SRC-1 autophosphorylates

Stable Identifier
R-HSA-170991
Type
Reaction [transition]
Species
Homo sapiens
Compartment
plasma membrane, cytosol
ReviewStatus
5/5
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SRC-1 autophosphorylates
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The active form of RAL, RAL-GTP, induces a conformational change in SRC-1, which autophosphorylates at tyrosine 419, thereby activating itself.
Participants
Input
Output
Participates
as an event of
Catalyst Activity

protein tyrosine kinase activity of SRC-1 [plasma membrane]

Physical Entity
SRC-1 [plasma membrane] (Homo sapiens)
Activity
protein tyrosine kinase activity (GO:0004713)
This event is regulated
Positively by
Regulator
RAL-GTP [cytosol] (Homo sapiens)
Inferred From
Activation of Src by Ral (Rattus norvegicus)
Authored
Nasi, S  (2006-10-10)
Annibali, D  (2006-10-10)
Reviewed
Greene, LA  (2007-11-08)
Created
Jassal, B  (2006-01-25)
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