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Translocation of Cyclin A:phospho-Cdc2 (Thr 14) to the nucleus
Stable Identifier
R-HSA-170088
Type
Reaction [transition]
Species
Homo sapiens
Compartment
nuclear envelope
ReviewStatus
5/5
Locations in the PathwayBrowser
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Cell Cycle (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
Mitotic G2-G2/M phases (Homo sapiens)
G2/M Transition (Homo sapiens)
Cyclin A/B1/B2 associated events during G2/M transition (Homo sapiens)
Translocation of Cyclin A:phospho-Cdc2 (Thr 14) to the nucleus (Homo sapiens)
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Cyclin A:Cdc2 complexes translocate to the nucleus in G1 and may associate with condensing chromosomes in prophase (Pines and Hunter 1991).
Literature References
PubMed ID
Title
Journal
Year
1717476
Human cyclins A and B1 are differentially located in the cell and undergo cell cycle-dependent nuclear transport
Pines, J
,
Hunter, T
J Cell Biol
1991
Participants
Input
CCNA:p-T14-CDK1 [cytosol]
(Homo sapiens)
Output
CCNA:p-T14-CDK1 [nucleoplasm]
(Homo sapiens)
Participates
as an event of
Cyclin A/B1/B2 associated events during G2/M transition (Homo sapiens)
Orthologous Events
Translocation of Cyclin A:phospho-Cdc2 (Thr 14) to the nucleus (Bos taurus)
Translocation of Cyclin A:phospho-Cdc2 (Thr 14) to the nucleus (Caenorhabditis elegans)
Translocation of Cyclin A:phospho-Cdc2 (Thr 14) to the nucleus (Canis familiaris)
Translocation of Cyclin A:phospho-Cdc2 (Thr 14) to the nucleus (Danio rerio)
Translocation of Cyclin A:phospho-Cdc2 (Thr 14) to the nucleus (Drosophila melanogaster)
Translocation of Cyclin A:phospho-Cdc2 (Thr 14) to the nucleus (Gallus gallus)
Translocation of Cyclin A:phospho-Cdc2 (Thr 14) to the nucleus (Mus musculus)
Translocation of Cyclin A:phospho-Cdc2 (Thr 14) to the nucleus (Rattus norvegicus)
Translocation of Cyclin A:phospho-Cdc2 (Thr 14) to the nucleus (Sus scrofa)
Translocation of Cyclin A:phospho-Cdc2 (Thr 14) to the nucleus (Xenopus tropicalis)
Created
Matthews, L (2005-12-23)
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