p-IRAK2 : pIRAK4:MyD88:activated TLR5/10 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR10 homodimer bound to ligand [plasma membrane] (Homo sapiens)
TLR10 homodimer [plasma membrane] (Homo sapiens)
hp-IRAK1 or p-IRAK2 : pIRAK4:MyD88:activated TLR5/10 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR10 homodimer bound to ligand [plasma membrane] (Homo sapiens)
TLR10 homodimer [plasma membrane] (Homo sapiens)
Toll Like Receptor 5 (TLR5) Cascade (Homo sapiens)
MyD88 cascade initiated on plasma membrane (Homo sapiens)
Dissociation of hp-IRAK1:TRAF6 or IRAK2:TRAF6-oligomer from the activated TLR5 or 10:oligo-Myd88:p-IRAK4 complex (Homo sapiens)
TRAF6:hp-IRAK1/or p-IRAK2:p-IRAK4:oligo-MyD88 :activated TLR5 or 10 [plasma membrane] (Homo sapiens)
hp-IRAK1 or p-IRAK2 : pIRAK4:MyD88:activated TLR5/10 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR10 homodimer bound to ligand [plasma membrane] (Homo sapiens)
TLR10 homodimer [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR10 homodimer bound to ligand [plasma membrane] (Homo sapiens)
TLR10 homodimer [plasma membrane] (Homo sapiens)
First phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR (Homo sapiens)
IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR5/10 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR10 homodimer bound to ligand [plasma membrane] (Homo sapiens)
TLR10 homodimer [plasma membrane] (Homo sapiens)
p-IRAK1:p-IRAK4:oligo-MyD88l:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR10 homodimer bound to ligand [plasma membrane] (Homo sapiens)
TLR10 homodimer [plasma membrane] (Homo sapiens)
IRAK1/or IRAK2 binds to the activated IRAK4 :oligo MyD88:activated TLR5 or 10 complex (Homo sapiens)
IRAK1 or IRAK2 :p-IRAK4:MyD88 oligomer:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR10 homodimer bound to ligand [plasma membrane] (Homo sapiens)
TLR10 homodimer [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR10 homodimer bound to ligand [plasma membrane] (Homo sapiens)
TLR10 homodimer [plasma membrane] (Homo sapiens)
IRAK4 autophosphorylation within the complex activated TLR:MyD88 (Homo sapiens)
IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR10 homodimer bound to ligand [plasma membrane] (Homo sapiens)
TLR10 homodimer [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR10 homodimer bound to ligand [plasma membrane] (Homo sapiens)
TLR10 homodimer [plasma membrane] (Homo sapiens)
IRAK4 binds to MyD88 bound to the activated TLR5 or 10 receptor (Homo sapiens)
IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR10 homodimer bound to ligand [plasma membrane] (Homo sapiens)
TLR10 homodimer [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR10 homodimer bound to ligand [plasma membrane] (Homo sapiens)
TLR10 homodimer [plasma membrane] (Homo sapiens)
Multiple IRAK1 autophosphorylation within the complex p-IRAK4:oligo MyD88:activated TLR (Homo sapiens)
hp-IRAK1:activated IRAK4:MyD88oligomer:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR10 homodimer bound to ligand [plasma membrane] (Homo sapiens)
TLR10 homodimer [plasma membrane] (Homo sapiens)
pp-IRAK1:p-IRAK4:oligo-MyD88 :activated TLR5 or 10 complex [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR10 homodimer bound to ligand [plasma membrane] (Homo sapiens)
TLR10 homodimer [plasma membrane] (Homo sapiens)
MyD88 forms a complex with the activated TLR receptor (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR10 homodimer bound to ligand [plasma membrane] (Homo sapiens)
TLR10 homodimer [plasma membrane] (Homo sapiens)
MyD88 complexed with the activated TLR5 or 10 receptor [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR10 homodimer bound to ligand [plasma membrane] (Homo sapiens)
TLR10 homodimer [plasma membrane] (Homo sapiens)
MyD88 oligomerization within the complex of activated TLR:MyD88 (Homo sapiens)
MyD88 complexed with the activated TLR5 or 10 receptor [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR10 homodimer bound to ligand [plasma membrane] (Homo sapiens)
TLR10 homodimer [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR10 homodimer bound to ligand [plasma membrane] (Homo sapiens)
TLR10 homodimer [plasma membrane] (Homo sapiens)
Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomerl:activated TLR5 or 10 complex (Homo sapiens)
IRAK2:p-S,2T-IRAK4:oligo-MyD88:activated TLR5/10 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR10 homodimer bound to ligand [plasma membrane] (Homo sapiens)
TLR10 homodimer [plasma membrane] (Homo sapiens)
p-IRAK2:p-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR10 homodimer bound to ligand [plasma membrane] (Homo sapiens)
TLR10 homodimer [plasma membrane] (Homo sapiens)
Second phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR complex (Homo sapiens)
p-IRAK1:p-IRAK4:oligo-MyD88l:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR10 homodimer bound to ligand [plasma membrane] (Homo sapiens)
TLR10 homodimer [plasma membrane] (Homo sapiens)
pp-IRAK1:p-IRAK4:oligo-MyD88 :activated TLR5 or 10 complex [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR10 homodimer bound to ligand [plasma membrane] (Homo sapiens)
TLR10 homodimer [plasma membrane] (Homo sapiens)
TRAF6 binds to hp- IRAK1 or p-IRAK2 (Homo sapiens)
TRAF6:hp-IRAK1/or p-IRAK2:p-IRAK4:oligo-MyD88 :activated TLR5 or 10 [plasma membrane] (Homo sapiens)
hp-IRAK1 or p-IRAK2 : pIRAK4:MyD88:activated TLR5/10 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR10 homodimer bound to ligand [plasma membrane] (Homo sapiens)
TLR10 homodimer [plasma membrane] (Homo sapiens)
hp-IRAK1 or p-IRAK2 : pIRAK4:MyD88:activated TLR5/10 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR10 homodimer bound to ligand [plasma membrane] (Homo sapiens)
TLR10 homodimer [plasma membrane] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
18332149
The crystal structure of the human toll-like receptor 10 cytoplasmic domain reveals a putative signaling dimer
Hammarström, M
,
Johansson, I
,
Nordlund, P
,
Stenmark, P
,
Flodin, S
,
Nyman, T
J Biol Chem
2008
Participants
components
x 2
TLR10 [plasma membrane]
(Homo sapiens)
Participates
as a component of
TLR10 homodimer bound to ligand [plasma membrane] (Homo sapiens)
Inferred To
TLR10 homodimer [plasma membrane]
(Bos taurus)
TLR10 homodimer [plasma membrane]
(Danio rerio)
TLR10 homodimer [plasma membrane]
(Drosophila melanogaster)
TLR10 homodimer [plasma membrane]
(Gallus gallus)
TLR10 homodimer [plasma membrane]
(Rattus norvegicus)
TLR10 homodimer [plasma membrane]
(Sus scrofa)
TLR10 homodimer [plasma membrane]
(Xenopus tropicalis)
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