Degradation of ubiquitinated CD4

Stable Identifier
R-HSA-180573
Type
Reaction [omitted]
Species
Homo sapiens
Related Species
Human immunodeficiency virus 1
Compartment
ReviewStatus
5/5
Locations in the PathwayBrowser
General
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Ubiquitinated CD4 is then subject to proteasome-mediated degradation.
Literature References
PubMed ID Title Journal Year
9660940 A novel human WD protein, h-beta TrCp, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through an F-box motif

Margottin, F, Richard, V, Benarous, R, Durand, H, Selig, L, Strebel, K, Bour, SP, Thomas, D, Benichou, S

Mol Cell 1998
Participants
Participates
Catalyst Activity

endopeptidase activity of 26S proteasome [cytosol]

Disease
Name Identifier Synonyms
Human immunodeficiency virus infectious disease DOID:526 HIV infection
Authored
Reviewed
Created
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