Reactome | ANAPC11 [nucleoplasm]

ANAPC11 [nucleoplasm]

Stable Identifier

R-HSA-174163

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Apc11

Locations in the PathwayBrowser

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Disease (Homo sapiens)

- Diseases of mitotic cell cycle (Homo sapiens)
  - Aberrant regulation of mitotic cell cycle due to RB1 defects (Homo sapiens)
    - Aberrant regulation of mitotic exit in cancer due to RB1 defects (Homo sapiens)
      - Defective RB1 does not form a complex with SKP2 and FZR1 (Homo sapiens)
        
        Cdh1:phospho-APC/C complex [nucleoplasm] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Homo sapiens)
        
        ANAPC11 [nucleoplasm] (Homo sapiens)

Gene expression (Transcription) (Homo sapiens)

- RNA Polymerase II Transcription (Homo sapiens)
  - Generic Transcription Pathway (Homo sapiens)
    - Transcriptional Regulation by VENTX (Homo sapiens)
      - Regulation of IL6 transcription (Homo sapiens)
        
        Cdh1:phospho-APC/C complex [nucleoplasm] (Homo sapiens)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Homo sapiens)
        
        ANAPC11 [nucleoplasm] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q9NYG5 ANAPC11

Gene Names

ANAPC11, HSPC214

Chain

chain:1-84

Reference Genes

BioGPS Gene:51529 ANAPC11

COSMIC - genes:ANAPC11 ANAPC11

CTD Gene:51529 ANAPC11

dbSNP Gene:51529 ANAPC11

ENSEMBL:ENSG00000141552 ANAPC11

HGNC:14452 ANAPC11

KEGG:hsa:51529 ANAPC11

Monarch:51529 ANAPC11

NCBI Gene:51529 ANAPC11

OMIM:614534 ANAPC11

UCSC:Q9NYG5 ANAPC11

Reference Transcript

Participates

as a component of

Other forms of this molecule

ANAPC11 [cytosol]

Inferred To

apc11 [nucleoplasm] (Schizosaccharomyces pombe)

lmgA [nucleoplasm] (Drosophila melanogaster)

anapc11 [nucleoplasm] (Danio rerio)

anapc11 [nucleoplasm] (Dictyostelium discoideum)

anapc11 [nucleoplasm] (Xenopus tropicalis)

Homologues of ANAPC11 [nucleoplasm] (Bos taurus)

ANAPC11 [nucleoplasm] (Bos taurus)

ANAPC11 [nucleoplasm] (Canis familiaris)

ANAPC11 [nucleoplasm] (Mus musculus)

ANAPC11 [nucleoplasm] (Sus scrofa)

Ghost homologue of ANAPC11 [nucleoplasm] (Gallus gallus)

Ghost homologue of ANAPC11 [nucleoplasm] (Rattus norvegicus)

Cross References

RefSeq

NP_001002245.1, NP_057560.8, NP_001276349.1, NP_001276343.1, NP_001276344.1, NP_001002246.1, NP_001002247.1, NP_001276345.1, NP_001276346.1, NP_001002248.1, NP_001002249.1, NP_001002244.1

OpenTargets

ENSG00000141552

ENSEMBL

ENSP00000463567, ENSP00000459200, ENSP00000339695, ENST00000578550, ENSP00000458515, ENSP00000463640, ENSG00000141552, ENST00000571874, ENST00000571570, ENST00000572851, ENST00000583839, ENSP00000349957, ENST00000577747, ENSP00000461648, ENSP00000460678, ENSP00000464615, ENSP00000458143, ENST00000572639, ENSP00000458265, ENSP00000463598, ENST00000392376, ENSP00000460064, ENST00000575195, ENSP00000376181, ENST00000579978, ENST00000571024, ENST00000574924, ENST00000344877, ENST00000357385

HPA

ENSG00000141552-ANAPC11

GeneCards

ANAPC11

PRO

Q9NYG5

Pharos - Targets

Q9NYG5

PDB

2MT5, 4R2Y, 4UI9, 5A31, 5KHR, 5LCW, 5KHU, 8TAU, 6TNT, 5L9U, 6Q6H, 9GAW, 5L9T, 6TM5, 6Q6G, 9N9R, 9N9S, 8TAR, 6TLJ, 5G04, 5G05, 5JG6, 8PKP

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