NAT2 acetylation

Stable Identifier
R-HSA-174967
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Typical NAT 2 substrates were chosen as examples. They are paraxanthine, isoniazid and N-hydroxy 4-aminobiphenyl.

Literature References
PubMed ID Title Journal Year
8353847 Metabolic activation and deactivation of arylamine carcinogens by recombinant human NAT1 and polymorphic NAT2 acetyltransferases

Hein, DW, Doll, MA, Rustan, TD, Gray, K, Feng, Y, Ferguson, RJ, Grant, DM

Carcinogenesis 1993
8068562 N-acetyltransferases, O-acetyltransferases, and N,O-acetyltransferases: enzymology and bioactivation

Hanna, PE

Adv. Pharmacol. 1994
23517104 Arylamine N-acetyltransferases: a structural perspective

Zhou, X, Ma, Z, Dong, D, Wu, B

Br. J. Pharmacol. 2013
Participants
Participates
Catalyst Activity

arylamine N-acetyltransferase activity of AcC-NAT2 [cytosol]

Orthologous Events
Reviewed
Created
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