RPIA isomerizes ribose 5-phosphate to D-ribulose 5-phosphate

Stable Identifier
R-HSA-177784
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
Synonyms
ribose 5-phosphate <=> D-ribulose 5-phosphate
ReviewStatus
5/5
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RPIA isomerizes ribose 5-phosphate to D-ribulose 5-phosphate
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The reversible interconversion of ribose 5-phosphate and ribulose 5-phosphate is catalyzed by cytosolic ribose 5-phosphate isomerase (Huck et al. 2004).
Literature References
PubMed ID Title Journal Year
14988808 Ribose-5-phosphate isomerase deficiency: new inborn error in the pentose phosphate pathway associated with a slowly progressive leukoencephalopathy

Huck, JHJ, Verhoeven, NM, Struys, EA, Salomons, GS, Jakobs, C, van der Knaap, MS

Am J Hum Genet 2004
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Event Information
Reverse Reaction
RPIA isomerizes D-ribulose 5-phosphate to ribose 5-phosphate (Homo sapiens)
Catalyst Activity

ribose-5-phosphate isomerase activity of RPIA [cytosol]

Physical Entity
RPIA [cytosol] (Homo sapiens)
Activity
ribose-5-phosphate isomerase activity (GO:0004751)
Orthologous Events
RPIA isomerizes ribose 5-phosphate to D-ribulose 5-phosphate (Bos taurus)
RPIA isomerizes ribose 5-phosphate to D-ribulose 5-phosphate (Caenorhabditis elegans)
RPIA isomerizes ribose 5-phosphate to D-ribulose 5-phosphate (Canis familiaris)
RPIA isomerizes ribose 5-phosphate to D-ribulose 5-phosphate (Danio rerio)
RPIA isomerizes ribose 5-phosphate to D-ribulose 5-phosphate (Dictyostelium discoideum)
RPIA isomerizes ribose 5-phosphate to D-ribulose 5-phosphate (Drosophila melanogaster)
RPIA isomerizes ribose 5-phosphate to D-ribulose 5-phosphate (Gallus gallus)
RPIA isomerizes ribose 5-phosphate to D-ribulose 5-phosphate (Mus musculus)
RPIA isomerizes ribose 5-phosphate to D-ribulose 5-phosphate (Rattus norvegicus)
RPIA isomerizes ribose 5-phosphate to D-ribulose 5-phosphate (Saccharomyces cerevisiae)
RPIA isomerizes ribose 5-phosphate to D-ribulose 5-phosphate (Schizosaccharomyces pombe)
RPIA isomerizes ribose 5-phosphate to D-ribulose 5-phosphate (Sus scrofa)
RPIA isomerizes ribose 5-phosphate to D-ribulose 5-phosphate (Xenopus tropicalis)
Cross References
RHEA
Created
D'Eustachio, P  (2006-04-05)
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